SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ql9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 4ql9 ALKYLHYDROPEROXIDE
REDUCTASE SUBUNIT C
(Escherichia
coli) 		4 / 8 LEU A 149
PRO A 127
VAL A  66
GLY A  65
 None
 0.93A 1hrkA-4ql9A:
2.2		 1hrkA-4ql9A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 4ql9 ALKYLHYDROPEROXIDE
REDUCTASE SUBUNIT C
(Escherichia
coli) 		4 / 8 LEU A 149
PRO A 127
VAL A  66
GLY A  65
 None
 0.95A 1hrkB-4ql9A:
undetectable		 1hrkB-4ql9A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)		 4ql9 ALKYLHYDROPEROXIDE
REDUCTASE SUBUNIT C
(Escherichia
coli) 		3 / 3 ASP A  42
THR A  44
GLU A 139
 None
 0.52A 1pj7A-4ql9A:
2.4		 1pj7A-4ql9A:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4ql9 ALKYLHYDROPEROXIDE
REDUCTASE SUBUNIT C
(Escherichia
coli) 		4 / 8 LEU A 149
PRO A 127
VAL A  66
GLY A  65
 None
 0.94A 2po5A-4ql9A:
2.3		 2po5A-4ql9A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 4ql9 ALKYLHYDROPEROXIDE
REDUCTASE SUBUNIT C
(Escherichia
coli) 		4 / 6 SER A 146
ALA A 145
HIS A  57
ASP A  56
 None
 1.25A 3aruA-4ql9A:
undetectable		 3aruA-4ql9A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWQ_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4ql9 ALKYLHYDROPEROXIDE
REDUCTASE SUBUNIT C
(Escherichia
coli) 		5 / 12 ALA A  90
TYR A  39
ASP A  42
SER A  86
ILE A  92
 None
 1.23A 3vwqA-4ql9A:
undetectable		 3vwqA-4ql9A:
19.59