SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qi7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		4 / 8 SER A 485
ARG A 445
ILE A 494
LEU A 489
 None
 0.76A 1jg4A-4qi7A:
undetectable		 1jg4A-4qi7A:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JZS_A_MRCA1301_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 11 GLY A 184
GLY A  72
GLN A 182
LEU A  79
ILE A  80
 None
None
HEM  A 901 ( 4.7A)
HEM  A 901 (-3.2A)
None
 1.17A 1jzsA-4qi7A:
undetectable		 1jzsA-4qi7A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 GLY A 237
GLY A 238
VAL A 753
LEU A 419
LEU A 423
 FAD  A 902 (-4.5A)
FAD  A 902 ( 3.7A)
None
None
None
 0.97A 1mx1F-4qi7A:
2.0		 1mx1F-4qi7A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC439_0
(ADP-RIBOSYL CYCLASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		3 / 3 TRP A 333
PHE A 337
TRP A 341
 None
 1.16A 1r15C-4qi7A:
undetectable		 1r15C-4qi7A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF469_0
(ADP-RIBOSYL CYCLASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		3 / 3 TRP A 333
PHE A 337
TRP A 341
 None
 1.15A 1r15F-4qi7A:
undetectable		 1r15F-4qi7A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_G_NCAG479_0
(ADP-RIBOSYL CYCLASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		3 / 3 TRP A 333
PHE A 337
TRP A 341
 None
 1.16A 1r15G-4qi7A:
undetectable		 1r15G-4qi7A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_H_NCAH489_0
(ADP-RIBOSYL CYCLASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		3 / 3 TRP A 333
PHE A 337
TRP A 341
 None
 1.14A 1r15H-4qi7A:
undetectable		 1r15H-4qi7A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 LEU A 256
VAL A 440
ILE A 488
SER A 492
LEU A 732
 None
FAD  A 902 (-4.0A)
None
None
None
 1.14A 1s19A-4qi7A:
undetectable		 1s19A-4qi7A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1131_0
(FATTY ACID-BINDING
PROTEIN)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 10 LEU A 521
ASN A 731
ILE A 450
THR A 729
VAL A 453
 None
 1.34A 1tw4B-4qi7A:
1.2		 1tw4B-4qi7A:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		3 / 3 ASP A 711
ARG A 713
ASP A 721
 None
 0.87A 1vptA-4qi7A:
undetectable		 1vptA-4qi7A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		3 / 3 SER A 492
VAL A 476
LEU A 732
 None
 0.75A 1yajG-4qi7A:
undetectable		 1yajG-4qi7A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		3 / 3 TRP A 325
THR A 421
TYR A 422
 None
 0.71A 2a3aA-4qi7A:
undetectable		 2a3aA-4qi7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		3 / 3 TRP A 325
THR A 421
TYR A 422
 None
 0.67A 2a3aB-4qi7A:
undetectable		 2a3aB-4qi7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		3 / 3 TRP A 325
THR A 421
TYR A 422
 None
 0.75A 2a3bA-4qi7A:
undetectable		 2a3bA-4qi7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		4 / 8 PHE A 547
GLN A 572
TYR A 408
TYR A 410
 None
 1.11A 2aoxA-4qi7A:
undetectable		 2aoxA-4qi7A:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		4 / 8 THR A 729
GLY A 447
THR A 451
ILE A 450
 None
 0.78A 2f9wA-4qi7A:
undetectable
2f9wB-4qi7A:
undetectable		 2f9wA-4qi7A:
14.70
2f9wB-4qi7A:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_2
(PROTEASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 LEU A 489
GLY A 481
