SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qmi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)		 4qmi CYTOSKELETON-ASSOCIA
TED PROTEIN 5
(Homo
sapiens) 		5 / 12 VAL A 949
LEU A 881
PRO A 945
GLY A 943
LEU A 942
 None
 1.20A 3j6pB-4qmiA:
undetectable		 3j6pB-4qmiA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 4qmi CYTOSKELETON-ASSOCIA
TED PROTEIN 5
(Homo
sapiens) 		3 / 3 TRP A 968
TRP A 977
THR A 972
 None
 1.13A 4bboB-4qmiA:
undetectable		 4bboB-4qmiA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_D_ACTD1113_0
(BLR5658 PROTEIN)		 4qmi CYTOSKELETON-ASSOCIA
TED PROTEIN 5
(Homo
sapiens) 		4 / 4 TRP A1001
LEU A 978
LEU A1009
THR A1008
 None
 0.84A 4bboD-4qmiA:
undetectable		 4bboD-4qmiA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IOM_A_FOLA608_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 4qmi CYTOSKELETON-ASSOCIA
TED PROTEIN 5
(Homo
sapiens) 		4 / 7 PRO A 945
LEU A 994
LEU A 998
TRP A 968
 None
 1.05A 4iomA-4qmiA:
undetectable		 4iomA-4qmiA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4qmi CYTOSKELETON-ASSOCIA
TED PROTEIN 5
(Homo
sapiens) 		4 / 7 LYS A 906
LEU A 905
ASN A 941
LEU A 942
 None
 0.71A 4wg0B-4qmiA:
undetectable
4wg0C-4qmiA:
undetectable		 4wg0B-4qmiA:
5.29
4wg0C-4qmiA:
5.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4qmi CYTOSKELETON-ASSOCIA
TED PROTEIN 5
(Homo
sapiens) 		5 / 11 LEU A 901
LYS A 906
LEU A 905
ASN A 941
LEU A 942
 None
 0.87A 4wg0C-4qmiA:
undetectable
4wg0D-4qmiA:
undetectable
4wg0E-4qmiA:
undetectable		 4wg0C-4qmiA:
5.29
4wg0D-4qmiA:
5.29
4wg0E-4qmiA:
5.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_G_CHDG103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4qmi CYTOSKELETON-ASSOCIA
TED PROTEIN 5
(Homo
sapiens) 		5 / 11 LEU A 901
LYS A 906
LEU A 905
ASN A 941
LEU A 942
 None
 0.88A 4wg0E-4qmiA:
undetectable
4wg0F-4qmiA:
undetectable
4wg0G-4qmiA:
undetectable		 4wg0E-4qmiA:
5.29
4wg0F-4qmiA:
5.29
4wg0G-4qmiA:
5.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4qmi CYTOSKELETON-ASSOCIA
TED PROTEIN 5
(Homo
sapiens) 		4 / 7 ASN A 941
LEU A 942
LYS A 906
LEU A 905
 None
 0.70A 4wg0L-4qmiA:
undetectable
4wg0M-4qmiA:
undetectable		 4wg0L-4qmiA:
5.29
4wg0M-4qmiA:
5.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 4qmi CYTOSKELETON-ASSOCIA
TED PROTEIN 5
(Homo
sapiens) 		3 / 3 VAL A1069
LYS A1077
MET A1080
 None
 1.03A 5nknA-4qmiA:
undetectable		 5nknA-4qmiA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 4qmi CYTOSKELETON-ASSOCIA
TED PROTEIN 5
(Homo
sapiens) 		4 / 6 LYS A1005
LEU A1006
PHE A1045
LEU A1016
 None
 1.19A 5x19P-4qmiA:
undetectable		 5x19P-4qmiA:
18.08