SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qlx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_A_RBFA300_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4qlx NITROREDUCTASE
FAMILY PROTEIN
(Lactobacillus
plantarum) 		5 / 11 GLY A 195
SER A  86
ILE A 192
HIS A 160
ALA A 164
 None
 1.36A 2a58A-4qlxA:
undetectable
2a58E-4qlxA:
undetectable		 2a58A-4qlxA:
22.27
2a58E-4qlxA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_D_RBFD303_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 4qlx NITROREDUCTASE
FAMILY PROTEIN
(Lactobacillus
plantarum) 		5 / 11 ILE A 192
HIS A 160
ALA A 164
GLY A 195
SER A  86
 None
 1.37A 2a58C-4qlxA:
undetectable
2a58D-4qlxA:
undetectable		 2a58C-4qlxA:
22.27
2a58D-4qlxA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_1
(PROTEASE)		 4qlx NITROREDUCTASE
FAMILY PROTEIN
(Lactobacillus
plantarum) 		5 / 11 ALA A  87
GLY A 191
ILE A  91
ALA A 157
ILE A 194
 None
 1.12A 2idwA-4qlxA:
undetectable		 2idwA-4qlxA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 4qlx NITROREDUCTASE
FAMILY PROTEIN
(Lactobacillus
plantarum) 		4 / 6 ILE A  88
TYR A  79
MET A 175
ILE A 170
 None
 1.07A 3eteA-4qlxA:
undetectable
3eteE-4qlxA:
undetectable		 3eteA-4qlxA:
18.84
3eteE-4qlxA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 4qlx NITROREDUCTASE
FAMILY PROTEIN
(Lactobacillus
plantarum) 		4 / 5 ILE A  88
TYR A  79
MET A 175
ILE A 170
 None
 1.05A 3eteB-4qlxA:
undetectable
3eteC-4qlxA:
undetectable		 3eteB-4qlxA:
18.84
3eteC-4qlxA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 4qlx NITROREDUCTASE
FAMILY PROTEIN
(Lactobacillus
plantarum) 		4 / 7 MET A 175
ILE A 170
ILE A  88
TYR A  79
 None
 1.07A 3eteD-4qlxA:
undetectable
3eteF-4qlxA:
undetectable		 3eteD-4qlxA:
18.84
3eteF-4qlxA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4qlx NITROREDUCTASE
FAMILY PROTEIN
(Lactobacillus
plantarum) 		4 / 6 VAL A 100
SER A  55
ILE A  91
PHE A  58
 None
 1.05A 5jw1A-4qlxA:
undetectable		 5jw1A-4qlxA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OAJ_E_TKTE601_1
()		 4qlx NITROREDUCTASE
FAMILY PROTEIN
(Lactobacillus
plantarum) 		4 / 8 GLU A 131
CYH A  51
TYR A 101
PHE A 137
 None
KTC  A 302 (-3.4A)
None
KTC  A 302 (-4.8A)
 1.33A 5oajD-4qlxA:
undetectable
5oajE-4qlxA:
undetectable		 5oajD-4qlxA:
18.49
5oajE-4qlxA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4qlx NITROREDUCTASE
FAMILY PROTEIN
(Lactobacillus
plantarum) 		3 / 3 VAL A  89
VAL A  60
GLN A  38
 None
 0.62A 5qgmA-4qlxA:
undetectable		 5qgmA-4qlxA:
21.27