SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qo6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DGM_A_ADNA375_1
(ADENOSINE KINASE)		 4qo6 ADENYLATE
CYCLASE-LIKE PROTEIN
(Chlamydia
trachomatis) 		5 / 9 ASN A 621
ILE A 623
ASP A 625
GLY A 594
LEU A 683
 None
 1.42A 1dgmA-4qo6A:
undetectable		 1dgmA-4qo6A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4qo6 ADENYLATE
CYCLASE-LIKE PROTEIN
(Chlamydia
trachomatis) 		4 / 8 ASP A 568
SER A 613
PHE A 614
ASP A 564
 None
 1.12A 1p7lC-4qo6A:
undetectable		 1p7lC-4qo6A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4qo6 ADENYLATE
CYCLASE-LIKE PROTEIN
(Chlamydia
trachomatis) 		4 / 8 ASP A 568
SER A 613
PHE A 614
ASP A 564
 None
 1.11A 1p7lD-4qo6A:
undetectable		 1p7lD-4qo6A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4qo6 ADENYLATE
CYCLASE-LIKE PROTEIN
(Chlamydia
trachomatis) 		4 / 8 ASP A 568
SER A 613
PHE A 614
ASP A 564
 None
 1.12A 1rg9A-4qo6A:
undetectable		 1rg9A-4qo6A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4qo6 ADENYLATE
CYCLASE-LIKE PROTEIN
(Chlamydia
trachomatis) 		4 / 8 ASP A 568
SER A 613
PHE A 614
ASP A 564
 None
 1.10A 1rg9B-4qo6A:
undetectable		 1rg9B-4qo6A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4qo6 ADENYLATE
CYCLASE-LIKE PROTEIN
(Chlamydia
trachomatis) 		4 / 8 ASP A 568
SER A 613
PHE A 614
ASP A 564
 None
 1.12A 1rg9C-4qo6A:
undetectable		 1rg9C-4qo6A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4qo6 ADENYLATE
CYCLASE-LIKE PROTEIN
(Chlamydia
trachomatis) 		4 / 8 ASP A 568
SER A 613
PHE A 614
ASP A 564
 None
 1.12A 1rg9D-4qo6A:
3.5		 1rg9D-4qo6A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDB_A_NPSA1591_1
(SERUM ALBUMIN)		 4qo6 ADENYLATE
CYCLASE-LIKE PROTEIN
(Chlamydia
trachomatis) 		4 / 8 ILE A 657
PHE A 678
LEU A 684
PHE A 655
 None
 0.90A 2vdbA-4qo6A:
undetectable		 2vdbA-4qo6A:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 4qo6 ADENYLATE
CYCLASE-LIKE PROTEIN
(Chlamydia
trachomatis) 		4 / 5 VAL A 737
LEU A 721
VAL A 710
PHE A 733
 None
 1.05A 4lb0B-4qo6A:
undetectable		 4lb0B-4qo6A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 4qo6 ADENYLATE
CYCLASE-LIKE PROTEIN
(Chlamydia
trachomatis) 		4 / 8 ASP A 568
SER A 613
PHE A 614
ASP A 564
 None
 1.16A 5t8sB-4qo6A:
undetectable		 5t8sB-4qo6A:
19.36