SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qkw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4qkw MUSCLE-RELATED
COILED-COIL PROTEIN
(Danio
rerio) 		4 / 6 GLY A  37
ILE A  35
GLN A  39
SER A  32
 None
 0.77A 1rs7B-4qkwA:
undetectable		 1rs7B-4qkwA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_1
(DIHYDROFOLATE
REDUCTASE)		 4qkw MUSCLE-RELATED
COILED-COIL PROTEIN
(Danio
rerio) 		3 / 3 GLU A  93
GLN A 101
ARG A 104
 None
 0.62A 2w3bB-4qkwA:
undetectable		 2w3bB-4qkwA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_ACTA803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4qkw MUSCLE-RELATED
COILED-COIL PROTEIN
(Danio
rerio) 		4 / 6 GLY A  37
ILE A  35
GLN A  39
SER A  32
 None
 0.86A 4kcnA-4qkwA:
undetectable		 4kcnA-4qkwA:
14.05