SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qmh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)
4qmh LP04448P
(Drosophila
melanogaster)
3 / 3 TRP A 999
ALA A 993
VAL A1037
None
0.90A 1c4dC-4qmhA:
undetectable
1c4dD-4qmhA:
undetectable
1c4dC-4qmhA:
8.00
1c4dD-4qmhA:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)
4qmh LP04448P
(Drosophila
melanogaster)
5 / 12 GLY A 899
ASN A 937
LEU A 927
ILE A 861
LEU A 884
None
1.10A 1lhuA-4qmhA:
undetectable
1lhuA-4qmhA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)
4qmh LP04448P
(Drosophila
melanogaster)
3 / 3 ALA A 906
HIS A 907
VAL A 910
None
0.39A 1lqtB-4qmhA:
undetectable
1lqtB-4qmhA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)
4qmh LP04448P
(Drosophila
melanogaster)
3 / 3 ALA A 906
HIS A 907
VAL A 910
None
0.41A 1lquB-4qmhA:
undetectable
1lquB-4qmhA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)
4qmh LP04448P
(Drosophila
melanogaster)
4 / 7 PHE A 978
ILE A 983
PRO A1007
TRP A1001
None
0.97A 2y7kA-4qmhA:
undetectable
2y7kA-4qmhA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
4qmh LP04448P
(Drosophila
melanogaster)
5 / 12 GLY A 990
ILE A1050
LEU A1026
HIS A1029
MET A1022
None
1.07A 4ze2A-4qmhA:
undetectable
4ze2A-4qmhA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)
4qmh LP04448P
(Drosophila
melanogaster)
4 / 8 ILE A 916
GLY A 880
THR A 876
LEU A 865
None
1.03A 5hwaA-4qmhA:
undetectable
5hwaA-4qmhA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)
4qmh LP04448P
(Drosophila
melanogaster)
3 / 3 ALA A1079
ASN A1082
LEU A1083
None
0.24A 5i1oC-4qmhA:
undetectable
5i1oC-4qmhA:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)
4qmh LP04448P
(Drosophila
melanogaster)
3 / 3 ALA A1079
ASN A1082
LEU A1083
None
0.32A 5i1pA-4qmhA:
undetectable
5i1pA-4qmhA:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)
4qmh LP04448P
(Drosophila
melanogaster)
4 / 8 PHE A 977
LEU A 947
MET A 982
ILE A 983
None
0.92A 5mzjA-4qmhA:
undetectable
5mzjA-4qmhA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)
4qmh LP04448P
(Drosophila
melanogaster)
3 / 3 GLY A1047
LEU A1006
HIS A1051
None
0.61A 5u63A-4qmhA:
undetectable
5u63A-4qmhA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)
4qmh LP04448P
(Drosophila
melanogaster)
3 / 3 GLY A1047
LEU A1006
HIS A1051
None
0.66A 5u63B-4qmhA:
undetectable
5u63B-4qmhA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
4qmh LP04448P
(Drosophila
melanogaster)
4 / 7 ILE A 898
LEU A 901
ARG A 936
LEU A 942
None
0.90A 5xdqA-4qmhA:
1.9
5xdqJ-4qmhA:
undetectable
5xdqA-4qmhA:
18.04
5xdqJ-4qmhA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_1
(CYTOCHROME P450 1A1)
4qmh LP04448P
(Drosophila
melanogaster)
4 / 5 ILE A 888
SER A 889
ALA A 922
LEU A 905
None
1.06A 6dwnA-4qmhA:
undetectable
6dwnA-4qmhA:
16.24