SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qfu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		5 / 12 ILE A 130
GLY A 142
ILE A 139
VAL A  91
ASN A 177
 None
 1.25A 1sg9A-4qfuA:
undetectable		 1sg9A-4qfuA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_B_TRPB603_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		5 / 12 GLY A  57
GLY A 323
GLN A  88
THR A  59
ILE A 279
 None
 1.36A 2azxB-4qfuA:
undetectable		 2azxB-4qfuA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DR2_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		5 / 11 GLY A  57
GLY A 323
GLN A  88
THR A  59
ILE A 279
 None
 1.33A 2dr2A-4qfuA:
undetectable		 2dr2A-4qfuA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		5 / 12 GLY A 142
GLN A  88
LEU A  76
MET A 127
MET A  63
 None
 1.10A 2prgA-4qfuA:
undetectable		 2prgA-4qfuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		5 / 12 GLY A 142
GLN A  88
TYR A  75
LEU A  76
MET A  63
 None
 1.16A 2prgA-4qfuA:
undetectable		 2prgA-4qfuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA142_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		4 / 5 GLU A 282
PRO A 283
ILE A 284
GLY A 239
 MRD  A 501 (-2.7A)
None
None
None
 0.78A 2qeuA-4qfuA:
undetectable
2qeuC-4qfuA:
undetectable		 2qeuA-4qfuA:
15.78
2qeuC-4qfuA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		3 / 3 VAL A 313
TRP A 263
TRP A 311
 None
 1.32A 2xdcC-4qfuA:
undetectable
2xdcD-4qfuA:
undetectable		 2xdcC-4qfuA:
5.02
2xdcD-4qfuA:
5.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		5 / 10 GLY A 142
LEU A  76
ILE A 131
MET A 127
MET A  63
 None
 1.20A 3adsA-4qfuA:
undetectable		 3adsA-4qfuA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		4 / 7 GLY A 323
ASP A 287
TYR A 285
ARG A 299
 None
 1.20A 3arrA-4qfuA:
5.4		 3arrA-4qfuA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		4 / 7 GLY A 323
ASP A 287
TYR A 285
ARG A 299
 None
 1.12A 3aruA-4qfuA:
10.7		 3aruA-4qfuA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		3 / 3 SER A 444
ASP A 415
ASP A 467
 None
 0.83A 3iv6A-4qfuA:
undetectable		 3iv6A-4qfuA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_A_EVPA1_1
(DNA TOPOISOMERASE
2-BETA)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		4 / 5 GLY A 434
ASP A 433
ARG A 306
MET A 412
 None
 1.47A 3qx3A-4qfuA:
undetectable		 3qx3A-4qfuA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD506_1
(HEMOLYTIC LECTIN
CEL-III)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		4 / 5 ASP A 280
GLU A 282
GLY A 239
TYR A 308
 None
MRD  A 501 (-2.7A)
None
None
 1.42A 3w9tD-4qfuA:
undetectable		 3w9tD-4qfuA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		3 / 3 VAL A 313
TRP A 263
TRP A 311
 None
 1.35A 3zq8A-4qfuA:
undetectable
3zq8B-4qfuA:
undetectable		 3zq8A-4qfuA:
5.02
3zq8B-4qfuA:
5.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		4 / 8 GLN A  90
GLN A 237
ILE A 288
PHE A 339
 MRD  A 502 (-3.1A)
MRD  A 501 (-3.8A)
None
MRD  A 502 (-4.6A)
 0.94A 4dx7B-4qfuA:
undetectable		 4dx7B-4qfuA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1Q_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		5 / 12 LEU A 366
VAL A 473
TYR A 401
TYR A 472
PRO A 481
 None
 1.30A 4g1qA-4qfuA:
0.1		 4g1qA-4qfuA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ID5_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		5 / 12 LEU A 366
VAL A 473
TYR A 401
TYR A 472
PRO A 481
 None
 1.31A 4id5A-4qfuA:
undetectable		 4id5A-4qfuA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IFY_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		5 / 12 LEU A 366
VAL A 473
TYR A 401
TYR A 472
PRO A 481
 None
 1.32A 4ifyA-4qfuA:
undetectable		 4ifyA-4qfuA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG3_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		5 / 12 LEU A 366
VAL A 473
TYR A 401
TYR A 472
PRO A 481
 None
 1.32A 4ig3A-4qfuA:
undetectable		 4ig3A-4qfuA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		4 / 8 SER A 430
ASP A 433
GLN A 461
THR A 478
 None
 1.01A 4lnwA-4qfuA:
undetectable		 4lnwA-4qfuA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		4 / 5 ARG A 216
GLN A 237
PRO A 215
ILE A 186
 MRD  A 501 ( 4.7A)
MRD  A 501 (-3.8A)
None
CL  A 503 ( 4.7A)
 1.29A 4z4hA-4qfuA:
2.2		 4z4hA-4qfuA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZP0_A_DXCA500_0
(MULTIDRUG
TRANSPORTER MDFA)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		5 / 10 MET A 367
LEU A 363
GLY A 356
GLN A 359
MET A 360
 None
 1.50A 4zp0A-4qfuA:
undetectable		 4zp0A-4qfuA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZP0_A_DXCA500_0
(MULTIDRUG
TRANSPORTER MDFA)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		5 / 10 TYR A 405
MET A 367
GLY A 356
GLN A 359
MET A 360
 None
 1.44A 4zp0A-4qfuA:
undetectable		 4zp0A-4qfuA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		5 / 12 GLU A 175
ILE A 484
TYR A  28
LEU A  36
HIS A 209
 None
 1.01A 5esgA-4qfuA:
undetectable		 5esgA-4qfuA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		6 / 12 TYR A 123
PHE A 112
ILE A 115
PHE A 110
GLY A 109
THR A 149
 None
 1.50A 5eskA-4qfuA:
undetectable		 5eskA-4qfuA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_A_KANA600_1
(BIFUNCTIONAL AAC/APH)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		5 / 12 ASP A 391
SER A 408
ASN A 406
TYR A 455
SER A 453
 None
 1.46A 5iqbA-4qfuA:
2.1		 5iqbA-4qfuA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_D_KAND600_1
(BIFUNCTIONAL AAC/APH)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		5 / 12 ASP A 391
SER A 408
ASN A 406
TYR A 455
SER A 453
 None
 1.46A 5iqbD-4qfuA:
2.0		 5iqbD-4qfuA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_C_RIOC600_0
(BIFUNCTIONAL AAC/APH)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		5 / 12 ASP A 391
SER A 408
ASN A 406
TYR A 455
SER A 453
 None
 1.37A 5iqdC-4qfuA:
undetectable		 5iqdC-4qfuA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_C_NMYC600_1
(BIFUNCTIONAL AAC/APH)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		5 / 12 ASP A 391
SER A 408
ASN A 406
TYR A 455
SER A 453
 None
 1.44A 5iqeC-4qfuA:
undetectable		 5iqeC-4qfuA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_D_NMYD600_1
(BIFUNCTIONAL AAC/APH)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		5 / 12 ASP A 391
SER A 408
ASN A 406
TYR A 455
SER A 453
 None
 1.46A 5iqeD-4qfuA:
1.2		 5iqeD-4qfuA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		4 / 5 ARG A 216
GLN A 237
PRO A 215
ILE A 186
 MRD  A 501 ( 4.7A)
MRD  A 501 (-3.8A)
None
CL  A 503 ( 4.7A)
 1.36A 5ki6A-4qfuA:
2.1		 5ki6A-4qfuA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_A_ADNA401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		4 / 7 GLY A 208
LYS A 173
ALA A 169
ASP A 174
 None
 0.86A 5mvsA-4qfuA:
undetectable		 5mvsA-4qfuA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_B_ADNB401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		4 / 8 GLY A 208
LYS A 173
ALA A 169
ASP A 174
 None
 0.75A 5mvsB-4qfuA:
undetectable		 5mvsB-4qfuA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N9X_A_THRA601_0
(ADENYLATION DOMAIN)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		4 / 7 ASP A 280
PHE A 265
GLY A 217
GLY A 239
 None
 0.84A 5n9xA-4qfuA:
undetectable		 5n9xA-4qfuA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		4 / 7 TYR A  28
GLN A 485
ASP A 482
TYR A 140
 None
 1.46A 5ov9B-4qfuA:
undetectable		 5ov9B-4qfuA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		5 / 12 GLY A 142
GLN A  88
LEU A  76
ILE A 131
MET A 127
 None
 0.94A 5y2tA-4qfuA:
undetectable		 5y2tA-4qfuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		5 / 12 GLY A 142
LEU A  76
ILE A 131
MET A 127
MET A  63
 None
 1.04A 5y2tA-4qfuA:
undetectable		 5y2tA-4qfuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		6 / 12 LEU A 168
GLY A 142
GLN A  88
TYR A  75
LEU A  76
ILE A 131
 None
 1.17A 5y2tA-4qfuA:
undetectable		 5y2tA-4qfuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_D_EVPD101_1
()		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		4 / 5 GLY A 434
ASP A 433
ARG A 306
MET A 412
 None
 1.49A 5zrfB-4qfuA:
undetectable		 5zrfB-4qfuA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_F_EVPF1301_1
()		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		4 / 4 GLY A 434
ASP A 433
ARG A 306
MET A 412
 None
 1.48A 5zrfA-4qfuA:
undetectable		 5zrfA-4qfuA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		4 / 6 ALA A 222
SER A 221
ALA A 268
SER A 269
 None
 0.99A 6bocA-4qfuA:
undetectable
6bocB-4qfuA:
undetectable
6bocC-4qfuA:
undetectable
6bocD-4qfuA:
undetectable		 6bocA-4qfuA:
5.53
6bocB-4qfuA:
5.53
6bocC-4qfuA:
5.53
6bocD-4qfuA:
5.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C5U_A_RIOA600_0
(BIFUNCTIONAL AAC/APH)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		5 / 10 ASP A 391
SER A 408
ASN A 406
TYR A 455
SER A 453
 None
 1.42A 6c5uA-4qfuA:
0.4		 6c5uA-4qfuA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C5U_D_RIOD600_0
(BIFUNCTIONAL AAC/APH)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		5 / 10 ASP A 391
SER A 408
ASN A 406
TYR A 455
SER A 453
 None
 1.42A 6c5uD-4qfuA:
0.7		 6c5uD-4qfuA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		5 / 12 TYR A  75
ILE A 327
HIS A 324
VAL A 305
ALA A  82
 None
 1.08A 6djzA-4qfuA:
2.9		 6djzA-4qfuA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_B_TRPB502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 4qfu GLYCOSIDE HYDROLASE
FAMILY 5
(Bacteroides
vulgatus) 		5 / 10 TYR A 322
ALA A 309
LEU A 363
LEU A  56
TYR A  84
 None
 1.37A 6g2pB-4qfuA:
undetectable		 6g2pB-4qfuA:
20.66