SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qlj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_A_HISA450_0
(HISTIDYL-TRNA
SYNTHETASE)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		5 / 10 GLU A 440
TYR A 131
GLN A  29
TYR A 315
GLY A 386
 CTT  A1001 (-2.7A)
None
CTT  A1001 (-3.0A)
CTT  A1001 (-4.2A)
None
 1.50A 1httA-4qljA:
undetectable		 1httA-4qljA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		5 / 12 ILE A 373
ALA A 259
GLY A 269
LEU A 287
TYR A 377
 None
 1.14A 1kiaC-4qljA:
undetectable		 1kiaC-4qljA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		4 / 7 GLY A 351
ILE A 361
VAL A 362
PRO A 363
 None
 1.06A 1rxcF-4qljA:
undetectable		 1rxcF-4qljA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		4 / 7 GLY A 351
ILE A 361
VAL A 362
PRO A 363
 None
 1.07A 1rxcL-4qljA:
undetectable		 1rxcL-4qljA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SKX_A_RFPA1_2
(ORPHAN NUCLEAR
RECEPTOR PXR)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		4 / 5 PHE A 431
LEU A 474
MET A  77
LEU A 118
 None
 1.09A 1skxA-4qljA:
undetectable		 1skxA-4qljA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		4 / 5 LEU A 435
PRO A 463
VAL A 452
ILE A 451
 None
 0.95A 2aoiB-4qljA:
undetectable		 2aoiB-4qljA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_1
(POL PROTEIN)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		5 / 11 ALA A  84
ASP A  83
GLY A 429
ILE A 384
PHE A 172
 None
 0.97A 2fxdA-4qljA:
undetectable		 2fxdA-4qljA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_1
(POL PROTEIN)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		5 / 11 GLY A  22
ALA A  84
ASP A  83
ILE A 384
PHE A 172
 None
 1.11A 2fxdA-4qljA:
undetectable		 2fxdA-4qljA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMA_A_SAMA375_0
(PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		5 / 11 GLY A 386
ASN A 127
THR A 385
GLY A 311
PHE A 174
 None
 1.28A 2hmaA-4qljA:
1.4		 2hmaA-4qljA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		4 / 7 ALA A 221
ALA A 220
ALA A 224
GLN A 299
 None
 0.72A 3a2qA-4qljA:
undetectable		 3a2qA-4qljA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		4 / 8 VAL A 241
GLY A 386
TYR A 315
HIS A 130
 None
None
CTT  A1001 (-4.2A)
CTT  A1001 (-4.1A)
 0.98A 3af0A-4qljA:
undetectable		 3af0A-4qljA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_4
(HIV-1 PROTEASE)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		4 / 4 LEU A 242
ASP A 308
VAL A 383
THR A 385
 None
 1.24A 3cyxB-4qljA:
undetectable		 3cyxB-4qljA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		3 / 3 TYR A 468
ASP A 403
HIS A 462
 CTT  A1002 (-3.8A)
None
None
 0.92A 3e23A-4qljA:
undetectable		 3e23A-4qljA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		4 / 7 PHE A  15
PHE A  21
TYR A 430
GLY A 311
 None
 1.00A 3em0B-4qljA:
undetectable		 3em0B-4qljA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		4 / 7 VAL A  24
TYR A 315
THR A 316
GLY A 386
 None
CTT  A1001 (-4.2A)
None
None
 0.94A 3gssA-4qljA:
undetectable		 3gssA-4qljA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		4 / 7 VAL A  24
TYR A 315
THR A 316
GLY A 386
 None
CTT  A1001 (-4.2A)
None
None
 1.00A 3gssB-4qljA:
undetectable		 3gssB-4qljA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA279_0
(UNIVERSAL STRESS
PROTEIN)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		4 / 4 SER A 356
SER A 443
THR A 446
SER A 447
 None
 1.39A 3loqA-4qljA:
1.5		 3loqA-4qljA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_A_NCAA1359_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		4 / 7 TRP A 337
ASN A 245
TYR A 247
TYR A 333
 None
CTT  A1001 (-3.6A)
None
None
 1.49A 4a3uA-4qljA:
13.4		 4a3uA-4qljA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		4 / 7 GLY A  32
ASP A  61
GLY A  60
HIS A  49
 None
 0.76A 4c5nA-4qljA:
2.1		 4c5nA-4qljA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		4 / 8 GLY A  32
ASP A  61
GLY A  60
HIS A  49
 None
 0.74A 4c5nC-4qljA:
undetectable		 4c5nC-4qljA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		3 / 3 ASP A 132
TRP A 433
SER A  88
 None
CTT  A1001 (-3.5A)
None
 0.99A 4lrhB-4qljA:
undetectable		 4lrhB-4qljA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		3 / 3 ASP A 132
TRP A 433
SER A  88
 None
CTT  A1001 (-3.5A)
None
 1.06A 4lrhF-4qljA:
undetectable		 4lrhF-4qljA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_2
(PROTEASE)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		5 / 12 ILE A 122
GLY A  22
PRO A 463
VAL A 452
ILE A 451
 None
 0.96A 4q5mA-4qljA:
undetectable		 4q5mA-4qljA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		4 / 6 GLY A 388
PHE A 470
ILE A 451
PHE A  82
 None
 1.05A 4qogA-4qljA:
undetectable
4qogB-4qljA:
undetectable		 4qogA-4qljA:
19.01
4qogB-4qljA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		3 / 3 ASN A 175
PHE A 431
TYR A  85
 CTT  A1001 (-3.1A)
None
None
 0.67A 4u15A-4qljA:
undetectable		 4u15A-4qljA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		5 / 12 TYR A  70
TYR A  28
ASP A  65
ALA A  63
TYR A 445
 None
None
ZN  A1003 (-2.1A)
None
None
 1.39A 4ymgB-4qljA:
undetectable		 4ymgB-4qljA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		3 / 3 TYR A 131
TYR A  85
SER A 434
 None
 0.88A 5iktB-4qljA:
undetectable		 5iktB-4qljA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 4qlj BETA-GLUCOSIDASE 7
(Oryza
sativa) 		4 / 5 LEU A 414
TYR A 413
LEU A 417
TYR A 430
 None
 1.47A 5ki6A-4qljA:
undetectable		 5ki6A-4qljA:
20.55