ALA A 480
ILE A 258
ILE A 488
 None
FAD  A 902 (-3.4A)
FAD  A 902 (-3.7A)
None
None
 0.98A 2nmyB-4qi7A:
undetectable		 2nmyB-4qi7A:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		3 / 3 ASP A 546
TYR A 548
LYS A 296
 None
 1.19A 2othA-4qi7A:
undetectable		 2othA-4qi7A:
9.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 GLY A 448
GLY A 728
GLY A 780
TRP A 803
LEU A 732
 None
None
PT  A 912 ( 4.6A)
None
None
 0.87A 2oxtC-4qi7A:
2.5		 2oxtC-4qi7A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_0
(UNCHARACTERIZED
PROTEIN PH0793)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 SER A 425
ILE A 320
ASP A 286
THR A 265
ASN A 321
 None
None
None
None
FAD  A 902 (-4.2A)
 1.29A 3a25A-4qi7A:
2.8		 3a25A-4qi7A:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 VAL A 638
SER A 632
LEU A 631
THR A 630
ASP A 498
 None
 1.22A 3a35B-4qi7A:
undetectable		 3a35B-4qi7A:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 VAL A 638
SER A 632
LEU A 631
THR A 630
ASP A 498
 None
 1.23A 3a3bA-4qi7A:
undetectable		 3a3bA-4qi7A:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 GLY A 448
GLY A 728
GLY A 780
TRP A 803
LEU A 732
 None
None
PT  A 912 ( 4.6A)
None
None
 0.91A 3eluA-4qi7A:
undetectable		 3eluA-4qi7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		6 / 12 GLY A 448
GLY A 728
GLY A 780
TRP A 803
THR A 729
LEU A 732
 None
None
PT  A 912 ( 4.6A)
None
None
None
 1.10A 3elwA-4qi7A:
2.7		 3elwA-4qi7A:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		4 / 8 ILE A 752
PRO A 748
ASN A 526
GLY A 481
 FAD  A 902 (-4.6A)
FAD  A 902 (-4.4A)
None
FAD  A 902 (-3.4A)
 0.91A 3em0B-4qi7A:
1.6		 3em0B-4qi7A:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 GLY A 448
GLY A 728
GLY A 780
TRP A 803
LEU A 732
 None
None
PT  A 912 ( 4.6A)
None
None
 0.95A 3embA-4qi7A:
2.5		 3embA-4qi7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 GLY A 448
GLY A 728
GLY A 780
TRP A 803
LEU A 732
 None
None
PT  A 912 ( 4.6A)
None
None
 0.89A 3gczA-4qi7A:
2.7		 3gczA-4qi7A:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_1
(PROTEASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 LEU A 489
GLY A 481
ALA A 480
ILE A 258
ILE A 488
 None
FAD  A 902 (-3.4A)
FAD  A 902 (-3.7A)
None
None
 0.97A 3ndtC-4qi7A:
undetectable		 3ndtC-4qi7A:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 LEU A 419
ALA A 239
GLY A 241
GLY A 315
ALA A 755
 None
FAD  A 902 (-3.3A)
None
None
None
 1.07A 3ou7B-4qi7A:
2.4		 3ou7B-4qi7A:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_3
(PROTEASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 LEU A 489
GLY A 481
ALA A 480
ILE A 258
ILE A 488
 None
FAD  A 902 (-3.4A)
FAD  A 902 (-3.7A)
None
None
 1.00A 3oxcB-4qi7A:
undetectable		 3oxcB-4qi7A:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T8N_D_EDTD135_0
(STEROID
DELTA-ISOMERASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 11 THR A 784
GLY A 785
GLY A 780
PRO A 781
ARG A 713
 None
None
PT  A 912 ( 4.6A)
PT  A 912 ( 4.0A)
None
 1.26A 3t8nD-4qi7A:
undetectable
3t8nF-4qi7A:
1.1		 3t8nD-4qi7A:
10.07
3t8nF-4qi7A:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_1
(PROTEASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 LEU A 489
GLY A 481
ALA A 480
ILE A 258
