SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qn9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		5 / 12 ALA A 310
GLY A 309
HIS A 321
HIS A 253
ASP A 189
 3PE  A 503 ( 4.7A)
None
3PE  A 503 (-3.8A)
ZN  A 501 ( 3.5A)
ZN  A 502 ( 2.5A)
 1.10A 1a4lD-4qn9A:
2.3		 1a4lD-4qn9A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 8 HIS A 343
GLY A 131
GLY A 345
LEU A 349
 ZN  A 502 ( 3.6A)
None
None
3PE  A 503 ( 4.6A)
 0.73A 1aegA-4qn9A:
undetectable		 1aegA-4qn9A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		5 / 8 HIS A 185
HIS A 253
HIS A 187
LEU A 349
HIS A 321
 ZN  A 501 (-3.6A)
ZN  A 501 ( 3.5A)
ZN  A 501 ( 3.4A)
3PE  A 503 ( 4.6A)
3PE  A 503 (-3.8A)
 1.49A 1azmA-4qn9A:
undetectable		 1azmA-4qn9A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		5 / 8 HIS A 185
HIS A 253
HIS A 187
LEU A 349
HIS A 343
 ZN  A 501 (-3.6A)
ZN  A 501 ( 3.5A)
ZN  A 501 ( 3.4A)
3PE  A 503 ( 4.6A)
ZN  A 502 ( 3.6A)
 1.44A 1azmA-4qn9A:
undetectable		 1azmA-4qn9A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 5 ASP A 284
HIS A 343
HIS A 185
HIS A 190
 ZN  A 502 (-2.5A)
ZN  A 502 ( 3.6A)
ZN  A 501 (-3.6A)
ZN  A 502 (-3.5A)
 1.20A 1ei6A-4qn9A:
undetectable		 1ei6A-4qn9A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		5 / 11 ILE A 306
SER A 269
PHE A 279
GLY A 283
PHE A 280
 None
 1.35A 1ho5A-4qn9A:
undetectable		 1ho5A-4qn9A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_B_EDTB1511_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 8 MET A 136
ARG A 202
TYR A 110
THR A 128
 None
 1.28A 1zlqB-4qn9A:
undetectable		 1zlqB-4qn9A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		5 / 11 ASP A 189
HIS A 190
HIS A 253
ASP A 284
HIS A 343
 ZN  A 502 ( 2.5A)
ZN  A 502 (-3.5A)
ZN  A 501 ( 3.5A)
ZN  A 502 (-2.5A)
ZN  A 502 ( 3.6A)
 0.56A 2q0jB-4qn9A:
8.9		 2q0jB-4qn9A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 6 THR A 128
GLU A 138
PHE A 144
ILE A 178
 None
 1.44A 2w98B-4qn9A:
undetectable		 2w98B-4qn9A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		3 / 3 ARG A 164
ARG A 167
PRO A 169
 None
SO4  A 508 (-2.6A)
None
 1.11A 2wljA-4qn9A:
undetectable		 2wljA-4qn9A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOY_A_HISA1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		5 / 10 GLY A 283
ALA A 282
HIS A 185
HIS A 253
HIS A 321
 None
None
ZN  A 501 (-3.6A)
ZN  A 501 ( 3.5A)
3PE  A 503 (-3.8A)
 1.02A 3boyA-4qn9A:
undetectable
3boyC-4qn9A:
undetectable		 3boyA-4qn9A:
16.71
3boyC-4qn9A:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOY_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		5 / 10 HIS A 253
HIS A 321
GLY A 283
ALA A 282
HIS A 185
 ZN  A 501 ( 3.5A)
3PE  A 503 (-3.8A)
None
None
ZN  A 501 (-3.6A)
 1.01A 3boyA-4qn9A:
undetectable
3boyB-4qn9A:
undetectable		 3boyA-4qn9A:
16.71
3boyB-4qn9A:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOY_A_HISA3001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		5 / 10 HIS A 253
