SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qhs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRF_A_FOLA187_0
(DIHYDROFOLATE
REDUCTASE)		 4qhs FLAGELLAR REGULATORY
PROTEIN C
(Vibrio
cholerae) 		5 / 12 ILE A 227
LEU A 239
PHE A 201
ARG A 254
PHE A 219
 None
 1.08A 1drfA-4qhsA:
undetectable		 1drfA-4qhsA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4qhs FLAGELLAR REGULATORY
PROTEIN C
(Vibrio
cholerae) 		5 / 11 PHE A 284
LEU A 247
VAL A 246
PHE A 219
VAL A 267
 None
 1.13A 1q23L-4qhsA:
undetectable		 1q23L-4qhsA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4qhs FLAGELLAR REGULATORY
PROTEIN C
(Vibrio
cholerae) 		5 / 10 PHE A 284
LEU A 247
VAL A 246
PHE A 219
VAL A 267
 None
 1.03A 3u9fE-4qhsA:
undetectable		 3u9fE-4qhsA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4qhs FLAGELLAR REGULATORY
PROTEIN C
(Vibrio
cholerae) 		5 / 10 PHE A 284
LEU A 247
VAL A 246
PHE A 219
VAL A 267
 None
 1.10A 3u9fI-4qhsA:
undetectable		 3u9fI-4qhsA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4qhs FLAGELLAR REGULATORY
PROTEIN C
(Vibrio
cholerae) 		5 / 10 PHE A 284
LEU A 247
VAL A 246
PHE A 219
VAL A 267
 None
 1.06A 3u9fK-4qhsA:
undetectable		 3u9fK-4qhsA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4qhs FLAGELLAR REGULATORY
PROTEIN C
(Vibrio
cholerae) 		5 / 11 PHE A 284
LEU A 247
VAL A 246
PHE A 219
VAL A 267
 None
 1.05A 3u9fN-4qhsA:
undetectable
3u9fO-4qhsA:
undetectable		 3u9fN-4qhsA:
20.43
3u9fO-4qhsA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_P_CLMP221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4qhs FLAGELLAR REGULATORY
PROTEIN C
(Vibrio
cholerae) 		5 / 9 PHE A 284
LEU A 247
VAL A 246
PHE A 219
VAL A 267
 None
 1.10A 3u9fP-4qhsA:
undetectable		 3u9fP-4qhsA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4qhs FLAGELLAR REGULATORY
PROTEIN C
(Vibrio
cholerae) 		5 / 10 PHE A 284
LEU A 247
VAL A 246
PHE A 219
VAL A 267
 None
 1.09A 3u9fR-4qhsA:
undetectable		 3u9fR-4qhsA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4qhs FLAGELLAR REGULATORY
PROTEIN C
(Vibrio
cholerae) 		5 / 12 PHE A 284
LEU A 247
VAL A 246
PHE A 219
VAL A 267
 None
 1.09A 3u9fP-4qhsA:
undetectable
3u9fS-4qhsA:
undetectable		 3u9fP-4qhsA:
20.43
3u9fS-4qhsA:
20.43