SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qfk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
4 / 8 PHE H 443
LEU H 500
ALA H 296
VAL H 429
None
0.68A 1epbB-4qfkH:
undetectable
1epbB-4qfkH:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_A_T44A128_1
(TRANSTHYRETIN)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
5 / 10 LEU H 448
ALA H 452
LEU H 447
GLU H 300
ALA H 460
None
1.24A 1ie4A-4qfkH:
undetectable
1ie4C-4qfkH:
undetectable
1ie4A-4qfkH:
14.25
1ie4C-4qfkH:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
5 / 11 SER H 428
TRP H 377
TRP H 295
ILE H 503
ALA H 378
None
1.40A 1jb0B-4qfkH:
undetectable
1jb0B-4qfkH:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
4 / 7 PHE H 120
PRO H 131
ALA H 191
PHE H 203
None
1.21A 1lqtA-4qfkH:
undetectable
1lqtA-4qfkH:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
4 / 7 PHE H 120
PRO H 131
ALA H 191
PHE H 203
None
1.21A 1lquA-4qfkH:
undetectable
1lquA-4qfkH:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QW6_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
3 / 3 ARG H 301
VAL H 429
TRP H 377
None
1.15A 1qw6A-4qfkH:
undetectable
1qw6A-4qfkH:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
3 / 3 ARG H 301
VAL H 429
TRP H 377
None
1.22A 1qwcA-4qfkH:
undetectable
1qwcA-4qfkH:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
3 / 3 ARG H 301
VAL H 429
TRP H 377
None
1.20A 1vagA-4qfkH:
undetectable
1vagA-4qfkH:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
3 / 3 ARG H 301
VAL H 429
TRP H 377
None
1.21A 1zviA-4qfkH:
undetectable
1zviA-4qfkH:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
4 / 8 VAL H  91
THR H  92
PHE H  93
THR H  94
None
1.10A 2kotB-4qfkH:
undetectable
2kotB-4qfkH:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
4 / 6 TYR H 206
THR H 104
ALA H 105
PRO H 207
None
1.23A 2ql8A-4qfkH:
undetectable
2ql8B-4qfkH:
undetectable
2ql8A-4qfkH:
14.97
2ql8B-4qfkH:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X08_A_ASCA1253_0
(CYTOCHROME C
PEROXIDASE,
MITOCHONDRIAL)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
5 / 9 ALA H 504
ILE H 319
TYR H 327
VAL H 326
ASN H 386
None
1.42A 2x08A-4qfkH:
undetectable
2x08A-4qfkH:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
4 / 7 PRO H 339
SER H 336
PHE H 444
ILE H 337
None
0.87A 2y7kA-4qfkH:
4.7
2y7kA-4qfkH:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
5 / 12 ILE H  65
ILE H 152
PHE H  93
VAL H 118
PHE H 122
None
0.90A 2ygoA-4qfkH:
undetectable
2ygoA-4qfkH:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
4 / 6 TYR H 132
MET H 192
ASN H 197
LEU H 194
None
1.48A 3lslG-4qfkH:
2.3
3lslG-4qfkH:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_B_CL6B506_1
(CHOLESTEROL
24-HYDROXYLASE)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
5 / 12 LEU H 276
THR H 251
ILE H 254
ALA H 255
THR H 259
None
0.93A 3mdvB-4qfkH:
undetectable
3mdvB-4qfkH:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
5 / 11 SER H 428
TRP H 377
TRP H 295
ILE H 503
ALA H 378
None
1.40A 3pcqB-4qfkH:
undetectable
3pcqB-4qfkH:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
3 / 3 THR H 210
ASP H 117
GLU H 189
None
0.72A 3qowA-4qfkH:
undetectable
3qowA-4qfkH:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
5 / 12 PHE H 297
ILE H 503
ILE H 317
LEU H 400
VAL H 405
None
1.06A 3w68D-4qfkH:
undetectable
3w68D-4qfkH:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
4 / 7 ASN H 386
GLY H 432
ILE H 421
PHE H 417
None