HIS A 321
GLY A 283
ALA A 282
HIS A 185
 ZN  A 501 ( 3.5A)
3PE  A 503 (-3.8A)
None
None
ZN  A 501 (-3.6A)
 1.02A 3boyB-4qn9A:
undetectable
3boyC-4qn9A:
undetectable		 3boyB-4qn9A:
16.71
3boyC-4qn9A:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 5 PRO A 358
ILE A 308
PRO A 324
TYR A 311
 None
 1.15A 3d9lA-4qn9A:
undetectable
3d9lY-4qn9A:
undetectable		 3d9lA-4qn9A:
17.37
3d9lY-4qn9A:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 6 PHE A 246
PHE A 144
HIS A 241
VAL A 244
 None
 1.14A 3lb3A-4qn9A:
undetectable		 3lb3A-4qn9A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 6 PHE A 246
PHE A 144
HIS A 241
VAL A 244
 None
 1.29A 3lb3B-4qn9A:
undetectable		 3lb3B-4qn9A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		5 / 12 HIS A 185
PHE A 316
GLN A 320
HIS A 321
HIS A 343
 ZN  A 501 (-3.6A)
None
3PE  A 503 (-4.1A)
3PE  A 503 (-3.8A)
ZN  A 502 ( 3.6A)
 1.14A 3lxeA-4qn9A:
undetectable		 3lxeA-4qn9A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		5 / 12 HIS A 185
PHE A 316
GLN A 320
HIS A 321
HIS A 343
 ZN  A 501 (-3.6A)
None
3PE  A 503 (-4.1A)
3PE  A 503 (-3.8A)
ZN  A 502 ( 3.6A)
 1.13A 3lxeB-4qn9A:
undetectable		 3lxeB-4qn9A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		3 / 3 GLY A 223
TRP A 209
VAL A 227
 None
 0.67A 3n62B-4qn9A:
undetectable		 3n62B-4qn9A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		3 / 3 GLY A 223
TRP A 209
VAL A 227
 None
 0.65A 3n65B-4qn9A:
undetectable		 3n65B-4qn9A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		3 / 3 GLY A 223
TRP A 209
VAL A 227
 None
 0.67A 3n66B-4qn9A:
undetectable		 3n66B-4qn9A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		5 / 12 HIS A 343
GLY A 309
ASP A 284
ARG A 257
ALA A 154
 ZN  A 502 ( 3.6A)
None
ZN  A 502 (-2.5A)
None
3PE  A 503 (-4.7A)
 1.04A 3sugA-4qn9A:
undetectable		 3sugA-4qn9A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		5 / 8 HIS A 185
HIS A 253
HIS A 187
LEU A 349
HIS A 321
 ZN  A 501 (-3.6A)
ZN  A 501 ( 3.5A)
ZN  A 501 ( 3.4A)
3PE  A 503 ( 4.6A)
3PE  A 503 (-3.8A)
 1.49A 3w6hA-4qn9A:
undetectable		 3w6hA-4qn9A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		5 / 8 HIS A 185
HIS A 253
HIS A 187
LEU A 349
HIS A 343
 ZN  A 501 (-3.6A)
ZN  A 501 ( 3.5A)
ZN  A 501 ( 3.4A)
3PE  A 503 ( 4.6A)
ZN  A 502 ( 3.6A)
 1.43A 3w6hA-4qn9A:
undetectable		 3w6hA-4qn9A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_B_AZMB303_1
(CARBONIC ANHYDRASE 1)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		5 / 9 HIS A 185
HIS A 253
HIS A 187
LEU A 349
HIS A 321
 ZN  A 501 (-3.6A)
ZN  A 501 ( 3.5A)
ZN  A 501 ( 3.4A)
3PE  A 503 ( 4.6A)
3PE  A 503 (-3.8A)
 1.49A 3w6hB-4qn9A:
undetectable		 3w6hB-4qn9A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_B_AZMB303_1
(CARBONIC ANHYDRASE 1)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		5 / 9 HIS A 185
HIS A 253
