SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qma'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_B_DVAB8_0
(GRAMICIDIN A)		 4qma CYSTEINE DIOXYGENASE
TYPE I
(Cupriavidus
pinatubonensis) 		3 / 3 VAL A  98
VAL A 139
TRP A  99
 None
None
EDO  A 308 (-3.9A)
 0.67A 1av2A-4qmaA:
undetectable
1av2B-4qmaA:
undetectable		 1av2A-4qmaA:
9.20
1av2B-4qmaA:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB8_0
(GRAMICIDIN D)		 4qma CYSTEINE DIOXYGENASE
TYPE I
(Cupriavidus
pinatubonensis) 		3 / 3 VAL A  98
VAL A 139
TRP A  99
 None
None
EDO  A 308 (-3.9A)
 0.72A 1w5uA-4qmaA:
undetectable
1w5uB-4qmaA:
undetectable		 1w5uA-4qmaA:
9.20
1w5uB-4qmaA:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 4qma CYSTEINE DIOXYGENASE
TYPE I
(Cupriavidus
pinatubonensis) 		3 / 3 PHE A  83
ARG A 130
ASN A 151
 OXY  A 302 (-4.5A)
None
None
 0.92A 1xzxX-4qmaA:
undetectable		 1xzxX-4qmaA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_C_DVAC8_0
(GRAMICIDIN D)		 4qma CYSTEINE DIOXYGENASE
TYPE I
(Cupriavidus
pinatubonensis) 		3 / 3 VAL A 139
TRP A  99
VAL A  98
 None
EDO  A 308 (-3.9A)
None
 0.64A 2izqC-4qmaA:
undetectable
2izqD-4qmaA:
undetectable		 2izqC-4qmaA:
9.20
2izqD-4qmaA:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 4qma CYSTEINE DIOXYGENASE
TYPE I
(Cupriavidus
pinatubonensis) 		5 / 12 LEU A 194
ALA A  56
LEU A  53
ARG A 106
LEU A  12
 None
EDO  A 313 (-3.6A)
None
None
None
 1.46A 2oaxC-4qmaA:
undetectable		 2oaxC-4qmaA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 4qma CYSTEINE DIOXYGENASE
TYPE I
(Cupriavidus
pinatubonensis) 		5 / 11 HIS A 147
HIS A  96
HIS A 162
VAL A 136
SER A 111
 FE  A 301 (-3.3A)
FE  A 301 ( 3.3A)
None
None
None
 1.30A 2zweA-4qmaA:
undetectable
2zweB-4qmaA:
undetectable		 2zweA-4qmaA:
22.22
2zweB-4qmaA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 4qma CYSTEINE DIOXYGENASE
TYPE I
(Cupriavidus
pinatubonensis) 		5 / 11 HIS A 147
HIS A  96
HIS A 162
VAL A 136
SER A 111
 FE  A 301 (-3.3A)
FE  A 301 ( 3.3A)
None
None
None
 1.26A 2zwfA-4qmaA:
undetectable
2zwfB-4qmaA:
undetectable		 2zwfA-4qmaA:
22.22
2zwfB-4qmaA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 4qma CYSTEINE DIOXYGENASE
TYPE I
(Cupriavidus
pinatubonensis) 		5 / 11 HIS A 147
HIS A  96
HIS A 162
VAL A 136
SER A 111
 FE  A 301 (-3.3A)
FE  A 301 ( 3.3A)
None
None
None
 1.25A 2zwgA-4qmaA:
undetectable
2zwgB-4qmaA:
undetectable		 2zwgA-4qmaA:
22.22
2zwgB-4qmaA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_1
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 4qma CYSTEINE DIOXYGENASE
TYPE I
(Cupriavidus
pinatubonensis) 		4 / 5 TYR A 164
HIS A 162
ASP A 145
TYR A 176
 OXY  A 302 (-4.9A)
None
None
None
 1.34A 4qdjA-4qmaA:
undetectable		 4qdjA-4qmaA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4qma CYSTEINE DIOXYGENASE
TYPE I
(Cupriavidus
pinatubonensis) 		5 / 11 GLY A 169
GLY A 188
ILE A 186
GLY A 165
PHE A  83
 None
None
None
EDO  A 308 ( 3.8A)
OXY  A 302 (-4.5A)
 1.14A 4qoiA-4qmaA:
undetectable
4qoiB-4qmaA:
undetectable		 4qoiA-4qmaA:
19.65
4qoiB-4qmaA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 4qma CYSTEINE DIOXYGENASE
TYPE I
(Cupriavidus
pinatubonensis) 		5 / 11 HIS A 147
HIS A  96
HIS A 162
VAL A 136
SER A 111
 FE  A 301 (-3.3A)
FE  A 301 ( 3.3A)
None
None
None
 1.27A 5z0hA-4qmaA:
undetectable
5z0hB-4qmaA:
undetectable		 5z0hA-4qmaA:
19.32
5z0hB-4qmaA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 4qma CYSTEINE DIOXYGENASE
TYPE I
(Cupriavidus
pinatubonensis) 		5 / 11 HIS A 147
HIS A  96
HIS A 162
VAL A 136
SER A 111
 FE  A 301 (-3.3A)
FE  A 301 ( 3.3A)
None
None
None
 1.27A 5z0iA-4qmaA:
undetectable
5z0iB-4qmaA:
undetectable		 5z0iA-4qmaA:
19.32
5z0iB-4qmaA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 4qma CYSTEINE DIOXYGENASE
TYPE I
(Cupriavidus
pinatubonensis) 		5 / 11 HIS A 147
HIS A  96
HIS A 162
VAL A 136
SER A 111
 FE  A 301 (-3.3A)
FE  A 301 ( 3.3A)
None
None
None
 1.32A 5z0jA-4qmaA:
undetectable
5z0jB-4qmaA:
undetectable		 5z0jA-4qmaA:
19.32
5z0jB-4qmaA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 4qma CYSTEINE DIOXYGENASE
TYPE I
(Cupriavidus
pinatubonensis) 		5 / 11 HIS A 147
HIS A  96
HIS A 162
VAL A 136
SER A 111
 FE  A 301 (-3.3A)
FE  A 301 ( 3.3A)
None
None
None
 1.30A 5z0kA-4qmaA:
undetectable
5z0kB-4qmaA:
undetectable		 5z0kA-4qmaA:
19.32
5z0kB-4qmaA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 4qma CYSTEINE DIOXYGENASE
TYPE I
(Cupriavidus
pinatubonensis) 		5 / 11 HIS A 147
HIS A  96
HIS A 162
VAL A 136
SER A 111
 FE  A 301 (-3.3A)
FE  A 301 ( 3.3A)
None
None
None
 1.25A 5z0lA-4qmaA:
undetectable
5z0lB-4qmaA:
undetectable		 5z0lA-4qmaA:
19.32
5z0lB-4qmaA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 4qma CYSTEINE DIOXYGENASE
TYPE I
(Cupriavidus
pinatubonensis) 		5 / 11 HIS A 147
HIS A  96
HIS A 162
VAL A 136
SER A 111
 FE  A 301 (-3.3A)
FE  A 301 ( 3.3A)
None
None
None
 1.29A 5z0mA-4qmaA:
undetectable
5z0mB-4qmaA:
undetectable		 5z0mA-4qmaA:
17.87
5z0mB-4qmaA:
19.32