SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qiu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4qiu NITRONATE
MONOOXYGENASE FAMILY
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 ALA A 227
GLY A 217
ALA A 228
THR A 198
 None
FMN  A 401 (-3.3A)
None
None
 0.69A 1gtnI-4qiuA:
undetectable
1gtnJ-4qiuA:
undetectable		 1gtnI-4qiuA:
14.39
1gtnJ-4qiuA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 4qiu NITRONATE
MONOOXYGENASE FAMILY
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 4 LEU A 258
VAL A 243
CYH A 245
ALA A 338
 None
 1.26A 1mz9E-4qiuA:
undetectable		 1mz9E-4qiuA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 4qiu NITRONATE
MONOOXYGENASE FAMILY
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  18
GLN A  17
LEU A  38
LEU A 153
CYH A 155
 FMN  A 401 (-3.5A)
None
None
None
None
 1.45A 2oaxF-4qiuA:
undetectable		 2oaxF-4qiuA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 4qiu NITRONATE
MONOOXYGENASE FAMILY
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 4 LEU A   9
ALA A 235
VAL A 214
PRO A 212
 None
 1.17A 3gv1B-4qiuA:
undetectable		 3gv1B-4qiuA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_0
(NEURAMINIDASE)		 4qiu NITRONATE
MONOOXYGENASE FAMILY
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 GLU A 348
ARG A 334
ARG A 343
ALA A  35
GLU A 347
 None
 1.39A 3k37A-4qiuA:
undetectable		 3k37A-4qiuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_0
(NEURAMINIDASE)		 4qiu NITRONATE
MONOOXYGENASE FAMILY
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 GLU A 348
ARG A 334
ARG A 343
ALA A  35
GLU A 347
 None
 1.39A 3k37B-4qiuA:
undetectable		 3k37B-4qiuA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_A_PQNA846_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 4qiu NITRONATE
MONOOXYGENASE FAMILY
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 ARG A 343
ALA A 339
LEU A 342
GLY A  36
ALA A 180
 None
None
None
None
FMN  A 401 (-3.3A)
 1.40A 4fe1A-4qiuA:
undetectable
4fe1J-4qiuA:
undetectable		 4fe1A-4qiuA:
20.03
4fe1J-4qiuA:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 4qiu NITRONATE
MONOOXYGENASE FAMILY
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 9 VAL A  32
ALA A  31
GLY A 239
PHE A 242
SER A  24
 None
None
FMN  A 401 (-3.3A)
None
None
 1.03A 4mm5A-4qiuA:
undetectable		 4mm5A-4qiuA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 4qiu NITRONATE
MONOOXYGENASE FAMILY
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 9 VAL A  32
ALA A  31
GLY A 239
PHE A 242
SER A  24
 None
None
FMN  A 401 (-3.3A)
None
None
 1.11A 4mmfA-4qiuA:
undetectable		 4mmfA-4qiuA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 4qiu NITRONATE
MONOOXYGENASE FAMILY
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 9 VAL A  32
ALA A  31
GLY A 239
PHE A 242
SER A  24
 None
None
FMN  A 401 (-3.3A)
None
None
 1.09A 4mmfB-4qiuA:
undetectable		 4mmfB-4qiuA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 4qiu NITRONATE
MONOOXYGENASE FAMILY
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 326
GLY A 181
ARG A 255
GLY A 329
LEU A 244
 None
FMN  A 401 (-3.7A)
None
None
None
 1.10A 5gwxA-4qiuA:
undetectable		 5gwxA-4qiuA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 4qiu NITRONATE
MONOOXYGENASE FAMILY
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 GLY A 135
PHE A 132
HIS A 133
SER A 111
 None
None
FMN  A 401 (-3.3A)
None
 1.04A 6hu9S-4qiuA:
undetectable
6hu9q-4qiuA:
undetectable		 6hu9S-4qiuA:
12.17
6hu9q-4qiuA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 4qiu NITRONATE
MONOOXYGENASE FAMILY
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 9 ILE A  41
ALA A  29
GLY A  39
LEU A  38
GLY A 239
 None
None
None
None
FMN  A 401 (-3.3A)
 1.27A 6nm4B-4qiuA:
undetectable		 6nm4B-4qiuA:
17.88