SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qhz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4qhz PUTATIVE GLYCOSYL
HYDROLASE
(Parabacteroides
distasonis) 		4 / 7 TRP A  91
GLY A 249
GLN A 246
PHE A 257
 None
None
MG  A 302 (-2.7A)
None
 1.13A 2qx4A-4qhzA:
undetectable
2qx4B-4qhzA:
undetectable		 2qx4A-4qhzA:
21.24
2qx4B-4qhzA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ARC_A_LEUA1001_0
(LEUCINE--TRNA LIGASE)		 4qhz PUTATIVE GLYCOSYL
HYDROLASE
(Parabacteroides
distasonis) 		4 / 7 LEU A 151
TYR A 159
SER A 134
HIS A 248
 None
 1.37A 4arcA-4qhzA:
undetectable		 4arcA-4qhzA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H1N_A_CGEA505_1
(CYTOCHROME P450 2B4)		 4qhz PUTATIVE GLYCOSYL
HYDROLASE
(Parabacteroides
distasonis) 		5 / 11 ILE A 189
ILE A 140
THR A 227
ILE A 223
VAL A 208
 None
 1.18A 4h1nA-4qhzA:
undetectable		 4h1nA-4qhzA:
20.21