SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qhk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_1
(NEURAMINIDASE)		 4qhk UCA HEAVY CHAIN
(Homo
sapiens) 		3 / 3 ARG M  66
GLU M  46
TYR M  90
 None
 0.89A 3k37B-4qhkM:
undetectable		 3k37B-4qhkM:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 4qhk UCA HEAVY CHAIN
(Homo
sapiens) 		5 / 12 GLY M 174
SER M 172
VAL M 150
LEU M 178
PRO M 167
 None
 1.14A 5ergB-4qhkM:
undetectable		 5ergB-4qhkM:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_A_ACTA1231_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)		 4qhk UCA HEAVY CHAIN
(Homo
sapiens) 		3 / 3 ARG M  66
THR M  83
ASP M  86
 None
 0.96A 5g5gA-4qhkM:
undetectable
5g5gB-4qhkM:
undetectable		 5g5gA-4qhkM:
20.56
5g5gB-4qhkM:
22.36