HIS A 187
LEU A 349
HIS A 343
 ZN  A 501 (-3.6A)
ZN  A 501 ( 3.5A)
ZN  A 501 ( 3.4A)
3PE  A 503 ( 4.6A)
ZN  A 502 ( 3.6A)
 1.43A 3w6hB-4qn9A:
undetectable		 3w6hB-4qn9A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		3 / 3 ASN A 388
ASP A 302
ASN A 277
 None
 0.80A 4agaA-4qn9A:
undetectable		 4agaA-4qn9A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1D_B_X8ZB350_1
(BETA-LACTAMASE CLASS
B VIM-2)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		5 / 10 HIS A 185
HIS A 187
ASP A 189
HIS A 253
HIS A 343
 ZN  A 501 (-3.6A)
ZN  A 501 ( 3.4A)
ZN  A 502 ( 2.5A)
ZN  A 501 ( 3.5A)
ZN  A 502 ( 3.6A)
 0.77A 4c1dB-4qn9A:
4.1		 4c1dB-4qn9A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1F_A_X8ZA300_1
(BETA-LACTAMASE IMP-1)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		5 / 11 HIS A 185
HIS A 187
ASP A 189
HIS A 253
HIS A 343
 ZN  A 501 (-3.6A)
ZN  A 501 ( 3.4A)
ZN  A 502 ( 2.5A)
ZN  A 501 ( 3.5A)
ZN  A 502 ( 3.6A)
 0.81A 4c1fA-4qn9A:
7.3
4c1fB-4qn9A:
7.6		 4c1fA-4qn9A:
22.94
4c1fB-4qn9A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1H_A_X8ZA305_1
(BETA-LACTAMASE 2)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		5 / 9 HIS A 185
HIS A 187
ASP A 189
HIS A 253
HIS A 343
 ZN  A 501 (-3.6A)
ZN  A 501 ( 3.4A)
ZN  A 502 ( 2.5A)
ZN  A 501 ( 3.5A)
ZN  A 502 ( 3.6A)
 0.79A 4c1hA-4qn9A:
8.0		 4c1hA-4qn9A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EXS_B_X8ZB301_1
(BETA-LACTAMASE NDM-1)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 8 HIS A 187
ASP A 189
HIS A 253
HIS A 343
 ZN  A 501 ( 3.4A)
ZN  A 502 ( 2.5A)
ZN  A 501 ( 3.5A)
ZN  A 502 ( 3.6A)
 0.72A 4exsB-4qn9A:
7.3		 4exsB-4qn9A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 7 HIS A 253
HIS A 190
HIS A 343
ALA A 310
 ZN  A 501 ( 3.5A)
ZN  A 502 (-3.5A)
ZN  A 502 ( 3.6A)
3PE  A 503 ( 4.7A)
 0.70A 4p6sA-4qn9A:
undetectable		 4p6sA-4qn9A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 7 HIS A 343
HIS A 190
HIS A 253
ALA A 310
 ZN  A 502 ( 3.6A)
ZN  A 502 (-3.5A)
ZN  A 501 ( 3.5A)
3PE  A 503 ( 4.7A)
 0.93A 4p6sA-4qn9A:
undetectable		 4p6sA-4qn9A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_0
(PROLINE--TRNA LIGASE)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		5 / 12 VAL A 272
THR A 249
TRP A 233
PHE A 291
GLY A  60
 None
 1.37A 4q15A-4qn9A:
undetectable		 4q15A-4qn9A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_0
(PROLINE--TRNA LIGASE)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		5 / 12 VAL A 272
THR A 249
TRP A 233
PHE A 291
GLY A  60
 None
 1.34A 4q15B-4qn9A:
undetectable		 4q15B-4qn9A:
21.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QN9_A_DXCA505_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 6 TYR A 193
TRP A 218
LYS A 221
CYH A 222
 DXC  A 504 (-4.8A)
DXC  A 504 ( 3.9A)
DXC  A 504 (-4.8A)
DXC  A 504 (-3.6A)
 0.11A 4qn9A-4qn9A:
61.9
4qn9B-4qn9A:
60.5		 4qn9A-4qn9A:
100.00
