SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qgs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 12 GLY A  93
GLY A  94
CYH A 135
ALA A 173
LEU A 175
 None
 0.99A 1bx4A-4qgsA:
undetectable		 1bx4A-4qgsA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 5 GLY A 270
LEU A 273
THR A 274
VAL A 288
 None
 0.94A 1ekjF-4qgsA:
2.3
1ekjG-4qgsA:
2.0		 1ekjF-4qgsA:
21.83
1ekjG-4qgsA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 SER A 129
ALA A 130
GLY A 124
ALA A 106
ILE A 119
 None
 1.11A 1gtnB-4qgsA:
undetectable
1gtnC-4qgsA:
undetectable		 1gtnB-4qgsA:
11.89
1gtnC-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 SER A 129
ALA A 130
GLY A 124
ALA A 106
ILE A 119
 None
 1.15A 1gtnH-4qgsA:
undetectable
1gtnI-4qgsA:
undetectable		 1gtnH-4qgsA:
11.89
1gtnI-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 8 ALA A 130
GLY A 124
ALA A 106
ILE A 119
 None
 0.56A 1gtnI-4qgsA:
undetectable
1gtnJ-4qgsA:
undetectable		 1gtnI-4qgsA:
11.89
1gtnJ-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 11 GLY A 124
ALA A 106
ILE A 119
SER A 129
ALA A 130
 None
 1.16A 1gtnM-4qgsA:
undetectable
1gtnN-4qgsA:
undetectable		 1gtnM-4qgsA:
11.89
1gtnN-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 GLY A 124
ALA A 106
ILE A 119
SER A 129
ALA A 130
 None
 1.15A 1gtnU-4qgsA:
undetectable
1gtnV-4qgsA:
undetectable		 1gtnU-4qgsA:
11.89
1gtnV-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 11 GLY A  93
ILE A  34
LEU A  90
GLY A  37
THR A 138
 None
 1.11A 1jg3A-4qgsA:
undetectable		 1jg3A-4qgsA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 11 GLY A  93
ILE A  34
LEU A  90
GLY A  37
THR A 138
 None
 1.10A 1jg3B-4qgsA:
undetectable		 1jg3B-4qgsA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 8 GLY A 270
MET A 276
ILE A 287
VAL A 288
 None
 0.81A 1rxcB-4qgsA:
undetectable		 1rxcB-4qgsA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 7 GLY A 270
MET A 276
ILE A 287
VAL A 288
 None
 0.84A 1rxcC-4qgsA:
undetectable		 1rxcC-4qgsA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 7 GLY A 270
MET A 276
ILE A 287
VAL A 288
 None
 0.78A 1rxcD-4qgsA:
undetectable		 1rxcD-4qgsA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 8 GLY A 270
MET A 276
ILE A 287
VAL A 288
 None
 0.80A 1rxcE-4qgsA:
undetectable		 1rxcE-4qgsA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 7 GLY A 270
MET A 276
ILE A 287
VAL A 288
 None
 0.79A 1rxcF-4qgsA:
undetectable		 1rxcF-4qgsA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 8 GLY A 270
MET A 276
ILE A 287
VAL A 288
 None
 0.82A 1rxcI-4qgsA:
undetectable		 1rxcI-4qgsA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 8 GLY A 270
MET A 276
ILE A 287
VAL A 288
 None
 0.82A 1rxcK-4qgsA:
undetectable		 1rxcK-4qgsA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 7 GLY A 270
MET A 276
ILE A 287
VAL A 288
 None
 0.79A 1rxcL-4qgsA:
2.2		 1rxcL-4qgsA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 GLY A 124
ALA A 106
ILE A 119
SER A 129
ALA A 130
 None
 1.13A 1utdT-4qgsA:
undetectable
1utdU-4qgsA:
undetectable		 1utdT-4qgsA:
11.89
1utdU-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 7 PHE A 334
LEU A 221
VAL A 200
THR A 199
 None
 0.93A 2qblA-4qgsA:
undetectable		 2qblA-4qgsA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_D_2FAD500_1
(ADENOSYLHOMOCYSTEINA
SE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 12 HIS A 281
THR A 274
ASP A 194
HIS A 198
GLY A 270
 ZN  A 401 (-3.3A)
None
ZN  A 401 (-2.5A)
ZN  A 401 (-3.2A)
None
 1.27A 2zj0D-4qgsA:
undetectable		 2zj0D-4qgsA:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_2
(PROTEASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 ASP A  99
ILE A  65
LEU A  90
VAL A  81
ILE A 104
 None
 1.08A 3em4V-4qgsA:
undetectable		 3em4V-4qgsA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 9 GLY A 134
GLN A  25
ILE A  34
VAL A  92
VAL A 136
 None
 1.26A 3fi0A-4qgsA:
undetectable		 3fi0A-4qgsA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 9 GLY A 134
GLN A  25
ILE A  34
VAL A  92
VAL A 136
 None
 1.32A 3fi0C-4qgsA:
undetectable		 3fi0C-4qgsA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 9 GLY A 134
GLN A  25
ILE A  34
VAL A  92
VAL A 136
 None
 1.27A 3fi0L-4qgsA:
undetectable		 3fi0L-4qgsA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 9 GLY A 134
GLN A  25
ILE A  34
VAL A  92
VAL A 136
 None
 1.31A 3fi0M-4qgsA:
undetectable		 3fi0M-4qgsA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 6 GLY A 270
MET A 276
ILE A 287
VAL A 288
 None
 0.80A 3kvvA-4qgsA:
undetectable		 3kvvA-4qgsA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 6 GLY A 270
MET A 276
ILE A 287
VAL A 288
 None
 0.80A 3kvvB-4qgsA:
undetectable		 3kvvB-4qgsA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 6 GLY A 270
MET A 276
ILE A 287
VAL A 288
 None
 0.83A 3kvvC-4qgsA:
undetectable		 3kvvC-4qgsA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 6 GLY A 270
MET A 276
ILE A 287
VAL A 288
 None
 0.79A 3kvvD-4qgsA:
undetectable		 3kvvD-4qgsA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 6 GLY A 270
MET A 276
ILE A 287
VAL A 288
 None
 0.81A 3kvvE-4qgsA:
undetectable		 3kvvE-4qgsA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 6 GLY A 270
MET A 276
ILE A 287
VAL A 288
 None
 0.81A 3kvvF-4qgsA:
undetectable		 3kvvF-4qgsA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA207_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 7 GLU A 370
LEU A 292
ASP A 263
ALA A 265
 None
 1.23A 3mbgA-4qgsA:
1.8
3mbgB-4qgsA:
1.7		 3mbgA-4qgsA:
17.62
3mbgB-4qgsA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_A_9PLA501_1
(CYTOCHROME P450 2E1)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 6 PHE A 172
LEU A  54
ALA A  91
THR A  35
 None
 0.99A 3t3zA-4qgsA:
undetectable		 3t3zA-4qgsA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_B_9PLB501_1
(CYTOCHROME P450 2E1)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 6 PHE A 172
LEU A  54
ALA A  91
THR A  35
 None
 0.94A 3t3zB-4qgsA:
undetectable		 3t3zB-4qgsA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_D_9PLD501_1
(CYTOCHROME P450 2E1)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 6 PHE A 172
LEU A  54
ALA A  91
THR A  35
 None
 0.97A 3t3zD-4qgsA:
undetectable		 3t3zD-4qgsA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 8 ASP A 194
GLY A 191
VAL A 197
VAL A 339
 ZN  A 401 (-2.5A)
None
None
None
 0.78A 4c5nC-4qgsA:
5.7		 4c5nC-4qgsA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 8 GLY A 270
MET A 276
ILE A 287
VAL A 288
 None
 0.78A 4e1vA-4qgsA:
undetectable		 4e1vA-4qgsA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 7 GLY A 270
MET A 276
ILE A 287
VAL A 288
 None
 0.83A 4e1vB-4qgsA:
undetectable		 4e1vB-4qgsA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 8 GLY A 270
MET A 276
ILE A 287
VAL A 288
 None
 0.79A 4e1vC-4qgsA:
undetectable		 4e1vC-4qgsA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 8 GLY A 270
MET A 276
ILE A 287
VAL A 288
 None
 0.80A 4e1vD-4qgsA:
undetectable		 4e1vD-4qgsA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 8 GLY A 270