0.89A 4ejjA-4qfkH:
undetectable
4ejjA-4qfkH:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_B_PQNB840_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
5 / 9 SER H 428
TRP H 377
TRP H 295
ILE H 503
ALA H 378
None
1.44A 4fe1B-4qfkH:
undetectable
4fe1B-4qfkH:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
4 / 6 PRO H 459
ILE H 418
TYR H 294
PHE H 417
None
1.18A 4g10A-4qfkH:
undetectable
4g10A-4qfkH:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_0
(S-ADENOSYLMETHIONINE
SYNTHASE)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
4 / 8 ARG H 390
LEU H 430
ASN H 386
ILE H 503
None
0.91A 4k0bA-4qfkH:
undetectable
4k0bA-4qfkH:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
3 / 3 ARG H 310
ASP H 427
ASP H 373
None
0.92A 4kicB-4qfkH:
undetectable
4kicB-4qfkH:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
4 / 8 ARG H 390
LEU H 430
ASN H 386
ILE H 503
None
0.75A 4l7iA-4qfkH:
undetectable
4l7iA-4qfkH:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
4 / 7 LEU H 521
GLU H 285
ILE H 519
VAL H 516
None
1.05A 4tvtA-4qfkH:
undetectable
4tvtA-4qfkH:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
4 / 7 PHE H 467
SER H 336
ILE H 292
LEU H 500
None
0.71A 4uymA-4qfkH:
undetectable
4uymA-4qfkH:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
5 / 10 SER H 428
TRP H 377
TRP H 295
ILE H 503
ALA H 378
None
1.35A 4xk8B-4qfkH:
undetectable
4xk8B-4qfkH:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
4 / 6 TYR H 232
LYS H 234
LEU H  78
GLU H  77
None
1.30A 4z4cA-4qfkH:
undetectable
4z4cA-4qfkH:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA903_0
(PROTEIN ARGONAUTE-2)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
4 / 5 TYR H 232
LYS H 234
LEU H  78
GLU H  77
None
1.40A 4z4dA-4qfkH:
undetectable
4z4dA-4qfkH:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
4 / 5 TYR H 232
LYS H 234
LEU H  78
GLU H  77
None
1.40A 4z4hA-4qfkH:
undetectable
4z4hA-4qfkH:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
3 / 3 THR H 210
ASP H 117
GLU H 189
None
0.80A 5fa8A-4qfkH:
undetectable
5fa8A-4qfkH:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
5 / 12 LEU H 500
ILE H 421
GLY H 422
ARG H 425
LEU H 448
None
1.15A 5h5fA-4qfkH:
undetectable
5h5fA-4qfkH:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_B_PQNB1844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
5 / 10 SER H 428
TRP H 377
TRP H 295
ILE H 503
ALA H 378
None
1.31A 5oy0b-4qfkH:
undetectable
5oy0b-4qfkH:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA901_0
(PROTEIN ARGONAUTE-2)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
4 / 5 TYR H 232
LYS H 234
LEU H  78
GLU H  77
None
1.28A 6cbdA-4qfkH:
undetectable
6cbdA-4qfkH:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
4 / 5 ALA H  35
TYR H 244
GLN H 510
ILE H 527
None
1.30A 6g9bA-4qfkH:
undetectable
6g9bB-4qfkH:
undetectable
6g9bA-4qfkH:
10.81
6g9bB-4qfkH:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_B_6J3B201_0
(TRANSTHYRETIN)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
4 / 4 LYS H 457
LEU H 447
ALA H 452
LEU H 448
None
1.30A 6gnrB-4qfkH:
undetectable
6gnrB-4qfkH:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_B_PQNB2002_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)
4qfk ABC TRANSPORTER
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Pseudoalteromona
s
sp.
SM9913)
5 / 9 SER H 428
TRP H 377
TRP H 295
ILE H 503
ALA H 378
None
1.38A 6hqbB-4qfkH:
undetectable
6hqbB-4qfkH:
9.53