ILE A 488
 None
FAD  A 902 (-3.4A)
FAD  A 902 (-3.7A)
None
None
 0.97A 3tkgA-4qi7A:
undetectable		 3tkgA-4qi7A:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 9 ILE A 242
GLY A 240
THR A 318
GLY A 316
ARG A 459
 None
FAD  A 902 (-4.0A)
None
FAD  A 902 (-3.6A)
None
 1.07A 4acaB-4qi7A:
undetectable
4acaC-4qi7A:
undetectable		 4acaB-4qi7A:
21.29
4acaC-4qi7A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 9 ILE A 242
GLY A 241
THR A 318
GLY A 316
ARG A 459
 None
None
None
FAD  A 902 (-3.6A)
None
 1.27A 4acaB-4qi7A:
undetectable
4acaC-4qi7A:
undetectable		 4acaB-4qi7A:
21.29
4acaC-4qi7A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		4 / 5 GLY A 316
GLY A 317
ASN A 321
GLU A 259
 FAD  A 902 (-3.6A)
FAD  A 902 (-3.3A)
FAD  A 902 (-4.2A)
FAD  A 902 (-2.5A)
 1.21A 4fglC-4qi7A:
3.1		 4fglC-4qi7A:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_B_15UB402_1
(PROTHROMBIN)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 LEU A 125
ALA A 203
ILE A  80
GLY A  50
GLY A  33
 None
 1.04A 4hfpB-4qi7A:
undetectable		 4hfpB-4qi7A:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB304_1
(CHITOSANASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		4 / 5 TYR A 408
ILE A 577
THR A 406
HIS A 596
 None
 1.37A 4oltB-4qi7A:
undetectable		 4oltB-4qi7A:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 11 HIS A 268
SER A 264
THR A 749
GLY A 317
ALA A 319
 None
None
FAD  A 902 (-3.8A)
FAD  A 902 (-3.3A)
None
 1.24A 4qvlV-4qi7A:
undetectable
4qvlb-4qi7A:
undetectable		 4qvlV-4qi7A:
13.68
4qvlb-4qi7A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 11 HIS A 268
SER A 264
THR A 749
GLY A 317
ALA A 319
 None
None
FAD  A 902 (-3.8A)
FAD  A 902 (-3.3A)
None
 1.24A 4qvlH-4qi7A:
undetectable
4qvlN-4qi7A:
undetectable		 4qvlH-4qi7A:
13.68
4qvlN-4qi7A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 11 HIS A 268
SER A 264
THR A 749
GLY A 317
ALA A 319
 None
None
FAD  A 902 (-3.8A)
FAD  A 902 (-3.3A)
None
 1.24A 4qvmV-4qi7A:
undetectable
4qvmb-4qi7A:
undetectable		 4qvmV-4qi7A:
13.68
4qvmb-4qi7A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 11 HIS A 268
SER A 264
THR A 749
GLY A 317
ALA A 319
 None
None
FAD  A 902 (-3.8A)
FAD  A 902 (-3.3A)
None
 1.25A 4qvmH-4qi7A:
undetectable
4qvmN-4qi7A:
undetectable		 4qvmH-4qi7A:
13.68
4qvmN-4qi7A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 HIS A 268
SER A 264
THR A 749
GLY A 317
ALA A 319
 None
None
FAD  A 902 (-3.8A)
FAD  A 902 (-3.3A)
None
 1.24A 4qvnV-4qi7A:
undetectable
4qvnb-4qi7A:
undetectable		 4qvnV-4qi7A:
13.68
4qvnb-4qi7A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 HIS A 268
SER A 264
THR A 749
GLY A 317
ALA A 319
 None
None
FAD  A 902 (-3.8A)
FAD  A 902 (-3.3A)
None
 1.23A 4qvnH-4qi7A:
undetectable
4qvnN-4qi7A:
undetectable		 4qvnH-4qi7A:
13.68
4qvnN-4qi7A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 11 HIS A 268
SER A 264
THR A 749
GLY A 317
ALA A 319
 None
None
FAD  A 902 (-3.8A)
FAD  A 902 (-3.3A)
None
 1.24A 4qvpV-4qi7A:
undetectable
4qvpb-4qi7A:
undetectable		 4qvpV-4qi7A:
13.68
4qvpb-4qi7A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 11 HIS A 268
SER A 264
THR A 749
GLY A 317
ALA A 319
 None
None
FAD  A 902 (-3.8A)
FAD  A 902 (-3.3A)
None
 1.24A 4qvpH-4qi7A:
undetectable
4qvpN-4qi7A:
undetectable		 4qvpH-4qi7A:
13.68
4qvpN-4qi7A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 11 HIS A 268
SER A 264
THR A 749
GLY A 317
ALA A 319
 None
None
FAD  A 902 (-3.8A)
FAD  A 902 (-3.3A)
None
 1.24A 4qvqV-4qi7A:
undetectable
4qvqb-4qi7A:
undetectable		 4qvqV-4qi7A:
13.68
4qvqb-4qi7A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 11 HIS A 268
SER A 264
THR A 749
GLY A 317
ALA A 319
 None
None
FAD  A 902 (-3.8A)
FAD  A 902 (-3.3A)
None
 1.24A 4qvqH-4qi7A:
undetectable
4qvqN-4qi7A:
undetectable		 4qvqH-4qi7A:
13.68
4qvqN-4qi7A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 11 HIS A 268
SER A 264
THR A 749
GLY A 317
ALA A 319
 None
None
FAD  A 902 (-3.8A)
FAD  A 902 (-3.3A)
None
 1.26A 4qw0V-4qi7A:
undetectable
4qw0b-4qi7A:
undetectable		 4qw0V-4qi7A:
13.68
4qw0b-4qi7A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 11 HIS A 268
SER A 264
THR A 749
GLY A 317
ALA A 319
 None
None
FAD  A 902 (-3.8A)
FAD  A 902 (-3.3A)
None
 1.25A 4qw0H-4qi7A:
undetectable
4qw0N-4qi7A:
undetectable		 4qw0H-4qi7A:
13.68
4qw0N-4qi7A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 11 HIS A 268
SER A 264
THR A 749
GLY A 317
ALA A 319
 None
None
FAD  A 902 (-3.8A)
FAD  A 902 (-3.3A)
None
 1.24A 4qw1V-4qi7A:
undetectable
4qw1b-4qi7A:
undetectable		 4qw1V-4qi7A:
13.68
4qw1b-4qi7A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 11 HIS A 268
SER A 264
THR A 749
GLY A 317
ALA A 319
 None
None
FAD  A 902 (-3.8A)
FAD  A 902 (-3.3A)
None
 1.24A 4qw1H-4qi7A:
undetectable
4qw1N-4qi7A:
undetectable		 4qw1H-4qi7A:
13.68
4qw1N-4qi7A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA303_1
(CHITOSANASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		4 / 6 TYR A 408
ILE A 577
THR A 406
HIS A 596
 None
 1.37A 4qwpA-4qi7A:
undetectable		 4qwpA-4qi7A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 11 HIS A 268
SER A 264
THR A 749
GLY A 317
ALA A 319
 None
None
FAD  A 902 (-3.8A)
FAD  A 902 (-3.3A)
None
 1.24A 4qwuH-4qi7A:
undetectable
4qwuN-4qi7A:
undetectable		 4qwuH-4qi7A:
13.68
4qwuN-4qi7A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 THR A 124
SER A 117
GLY A  50
PHE A   7
GLY A  13
 NAG  A 903 (-3.9A)
NAG  A 903 ( 4.6A)
None
None
None
 1.36A 4uinH-4qi7A:
2.8
4uinL-4qi7A:
2.6		 4uinH-4qi7A:
15.47
4uinL-4qi7A:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 11 HIS A 268
SER A 264
THR A 749
GLY A 317
ALA A 319
 None
None
FAD  A 902 (-3.8A)
FAD  A 902 (-3.3A)
None
 1.21A 5bxnV-4qi7A:
undetectable
5bxnb-4qi7A:
undetectable		 5bxnV-4qi7A:
13.70
5bxnb-4qi7A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 11 HIS A 268
SER A 264
THR A 749
GLY A 317
ALA A 319
 None
None
FAD  A 902 (-3.8A)
FAD  A 902 (-3.3A)
None
 1.21A 5bxnH-4qi7A:
undetectable
5bxnN-4qi7A:
undetectable		 5bxnH-4qi7A:
13.70
5bxnN-4qi7A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 11 HIS A 268
SER A 264
THR A 749
GLY A 317
ALA A 319
 None
None
FAD  A 902 (-3.8A)
FAD  A 902 (-3.3A)
None
 1.25A 5cz7H-4qi7A:
undetectable
5cz7N-4qi7A:
undetectable		 5cz7H-4qi7A:
13.68
5cz7N-4qi7A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 11 HIS A 268
SER A 264
THR A 749
GLY A 317
ALA A 319
 None
None
FAD  A 902 (-3.8A)
FAD  A 902 (-3.3A)
None