4qn9B-4qn9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QN9_B_DXCB601_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 5 TYR A 188
TRP A 218
ARG A 257
THR A 258
 3PE  A 503 ( 4.9A)
DXC  A 504 ( 3.9A)
None
DXC  A 507 (-3.7A)
 0.12A 4qn9A-4qn9A:
61.9
4qn9B-4qn9A:
60.5		 4qn9A-4qn9A:
100.00
4qn9B-4qn9A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		3 / 3 GLY A 161
PRO A 162
ALA A 348
 3PE  A 503 ( 4.5A)
3PE  A 503 ( 4.7A)
None
 0.07A 4qn9B-4qn9A:
60.5		 4qn9B-4qn9A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_A_WJZA304_0
(BETA-LACTAMASE NDM-1)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 8 HIS A 187
ASP A 189
HIS A 253
HIS A 343
 ZN  A 501 ( 3.4A)
ZN  A 502 ( 2.5A)
ZN  A 501 ( 3.5A)
ZN  A 502 ( 3.6A)
 0.69A 5a5zA-4qn9A:
7.6		 5a5zA-4qn9A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYA_A_X8ZA307_1
(METALLO-BETA-LACTAMA
SE)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		6 / 11 HIS A 185
HIS A 187
ASP A 189
HIS A 190
HIS A 253
HIS A 343
 ZN  A 501 (-3.6A)
ZN  A 501 ( 3.4A)
ZN  A 502 ( 2.5A)
ZN  A 502 (-3.5A)
ZN  A 501 ( 3.5A)
ZN  A 502 ( 3.6A)
 0.35A 5ayaA-4qn9A:
8.2		 5ayaA-4qn9A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		5 / 12 PRO A 212
PHE A 210
GLY A 283
ASP A 284
LEU A 230
 None
None
None
ZN  A 502 (-2.5A)
None
 1.16A 5h5fA-4qn9A:
undetectable		 5h5fA-4qn9A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 7 HIS A 253
HIS A 190
HIS A 343
ALA A 310
 ZN  A 501 ( 3.5A)
ZN  A 502 (-3.5A)
ZN  A 502 ( 3.6A)
3PE  A 503 ( 4.7A)
 0.73A 5i3aA-4qn9A:
undetectable		 5i3aA-4qn9A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 7 HIS A 343
HIS A 190
HIS A 253
ALA A 310
 ZN  A 502 ( 3.6A)
ZN  A 502 (-3.5A)
ZN  A 501 ( 3.5A)
3PE  A 503 ( 4.7A)
 0.88A 5i3aA-4qn9A:
undetectable		 5i3aA-4qn9A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 7 HIS A 253
HIS A 190
HIS A 343
ALA A 310
 ZN  A 501 ( 3.5A)
ZN  A 502 (-3.5A)
ZN  A 502 ( 3.6A)
3PE  A 503 ( 4.7A)
 0.73A 5i3aB-4qn9A:
undetectable		 5i3aB-4qn9A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 7 HIS A 343
HIS A 190
HIS A 253
ALA A 310
 ZN  A 502 ( 3.6A)
ZN  A 502 (-3.5A)
ZN  A 501 ( 3.5A)
3PE  A 503 ( 4.7A)
 0.86A 5i3aB-4qn9A:
undetectable		 5i3aB-4qn9A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 7 HIS A 253
HIS A 190
HIS A 343
ALA A 310
 ZN  A 501 ( 3.5A)
ZN  A 502 (-3.5A)
ZN  A 502 ( 3.6A)
3PE  A 503 ( 4.7A)
 0.73A 5i3bA-4qn9A:
undetectable		 5i3bA-4qn9A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 7 HIS A 343
HIS A 190
HIS A 253
ALA A 310
 ZN  A 502 ( 3.6A)
ZN  A 502 (-3.5A)
ZN  A 501 ( 3.5A)
3PE  A 503 ( 4.7A)
 0.87A 5i3bA-4qn9A:
undetectable		 5i3bA-4qn9A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_C_FUAC1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		3 / 3 VAL A 272
HIS A 241
VAL A 238
 None
 0.63A 5jmnC-4qn9A:
undetectable		 5jmnC-4qn9A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_A_EDTA609_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 8 MET A 136
ARG A 202
TYR A 110
THR A 128
 None
 1.29A 5l8dA-4qn9A:
undetectable		 5l8dA-4qn9A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_A_EDTA609_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 8 MET A 136
ARG A 202
TYR A 110
THR A 128
 None
 1.29A 5mwuA-4qn9A:
undetectable		 5mwuA-4qn9A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 4 ASP A 284
HIS A 190
HIS A 132
HIS A 321
 ZN  A 502 (-2.5A)
ZN  A 502 (-3.5A)
None
3PE  A 503 (-3.8A)
 1.31A 5ncdD-4qn9A:
undetectable		 5ncdD-4qn9A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 8 ASP A 284
HIS A 343
HIS A 321
HIS A 185
 ZN  A 502 (-2.5A)
ZN  A 502 ( 3.6A)
3PE  A 503 (-3.8A)
ZN  A 501 (-3.6A)
 0.91A 5nekD-4qn9A:
undetectable		 5nekD-4qn9A:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		6 / 10 HIS A 185
HIS A 187
HIS A 190
HIS A 253
ASP A 284
HIS A 321
 ZN  A 501 (-3.6A)
ZN  A 501 ( 3.4A)
ZN  A 502 (-3.5A)
ZN  A 501 ( 3.5A)
ZN  A 502 (-2.5A)
3PE  A 503 (-3.8A)
 0.34A 5nzwA-4qn9A:
12.2		 5nzwA-4qn9A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		5 / 10 HIS A 253
HIS A 185
HIS A 321
ASP A 284
HIS A 343
 ZN  A 501 ( 3.5A)
ZN  A 501 (-3.6A)
3PE  A 503 (-3.8A)
ZN  A 502 (-2.5A)
ZN  A 502 ( 3.6A)
 1.02A 5nzwA-4qn9A:
12.2		 5nzwA-4qn9A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		3 / 3 GLY A 223
TRP A 209
VAL A 227
 None
 0.65A 5vuoB-4qn9A:
undetectable		 5vuoB-4qn9A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		5 / 11 HIS A 190
HIS A 132
HIS A 321
ASP A 323
PRO A 324
 ZN  A 502 (-3.5A)
None
3PE  A 503 (-3.8A)
None
None
 1.29A 5z0fA-4qn9A:
undetectable
5z0fB-4qn9A:
undetectable		 5z0fA-4qn9A:
13.05
5z0fB-4qn9A:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJ8_A_9DCA303_0
(METALLO-BETA-LACTAMA
SE TYPE 2)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 8 HIS A 187
ASP A 189
HIS A 253
HIS A 343
 ZN  A 501 ( 3.4A)
ZN  A 502 ( 2.5A)
ZN  A 501 ( 3.5A)
ZN  A 502 ( 3.6A)
 0.78A 5zj8A-4qn9A:
2.7		 5zj8A-4qn9A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DCH_A_ACTA401_0
(SCOE PROTEIN)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		4 / 5 THR A 146
HIS A 190
ASP A 284
HIS A 343
 None
ZN  A 502 (-3.5A)
ZN  A 502 (-2.5A)
ZN  A 502 ( 3.6A)
 1.36A 6dchA-4qn9A:
undetectable		 6dchA-4qn9A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		5 / 12 LEU A 215
VAL A 181
VAL A 227
PRO A 148
LEU A 191
 None
 1.40A 6eliA-4qn9A:
undetectable		 6eliA-4qn9A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		3 / 3 LEU A 215
LEU A 191
ARG A 257
 None
 0.58A 6fgcA-4qn9A:
undetectable		 6fgcA-4qn9A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA810_0
(GEPHYRIN)		 4qn9 N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D
(Homo
sapiens) 		3 / 3 LEU A 215
LEU A 191
ARG A 257
 None
 0.54A 6fgdA-4qn9A:
undetectable		 6fgdA-4qn9A:
22.56