SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qmf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4qmf KRR1 SMALL SUBUNIT
PROCESSOME COMPONENT
(Saccharomyces
cerevisiae) 		3 / 3 LEU D 100
HIS D  67
ILE D  93
 None
 0.66A 1s9pB-4qmfD:
undetectable		 1s9pB-4qmfD:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 4qmf KRR1 SMALL SUBUNIT
PROCESSOME COMPONENT
(Saccharomyces
cerevisiae) 		4 / 6 THR D  43
THR D  81
THR D  84
ASP D  90
 None
 1.30A 2okcB-4qmfD:
undetectable		 2okcB-4qmfD:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRM_A_VD3A502_1
(VITAMIN D(3)
25-HYDROXYLASE)		 4qmf KRR1 SMALL SUBUNIT
PROCESSOME COMPONENT
(Saccharomyces
cerevisiae) 		5 / 12 LEU D 103
MET D 174
LEU D 117
ALA D  97
ILE D  56
 None
 1.01A 3vrmA-4qmfD:
undetectable		 3vrmA-4qmfD:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_2
(CYTOCHROME P450 3A4)		 4qmf KRR1 SMALL SUBUNIT
PROCESSOME COMPONENT
(Saccharomyces
cerevisiae) 		4 / 6 ARG D 142
ARG D 144
PHE D 131
ILE D 194
 None
 1.14A 5vceA-4qmfD:
undetectable		 5vceA-4qmfD:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 4qmf KRR1 SMALL SUBUNIT
PROCESSOME COMPONENT
(Saccharomyces
cerevisiae) 		5 / 12 MET D 121
ILE D 116
ASP D 120
LEU D 100
LEU D  64
 None
 1.19A 6b54A-4qmfD:
undetectable		 6b54A-4qmfD:
22.73