SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qfv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)		 4qfv ANK-N5C-281
(synthetic
construct) 		3 / 3 ASP A  35
ARG A  14
ASP A  68
 None
 0.90A 1vptA-4qfvA:
undetectable		 1vptA-4qfvA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_A_DESA600_1
(ESTROGEN RECEPTOR
ALPHA)		 4qfv ANK-N5C-281
(synthetic
construct) 		5 / 12 LEU A  10
ALA A  12
LEU A  25
LEU A  24
LEU A  57
 None
 1.12A 3erdA-4qfvA:
undetectable		 3erdA-4qfvA:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 4qfv ANK-N5C-281
(synthetic
construct) 		5 / 12 LEU A  10
ALA A  12
LEU A  25
LEU A  24
LEU A  57
 None
 1.12A 3hm1A-4qfvA:
undetectable		 3hm1A-4qfvA:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 4qfv ANK-N5C-281
(synthetic
construct) 		5 / 5 LYS A  88
LEU A  89
GLU A  85
LEU A  51
LYS A  55
 None
 1.44A 4k4yA-4qfvA:
undetectable		 4k4yA-4qfvA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 4qfv ANK-N5C-281
(synthetic
construct) 		4 / 4 LYS A  88
LEU A  89
GLU A  85
LEU A  51
 None
 1.37A 4k4yE-4qfvA:
undetectable		 4k4yE-4qfvA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 4qfv ANK-N5C-281
(synthetic
construct) 		5 / 5 LYS A  88
LEU A  89
GLU A  85
LEU A  51
LYS A  55
 None
 1.46A 4k4yI-4qfvA:
undetectable		 4k4yI-4qfvA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 4qfv ANK-N5C-281
(synthetic
construct) 		4 / 5 LEU A 174
SER A 176
LEU A 185
LEU A 222
 None
 1.24A 4n09B-4qfvA:
undetectable		 4n09B-4qfvA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 4qfv ANK-N5C-281
(synthetic
construct) 		4 / 5 LEU A 174
SER A 176
LEU A 185
LEU A 222
 None
 1.24A 4n09D-4qfvA:
undetectable		 4n09D-4qfvA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)		 4qfv ANK-N5C-281
(synthetic
construct) 		5 / 11 LEU A  10
ALA A  12
LEU A  25
LEU A  24
LEU A  57
 None
 1.16A 4zn7B-4qfvA:
undetectable		 4zn7B-4qfvA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 4qfv ANK-N5C-281
(synthetic
construct) 		4 / 8 ILE A  97
VAL A  87
GLU A 118
LEU A 122
 None
 0.77A 5og9A-4qfvA:
undetectable		 5og9A-4qfvA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 4qfv ANK-N5C-281
(synthetic
construct) 		4 / 8 ILE A 130
VAL A 120
GLU A 151
LEU A 155
 None
 0.75A 5og9A-4qfvA:
undetectable		 5og9A-4qfvA:
20.04