SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qnk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 4qnk IMIDAZOLEGLYCEROL-PH
OSPHATE DEHYDRATASE
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 GLU A  77
HIS A  73
HIS A 145
 MN  A 302 (-2.8A)
MN  A 302 (-3.5A)
MN  A 302 (-3.5A)
 0.53A 1oe2A-4qnkA:
undetectable		 1oe2A-4qnkA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 4qnk IMIDAZOLEGLYCEROL-PH
OSPHATE DEHYDRATASE
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 GLU A 173
HIS A 169
HIS A  47
 MN  A 301 (-2.7A)
MN  A 301 (-3.4A)
MN  A 301 (-3.5A)
 0.49A 1oe2A-4qnkA:
undetectable		 1oe2A-4qnkA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 4qnk IMIDAZOLEGLYCEROL-PH
OSPHATE DEHYDRATASE
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 11 GLY A  84
ALA A  86
ALA A  90
LEU A  91
VAL A  60
 None
 1.10A 1ukbA-4qnkA:
undetectable		 1ukbA-4qnkA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4qnk IMIDAZOLEGLYCEROL-PH
OSPHATE DEHYDRATASE
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 ASP A  78
ASP A  71
ASP A  67
GLU A  77
 None
None
None
MN  A 302 (-2.8A)
 1.03A 4gkiE-4qnkA:
undetectable
4gkiG-4qnkA:
undetectable		 4gkiE-4qnkA:
20.56
4gkiG-4qnkA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qnk IMIDAZOLEGLYCEROL-PH
OSPHATE DEHYDRATASE
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 11 HIS A 145
SER A 149
THR A  40
THR A  75
ALA A  80
 MN  A 302 (-3.5A)
None
None
None
None
 1.45A 4qvqV-4qnkA:
undetectable
4qvqb-4qnkA:
undetectable		 4qvqV-4qnkA:
21.18
4qvqb-4qnkA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS1_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4qnk IMIDAZOLEGLYCEROL-PH
OSPHATE DEHYDRATASE
2, CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 ILE A  83
PHE A 179
THR A 187
LEU A 118
 None
 0.87A 5hs1A-4qnkA:
undetectable		 5hs1A-4qnkA:
16.86