SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qlp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 4qlp ALANINE AND PROLINE
RICH PROTEIN,
TUBERCULOSIS
NECROTIZING TOXIN
(TNT)
(Mycobacterium
tuberculosis) 		5 / 12 ARG B 713
GLY B 813
ASN B 726
VAL B 784
PHE B 696
 None
 1.17A 2zzmA-4qlpB:
undetectable		 2zzmA-4qlpB:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 4qlp ALANINE AND PROLINE
RICH PROTEIN,
TUBERCULOSIS
NECROTIZING TOXIN
(TNT)
(Mycobacterium
tuberculosis) 		5 / 12 ARG B 713
PRO B 812
ASN B 726
VAL B 784
PHE B 696
 None
 1.15A 2zzmA-4qlpB:
undetectable		 2zzmA-4qlpB:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 4qlp ALANINE AND PROLINE
RICH PROTEIN,
TUBERCULOSIS
NECROTIZING TOXIN
(TNT)
(Mycobacterium
tuberculosis) 		5 / 12 ARG B 713
GLY B 813
ASN B 726
VAL B 784
PHE B 696
 None
 1.25A 2zznA-4qlpB:
undetectable		 2zznA-4qlpB:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 4qlp ALANINE AND PROLINE
RICH PROTEIN,
TUBERCULOSIS
NECROTIZING TOXIN
(TNT)
(Mycobacterium
tuberculosis) 		5 / 12 ARG B 713
PRO B 812
ASN B 726
VAL B 784
PHE B 696
 None
 1.21A 2zznA-4qlpB:
undetectable		 2zznA-4qlpB:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 4qlp ALANINE AND PROLINE
RICH PROTEIN,
TUBERCULOSIS
NECROTIZING TOXIN
(TNT)
(Mycobacterium
tuberculosis) 		4 / 6 PHE B 671
PHE B 696
TYR B 710
THR B 785
 None
 1.14A 3lb3A-4qlpB:
undetectable		 3lb3A-4qlpB:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 4qlp ALANINE AND PROLINE
RICH PROTEIN,
TUBERCULOSIS
NECROTIZING TOXIN
(TNT)
(Mycobacterium
tuberculosis) 		4 / 6 PHE B 671
PHE B 696
TYR B 710
THR B 785
 None
 1.09A 3lb3B-4qlpB:
undetectable		 3lb3B-4qlpB:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 4qlp ALANINE AND PROLINE
RICH PROTEIN,
TUBERCULOSIS
NECROTIZING TOXIN
(TNT)
(Mycobacterium
tuberculosis) 		3 / 3 ASN B 731
ALA B 733
ARG B 738
 None
 0.86A 3tj7C-4qlpB:
undetectable
3tj7D-4qlpB:
undetectable		 3tj7C-4qlpB:
18.69
3tj7D-4qlpB:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4qlp ALANINE AND PROLINE
RICH PROTEIN,
TUBERCULOSIS
NECROTIZING TOXIN
(TNT)
(Mycobacterium
tuberculosis) 		4 / 7 ILE B 739
TYR B 751
HIS B 771
PHE B 747
 None
 0.94A 4a97H-4qlpB:
undetectable		 4a97H-4qlpB:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)		 4qlp ALANINE AND PROLINE
RICH PROTEIN,
TUBERCULOSIS
NECROTIZING TOXIN
(TNT)
(Mycobacterium
tuberculosis) 		4 / 6 GLY B 721
VAL B 717
PRO B 719
GLU B 655
 None
 0.83A 4dxuA-4qlpB:
undetectable		 4dxuA-4qlpB:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4qlp ALANINE AND PROLINE
RICH PROTEIN,
TUBERCULOSIS
NECROTIZING TOXIN
(TNT)
(Mycobacterium
tuberculosis) 		4 / 7 TYR B 705
ARG B 709
GLY B 702
ARG B 698
 None
 0.97A 4fgzA-4qlpB:
undetectable		 4fgzA-4qlpB:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 4qlp ALANINE AND PROLINE
RICH PROTEIN,
TUBERCULOSIS
NECROTIZING TOXIN
(TNT)
(Mycobacterium
tuberculosis) 		5 / 9 ALA B 686
GLN B 687
PRO B 695
LEU B 787
ILE B 681
 None
 1.46A 5i73A-4qlpB:
undetectable		 5i73A-4qlpB:
15.58