SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qgu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 4qgu GAMMA-INTERFERON-IND
UCIBLE PROTEIN 16
(Homo
sapiens) 		4 / 7 TYR A 218
ASN A 274
LEU A 245
LYS A 226
 None
 1.22A 3lslA-4qguA:
undetectable
3lslD-4qguA:
undetectable		 3lslA-4qguA:
19.41
3lslD-4qguA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 4qgu GAMMA-INTERFERON-IND
UCIBLE PROTEIN 16
(Homo
sapiens) 		4 / 7 TYR A 218
ASN A 274
LEU A 245
LYS A 226
 None
 1.27A 3lslA-4qguA:
undetectable
3lslD-4qguA:
undetectable		 3lslA-4qguA:
19.41
3lslD-4qguA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)		 4qgu GAMMA-INTERFERON-IND
UCIBLE PROTEIN 16
(Homo
sapiens) 		4 / 6 TYR A 218
ASN A 274
LEU A 245
LYS A 226
 None
 1.23A 3lslG-4qguA:
undetectable		 3lslG-4qguA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 4qgu GAMMA-INTERFERON-IND
UCIBLE PROTEIN 16
(Homo
sapiens) 		5 / 12 ILE A 386
TYR A 317
GLN A 310
LEU A 307
LEU A 378
 None
 1.19A 4qztA-4qguA:
undetectable		 4qztA-4qguA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 4qgu GAMMA-INTERFERON-IND
UCIBLE PROTEIN 16
(Homo
sapiens) 		4 / 6 ILE A 260
GLY A 255
ASN A 254
ILE A 258
 None
 0.88A 5j4nB-4qguA:
undetectable		 5j4nB-4qguA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 4qgu GAMMA-INTERFERON-IND
UCIBLE PROTEIN 16
(Homo
sapiens) 		4 / 5 ALA A 231
VAL A 209
LYS A 250
ILE A 259
 None
 0.96A 5of1A-4qguA:
undetectable		 5of1A-4qguA:
22.02