 1.24A 5d0xH-4qi7A:
undetectable
5d0xN-4qi7A:
undetectable		 5d0xH-4qi7A:
13.68
5d0xN-4qi7A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 10 PRO A 579
LEU A 382
VAL A 668
ILE A 537
LEU A 671
 None
None
NAG  A 908 ( 4.8A)
None
None
 1.13A 5ienB-4qi7A:
undetectable		 5ienB-4qi7A:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 LEU A 125
LEU A 153
LEU A  70
PHE A 127
LEU A  36
 None
 1.21A 5iepA-4qi7A:
undetectable		 5iepA-4qi7A:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 ASP A 711
ARG A 713
LEU A 521
SER A 738
GLY A 708
 None
 1.37A 5il1A-4qi7A:
undetectable		 5il1A-4qi7A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 HIS A 268
SER A 264
THR A 749
GLY A 317
ALA A 319
 None
None
FAD  A 902 (-3.8A)
FAD  A 902 (-3.3A)
None
 1.25A 5l5zV-4qi7A:
undetectable
5l5zb-4qi7A:
undetectable		 5l5zV-4qi7A:
13.68
5l5zb-4qi7A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 HIS A 268
SER A 264
THR A 749
GLY A 317
ALA A 319
 None
None
FAD  A 902 (-3.8A)
FAD  A 902 (-3.3A)
None
 1.24A 5l5zH-4qi7A:
undetectable
5l5zN-4qi7A:
undetectable		 5l5zH-4qi7A:
13.68
5l5zN-4qi7A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 11 HIS A 268
SER A 264
THR A 749
GLY A 317
ALA A 319
 None
None
FAD  A 902 (-3.8A)
FAD  A 902 (-3.3A)
None
 1.25A 5l66V-4qi7A:
undetectable
5l66b-4qi7A:
undetectable		 5l66V-4qi7A:
13.68
5l66b-4qi7A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 11 HIS A 268
SER A 264
THR A 749
GLY A 317
ALA A 319
 None
None
FAD  A 902 (-3.8A)
FAD  A 902 (-3.3A)
None
 1.24A 5l66H-4qi7A:
undetectable
5l66N-4qi7A:
undetectable		 5l66H-4qi7A:
13.68
5l66N-4qi7A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MSD_A_BEZA1202_0
(CARBOXYLIC ACID
REDUCTASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		4 / 5 ILE A 577
PHE A 375
SER A 404
ALA A 599
 None
 1.23A 5msdA-4qi7A:
undetectable		 5msdA-4qi7A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		3 / 3 THR A 745
HIS A 530
ASN A 747
 None
None
FAD  A 902 (-3.8A)
 0.81A 5n4tA-4qi7A:
undetectable		 5n4tA-4qi7A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_A_SAMA401_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 GLY A 236
GLY A 241
ILE A 467
VAL A 255
LEU A 256
 FAD  A 902 (-3.5A)
None
None
None
None
 1.09A 5wyqA-4qi7A:
undetectable		 5wyqA-4qi7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 GLU A 757
VAL A 753
PRO A 418
HIS A 268
PHE A 432
 None
 1.21A 5xioA-4qi7A:
undetectable		 5xioA-4qi7A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA402_0
(CYCLIN-G-ASSOCIATED
KINASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 11 ASP A 231
SER A 254
VAL A 224
ILE A 467
ILE A 258
 None
 1.31A 5y80A-4qi7A:
undetectable		 5y80A-4qi7A:
6.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_1
(NS3 PROTEASE)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 9 GLY A 348
ILE A 763
LEU A 764
LYS A 762
ASP A 246
 None
 1.24A 6c2mC-4qi7A:
undetectable		 6c2mC-4qi7A:
7.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 4qi7 CELLOBIOSE
DEHYDROGENASE
(Neurospora
crassa) 		5 / 12 HIS A 268
SER A 264
THR A 749
GLY A 317
ALA A 319
 None
None
FAD  A 902 (-3.8A)
FAD  A 902 (-3.3A)
None
 1.24A 6hwdH-4qi7A:
undetectable
6hwdN-4qi7A:
undetectable		 6hwdH-4qi7A:
9.02
6hwdN-4qi7A:
10.16