SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ql0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_1
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 4ql0 FILAMENTOUS
HEMAGGLUTININ
TRANSPORTER PROTEIN
FHAC
(Bordetella
pertussis) 		4 / 7 TYR A 447
THR A 527
SER A 529
TYR A 547
 None
 1.19A 1eiiA-4ql0A:
1.5		 1eiiA-4ql0A:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 4ql0 FILAMENTOUS
HEMAGGLUTININ
TRANSPORTER PROTEIN
FHAC
(Bordetella
pertussis) 		3 / 3 ARG A 523
SER A 529
TYR A 528
 None
 0.57A 1x70A-4ql0A:
2.5		 1x70A-4ql0A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA501_1
(CYTOCHROME P450 2B4)		 4ql0 FILAMENTOUS
HEMAGGLUTININ
TRANSPORTER PROTEIN
FHAC
(Bordetella
pertussis) 		4 / 7 LEU A 105
GLY A 109
THR A 169
ILE A 190
 None
PEG  A 602 ( 4.6A)
None
None
 0.75A 2bdmA-4ql0A:
undetectable		 2bdmA-4ql0A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		 4ql0 FILAMENTOUS
HEMAGGLUTININ
TRANSPORTER PROTEIN
FHAC
(Bordetella
pertussis) 		3 / 3 ASN A 339
TYR A 353
SER A 307
 None
 0.92A 2gvcB-4ql0A:
undetectable		 2gvcB-4ql0A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 4ql0 FILAMENTOUS
HEMAGGLUTININ
TRANSPORTER PROTEIN
FHAC
(Bordetella
pertussis) 		3 / 3 ASN A 339
TYR A 353
SER A 307
 None
 0.92A 2gvcE-4ql0A:
undetectable		 2gvcE-4ql0A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 4ql0 FILAMENTOUS
HEMAGGLUTININ
TRANSPORTER PROTEIN
FHAC
(Bordetella
pertussis) 		5 / 12 SER A 157
ASP A 171
GLN A 174
ALA A 175
ILE A 179
 None
1PE  A 607 (-3.4A)
P6G  A 609 (-3.7A)
None
None
 1.19A 3a35B-4ql0A:
undetectable		 3a35B-4ql0A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4ql0 FILAMENTOUS
HEMAGGLUTININ
TRANSPORTER PROTEIN
FHAC
(Bordetella
pertussis) 		5 / 10 TYR A 452
ILE A 506
VAL A 493
GLY A 510
PRO A 536
 None
 1.20A 3elzC-4ql0A:
2.2		 3elzC-4ql0A:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 4ql0 FILAMENTOUS
HEMAGGLUTININ
TRANSPORTER PROTEIN
FHAC
(Bordetella
pertussis) 		3 / 3 LEU A 201
TRP A 162
GLY A 161
 None
 0.75A 3l35A-4ql0A:
undetectable
3l35H-4ql0A:
undetectable		 3l35A-4ql0A:
11.37
3l35H-4ql0A:
2.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 4ql0 FILAMENTOUS
HEMAGGLUTININ
TRANSPORTER PROTEIN
FHAC
(Bordetella
pertussis) 		3 / 3 LEU A 201
TRP A 162
GLY A 161
 None
 0.74A 3l35B-4ql0A:
undetectable
3l35K-4ql0A:
undetectable		 3l35B-4ql0A:
11.37
3l35K-4ql0A:
2.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 4ql0 FILAMENTOUS
HEMAGGLUTININ
TRANSPORTER PROTEIN
FHAC
(Bordetella
pertussis) 		4 / 8 TYR A 452
VAL A 449
GLY A 510
GLY A 494
 None
 0.78A 3n9jB-4ql0A:
undetectable		 3n9jB-4ql0A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 4ql0 FILAMENTOUS
HEMAGGLUTININ
TRANSPORTER PROTEIN
FHAC
(Bordetella
pertussis) 		4 / 6 THR A 279
ARG A 280
LEU A 281
ASP A 282
 None
P6G  A 609 (-2.8A)
None
PGE  A 601 ( 4.6A)
 1.07A 5tdzA-4ql0A:
undetectable		 5tdzA-4ql0A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4ql0 FILAMENTOUS
HEMAGGLUTININ
TRANSPORTER PROTEIN
FHAC
(Bordetella
pertussis) 		3 / 3 LEU A 146
ASN A 245
LEU A 205
 None
 0.60A 6exiD-4ql0A:
undetectable		 6exiD-4ql0A:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FDY_U_DB8U302_1
(-)		 4ql0 FILAMENTOUS
HEMAGGLUTININ
TRANSPORTER PROTEIN
FHAC
(Bordetella
pertussis) 		5 / 9 LEU A 496
VAL A 443
PHE A 428
SER A 406
LEU A 426
 None
 1.41A 6fdyU-4ql0A:
1.0		 6fdyU-4ql0A:
19.28