MET A 276
ILE A 287
VAL A 288
 None
 0.81A 4e1vE-4qgsA:
undetectable		 4e1vE-4qgsA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 6 GLY A 270
MET A 276
ILE A 287
VAL A 288
 None
 0.79A 4e1vF-4qgsA:
undetectable		 4e1vF-4qgsA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 8 GLY A 270
MET A 276
ILE A 287
VAL A 288
 None
 0.81A 4e1vG-4qgsA:
undetectable		 4e1vG-4qgsA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 8 GLY A 270
MET A 276
ILE A 287
VAL A 288
 None
 0.79A 4e1vH-4qgsA:
undetectable		 4e1vH-4qgsA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_C_FOLC703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 11 VAL A  92
PHE A  88
LEU A  22
VAL A 136
THR A 101
 None
 1.36A 4eilC-4qgsA:
2.7		 4eilC-4qgsA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 11 ASP A 227
PRO A 185
VAL A 188
ALA A 189
THR A 180
 None
 0.99A 4mmaA-4qgsA:
undetectable		 4mmaA-4qgsA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		3 / 3 TYR A 179
THR A 182
THR A 138
 None
 0.60A 5aoxB-4qgsA:
undetectable		 5aoxB-4qgsA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		3 / 3 TYR A 179
THR A 182
THR A 138
 None
 0.62A 5aoxE-4qgsA:
undetectable		 5aoxE-4qgsA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_F_SAMF301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 12 GLY A  93
GLY A  94
GLY A  95
LEU A  98
LEU A  90
 None
 0.92A 5c0oF-4qgsA:
3.0		 5c0oF-4qgsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 SER A 129
ALA A 130
GLY A 124
ALA A 106
ILE A 119
 None
 1.12A 5eeuF-4qgsA:
undetectable
5eeuG-4qgsA:
undetectable		 5eeuF-4qgsA:
11.89
5eeuG-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 12 SER A 129
ALA A 130
GLY A 124
ALA A 106
ILE A 119
 None
 1.10A 5eeuI-4qgsA:
undetectable
5eeuJ-4qgsA:
undetectable		 5eeuI-4qgsA:
11.89
5eeuJ-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 GLY A 124
ALA A 106
ILE A 119
SER A 129
ALA A 130
 None
 1.15A 5eeuO-4qgsA:
undetectable
5eeuP-4qgsA:
undetectable		 5eeuO-4qgsA:
11.89
5eeuP-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 GLY A 124
ALA A 106
ILE A 119
SER A 129
ALA A 130
 None
 1.14A 5eeuQ-4qgsA:
undetectable
5eeuR-4qgsA:
undetectable		 5eeuQ-4qgsA:
11.89
5eeuR-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 SER A 129
ALA A 130
GLY A 124
ALA A 106
ILE A 119
 None
 1.12A 5eevF-4qgsA:
undetectable
5eevG-4qgsA:
undetectable		 5eevF-4qgsA:
11.89
5eevG-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 12 SER A 129
ALA A 130
GLY A 124
ALA A 106
ILE A 119
 None
 1.10A 5eevI-4qgsA:
undetectable
5eevJ-4qgsA:
undetectable		 5eevI-4qgsA:
11.89
5eevJ-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 GLY A 124
ALA A 106
ILE A 119
SER A 129
ALA A 130
 None
 1.15A 5eevO-4qgsA:
undetectable
5eevP-4qgsA:
undetectable		 5eevO-4qgsA:
11.89
5eevP-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 GLY A 124
ALA A 106
ILE A 119
SER A 129
ALA A 130
 None
 1.14A 5eevQ-4qgsA:
undetectable
5eevR-4qgsA:
undetectable		 5eevQ-4qgsA:
11.89
5eevR-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 SER A 129
ALA A 130
GLY A 124
ALA A 106
ILE A 119
 None
 1.12A 5eewF-4qgsA:
undetectable
5eewG-4qgsA:
undetectable		 5eewF-4qgsA:
11.89
5eewG-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 12 SER A 129
ALA A 130
GLY A 124
ALA A 106
ILE A 119
 None
 1.10A 5eewI-4qgsA:
undetectable
5eewJ-4qgsA:
undetectable		 5eewI-4qgsA:
11.89
5eewJ-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 GLY A 124
ALA A 106
ILE A 119
SER A 129
ALA A 130
 None
 1.15A 5eewO-4qgsA:
undetectable
5eewP-4qgsA:
undetectable		 5eewO-4qgsA:
11.89
5eewP-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 GLY A 124
ALA A 106
ILE A 119
SER A 129
ALA A 130
 None
 1.14A 5eewQ-4qgsA:
undetectable
5eewR-4qgsA:
undetectable		 5eewQ-4qgsA:
11.89
5eewR-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 SER A 129
ALA A 130
GLY A 124
ALA A 106
ILE A 119
 None
 1.12A 5eexF-4qgsA:
undetectable
5eexG-4qgsA:
undetectable		 5eexF-4qgsA:
11.89
5eexG-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 GLY A 124
ALA A 106
ILE A 119
SER A 129
ALA A 130
 None
 1.15A 5eexO-4qgsA:
undetectable
5eexP-4qgsA:
undetectable		 5eexO-4qgsA:
11.89
5eexP-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 SER A 129
ALA A 130
GLY A 124
ALA A 106
ILE A 119
 None
 1.12A 5eeyF-4qgsA:
undetectable
5eeyG-4qgsA:
undetectable		 5eeyF-4qgsA:
11.89
5eeyG-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 GLY A 124
ALA A 106
ILE A 119
SER A 129
ALA A 130
 None
 1.15A 5eeyO-4qgsA:
undetectable
5eeyP-4qgsA:
undetectable		 5eeyO-4qgsA:
11.89
5eeyP-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 SER A 129
ALA A 130
GLY A 124
ALA A 106
ILE A 119
 None
 1.12A 5eezF-4qgsA:
undetectable
5eezG-4qgsA:
undetectable		 5eezF-4qgsA:
11.89
5eezG-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 GLY A 124
ALA A 106
ILE A 119
SER A 129
ALA A 130
 None
 1.15A 5eezO-4qgsA:
undetectable
5eezP-4qgsA:
undetectable		 5eezO-4qgsA:
11.89
5eezP-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 SER A 129
ALA A 130
GLY A 124
ALA A 106
ILE A 119
 None
 1.12A 5ef0F-4qgsA:
undetectable
5ef0G-4qgsA:
undetectable		 5ef0F-4qgsA:
11.89
5ef0G-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 GLY A 124
ALA A 106
ILE A 119
SER A 129
ALA A 130
 None
 1.15A 5ef0O-4qgsA:
undetectable
5ef0P-4qgsA:
undetectable		 5ef0O-4qgsA:
11.89
5ef0P-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 SER A 129
ALA A 130
GLY A 124
ALA A 106
ILE A 119
 None
 1.12A 5ef1F-4qgsA:
undetectable
5ef1G-4qgsA:
undetectable		 5ef1F-4qgsA:
11.89
5ef1G-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 GLY A 124
ALA A 106
ILE A 119
SER A 129
ALA A 130
 None
 1.15A 5ef1O-4qgsA:
undetectable
5ef1P-4qgsA:
undetectable		 5ef1O-4qgsA:
11.89
5ef1P-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 SER A 129
ALA A 130
GLY A 124
ALA A 106
ILE A 119
 None
 1.12A 5ef2F-4qgsA:
undetectable
5ef2G-4qgsA:
undetectable		 5ef2F-4qgsA:
11.89
5ef2G-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 GLY A 124
ALA A 106
ILE A 119
SER A 129
ALA A 130
 None
 1.15A 5ef2O-4qgsA:
undetectable
5ef2P-4qgsA:
undetectable		 5ef2O-4qgsA:
11.89
5ef2P-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 SER A 129
ALA A 130
GLY A 124
ALA A 106
ILE A 119
 None
 1.12A 5ef3F-4qgsA:
undetectable
5ef3G-4qgsA:
undetectable		 5ef3F-4qgsA:
11.89
5ef3G-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 10 GLY A 124
ALA A 106
ILE A 119
SER A 129
ALA A 130
 None
 1.14A 5ef3O-4qgsA:
undetectable
5ef3P-4qgsA:
undetectable		 5ef3O-4qgsA:
11.89
5ef3P-4qgsA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESM_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 7 PHE A 163
ILE A 119
GLY A 100
LEU A  89
 None
 1.01A 5esmA-4qgsA:
undetectable		 5esmA-4qgsA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 8 LEU A  90
LEU A  98
THR A 138
TYR A 179
 None
 1.18A 5hbsA-4qgsA:
undetectable		 5hbsA-4qgsA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 4 LEU A 292
LEU A 368
GLY A 369
GLU A 370
 None
 1.25A 5hhjA-4qgsA:
undetectable		 5hhjA-4qgsA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 12 HIS A 281
THR A 274
ASP A 194
HIS A 198
GLY A 270
 ZN  A 401 (-3.3A)
None
ZN  A 401 (-2.5A)
ZN  A 401 (-3.2A)
None
 1.30A 5hm8A-4qgsA:
undetectable		 5hm8A-4qgsA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 12 HIS A 281
THR A 274
ASP A 194
HIS A 198
GLY A 270
 ZN  A 401 (-3.3A)
None
ZN  A 401 (-2.5A)
ZN  A 401 (-3.2A)
None
 1.30A 5hm8B-4qgsA:
undetectable		 5hm8B-4qgsA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 12 HIS A 281
THR A 274
ASP A 194
HIS A 198
GLY A 270
 ZN  A 401 (-3.3A)
None
ZN  A 401 (-2.5A)
ZN  A 401 (-3.2A)
None
 1.30A 5hm8C-4qgsA:
undetectable		 5hm8C-4qgsA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 12 HIS A 281
THR A 274
ASP A 194
HIS A 198
GLY A 270
 ZN  A 401 (-3.3A)
None
ZN  A 401 (-2.5A)
ZN  A 401 (-3.2A)
None
 1.30A 5hm8D-4qgsA:
undetectable		 5hm8D-4qgsA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 12 HIS A 281
THR A 274
ASP A 194
HIS A 198
GLY A 270
 ZN  A 401 (-3.3A)
None
ZN  A 401 (-2.5A)
ZN  A 401 (-3.2A)
None
 1.30A 5hm8E-4qgsA:
undetectable		 5hm8E-4qgsA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 12 HIS A 281
THR A 274
ASP A 194
HIS A 198
GLY A 270
 ZN  A 401 (-3.3A)
None
ZN  A 401 (-2.5A)
ZN  A 401 (-3.2A)
None
 1.31A 5hm8F-4qgsA:
undetectable		 5hm8F-4qgsA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 12 HIS A 281
THR A 274
ASP A 194
HIS A 198
GLY A 270
 ZN  A 401 (-3.3A)
None
ZN  A 401 (-2.5A)
ZN  A 401 (-3.2A)
None
 1.29A 5hm8G-4qgsA:
undetectable		 5hm8G-4qgsA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		5 / 12 HIS A 281
THR A 274
ASP A 194
HIS A 198
GLY A 270
 ZN  A 401 (-3.3A)
None
ZN  A 401 (-2.5A)
ZN  A 401 (-3.2A)
None
 1.30A 5hm8H-4qgsA:
undetectable		 5hm8H-4qgsA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		4 / 5 GLU A  66
GLY A 100
SER A  96
GLY A  95
 None
 1.08A 5kprA-4qgsA:
undetectable		 5kprA-4qgsA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		3 / 3 HIS A 198
ASP A 194
HIS A 281
 ZN  A 401 (-3.2A)
ZN  A 401 (-2.5A)
ZN  A 401 (-3.3A)
 0.59A 5oexA-4qgsA:
undetectable		 5oexA-4qgsA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		3 / 3 HIS A 281
ASP A 194
HIS A 198
 ZN  A 401 (-3.3A)
ZN  A 401 (-2.5A)
ZN  A 401 (-3.2A)
 0.51A 5oexA-4qgsA:
undetectable		 5oexA-4qgsA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		3 / 3 HIS A 198
ASP A 194
HIS A 281
 ZN  A 401 (-3.2A)
ZN  A 401 (-2.5A)
ZN  A 401 (-3.3A)
 0.66A 5oexB-4qgsA:
undetectable		 5oexB-4qgsA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		3 / 3 HIS A 281
ASP A 194
HIS A 198
 ZN  A 401 (-3.3A)
ZN  A 401 (-2.5A)
ZN  A 401 (-3.2A)
 0.40A 5oexB-4qgsA:
undetectable		 5oexB-4qgsA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		3 / 3 HIS A 198
ASP A 194
HIS A 281
 ZN  A 401 (-3.2A)
ZN  A 401 (-2.5A)
ZN  A 401 (-3.3A)
 0.63A 5oexC-4qgsA:
undetectable		 5oexC-4qgsA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		3 / 3 HIS A 281
ASP A 194
HIS A 198
 ZN  A 401 (-3.3A)
ZN  A 401 (-2.5A)
ZN  A 401 (-3.2A)
 0.36A 5oexC-4qgsA:
undetectable		 5oexC-4qgsA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		3 / 3 HIS A 198
ASP A 194
HIS A 281
 ZN  A 401 (-3.2A)
ZN  A 401 (-2.5A)
ZN  A 401 (-3.3A)
 0.64A 5oexD-4qgsA:
undetectable		 5oexD-4qgsA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 4qgs ALCOHOL
DEHYDROGENASE YQHD
(Escherichia
coli) 		3 / 3 HIS A 281
ASP A 194
HIS A 198
 ZN  A 401 (-3.3A)
ZN  A 401 (-2.5A)
ZN  A 401 (-3.2A)
 0.37A 5oexD-4qgsA:
undetectable		 5oexD-4qgsA:
21.93