SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qor'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 4qor CATALASE
(Bacillus
pumilus) 		3 / 3 THR A 169
PRO A 172
THR A 171
 None
 0.88A 1a7yB-4qorA:
undetectable		 1a7yB-4qorA:
2.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 4qor CATALASE
(Bacillus
pumilus) 		5 / 12 LEU A 150
ASP A 447
HIS A 100
LEU A 108
GLY A 186
 2CH  A 503 (-4.2A)
2CH  A 503 ( 4.6A)
None
None
None
 1.43A 1d4fB-4qorA:
undetectable		 1d4fB-4qorA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 4qor CATALASE
(Bacillus
pumilus) 		3 / 3 THR A 169
PRO A 172
THR A 171
 None
 0.90A 1dscC-4qorA:
undetectable		 1dscC-4qorA:
2.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 4qor CATALASE
(Bacillus
pumilus) 		3 / 3 THR A 169
PRO A 172
THR A 171
 None
 0.84A 1i3wE-4qorA:
undetectable		 1i3wE-4qorA:
2.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 4qor CATALASE
(Bacillus
pumilus) 		3 / 3 THR A 171
THR A 169
PRO A 172
 None
 0.85A 1i3wF-4qorA:
undetectable		 1i3wF-4qorA:
2.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 4qor CATALASE
(Bacillus
pumilus) 		3 / 3 THR A 171
THR A 169
PRO A 172
 None
 0.85A 1i3wG-4qorA:
undetectable		 1i3wG-4qorA:
2.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 4qor CATALASE
(Bacillus
pumilus) 		3 / 3 THR A 171
THR A 169
PRO A 172
 None
 0.85A 1i3wH-4qorA:
undetectable		 1i3wH-4qorA:
2.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 4qor CATALASE
(Bacillus
pumilus) 		3 / 3 THR A 169
PRO A 172
THR A 171
 None
 0.82A 1mnvD-4qorA:
undetectable		 1mnvD-4qorA:
2.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 4qor CATALASE
(Bacillus
pumilus) 		3 / 3 THR A 169
PRO A 172
THR A 171
 None
 0.80A 1ovfB-4qorA:
undetectable		 1ovfB-4qorA:
2.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 4qor CATALASE
(Bacillus
pumilus) 		3 / 3 THR A 169
PRO A 172
THR A 171
 None
 0.88A 1unjL-4qorA:
undetectable		 1unjL-4qorA:
2.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 4qor CATALASE
(Bacillus
pumilus) 		3 / 3 THR A 171
THR A 169
PRO A 172
 None
 0.87A 1unjL-4qorA:
undetectable		 1unjL-4qorA:
2.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 4qor CATALASE
(Bacillus
pumilus) 		3 / 3 THR A 171
THR A 169
PRO A 172
 None
 0.86A 1unmE-4qorA:
undetectable		 1unmE-4qorA:
2.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 4qor CATALASE
(Bacillus
pumilus) 		3 / 3 THR A 169
PRO A 172
THR A 171
 None
 0.86A 1unmF-4qorA:
undetectable		 1unmF-4qorA:
2.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1503_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4qor CATALASE
(Bacillus
pumilus) 		4 / 4 LYS A 437
ARG A 473
ASP A 467
ASP A 469
 None
 1.32A 1zlqA-4qorA:
0.0		 1zlqA-4qorA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4qor CATALASE
(Bacillus
pumilus) 		5 / 12 TYR A 248
ASN A 303
ARG A  59
ASP A 246
ALA A 243
 None
 1.15A 2br4B-4qorA:
undetectable		 2br4B-4qorA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)		 4qor CATALASE
(Bacillus
pumilus) 		4 / 5 ALA A  61
GLU A 106
ALA A 243
MET A 194
 None
 1.36A 3r9tC-4qorA:
undetectable		 3r9tC-4qorA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 4qor CATALASE
(Bacillus
pumilus) 		3 / 3 ASN A 190
ALA A 192
ARG A 250
 None
 0.72A 3tj7C-4qorA:
undetectable
3tj7D-4qorA:
0.3		 3tj7C-4qorA:
16.92
3tj7D-4qorA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 4qor CATALASE
(Bacillus
pumilus) 		5 / 12 PHE A 114
GLY A 129
ALA A  63
GLY A  62
MET A 298
 None
HEM  A 501 ( 3.8A)
None
None
None
 1.01A 3v3oA-4qorA:
undetectable		 3v3oA-4qorA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)		 4qor CATALASE
(Bacillus
pumilus) 		5 / 12 PHE A 114
GLY A 129
ALA A  63
GLY A  62
MET A 298
 None
HEM  A 501 ( 3.8A)
None
None
None
 1.19A 3v3oB-4qorA:
undetectable		 3v3oB-4qorA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_0
(PUTATIVE REGULATORY
PROTEIN)		 4qor CATALASE
(Bacillus
pumilus) 		5 / 12 LEU A 127
SER A 197
TYR A 216
ILE A 325
ALA A  79
 None
 1.26A 3vw1D-4qorA:
undetectable		 3vw1D-4qorA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 4qor CATALASE
(Bacillus
pumilus) 		5 / 11 PHE A 114
GLY A 129
ALA A  63
GLY A  62
MET A 298
 None
HEM  A 501 ( 3.8A)
None
None
None
 1.31A 4a6nA-4qorA:
undetectable		 4a6nA-4qorA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 4qor CATALASE
(Bacillus
pumilus) 		4 / 6 GLY A 129
ASP A 126
PRO A 318
ARG A 336
 HEM  A 501 ( 3.8A)
None
None
HEM  A 501 ( 3.4A)
 1.07A 4lajA-4qorA:
undetectable
4lajB-4qorA:
undetectable		 4lajA-4qorA:
21.04
4lajB-4qorA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 4qor CATALASE
(Bacillus
pumilus) 		4 / 6 GLY A 198
ASP A 126
PRO A 318
ARG A 336
 None
None
None
HEM  A 501 ( 3.4A)
 0.96A 4lajA-4qorA:
undetectable
4lajB-4qorA:
undetectable		 4lajA-4qorA:
21.04
4lajB-4qorA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4qor CATALASE
(Bacillus
pumilus) 		4 / 5 ILE A  40
LEU A  39
ASP A  47
GLU A  41
 None
 0.97A 4nkxB-4qorA:
undetectable		 4nkxB-4qorA:
21.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QOP_A_HQEA503_1
(CATALASE)		 4qor CATALASE
(Bacillus
pumilus) 		9 / 9 ILE A  99
ASP A 110
PRO A 111
PHE A 136
LEU A 150
TYR A 164
LEU A 181
PHE A 182
ASP A 447
 None
2CH  A 503 (-4.1A)
None
2CH  A 503 (-4.1A)
2CH  A 503 (-4.2A)
2CH  A 503 (-4.1A)
2CH  A 503 (-4.8A)
2CH  A 503 ( 4.8A)
2CH  A 503 ( 4.6A)
 0.11A 4qopA-4qorA:
64.6		 4qopA-4qorA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QOP_B_HQEB503_1
(CATALASE)		 4qor CATALASE
(Bacillus
pumilus) 		9 / 9 ILE A  99
ASP A 110
PRO A 111
PHE A 136
LEU A 150
TYR A 164
LEU A 181
PHE A 182
ASP A 447
 None
2CH  A 503 (-4.1A)
None
2CH  A 503 (-4.1A)
2CH  A 503 (-4.2A)
2CH  A 503 (-4.1A)
2CH  A 503 (-4.8A)
2CH  A 503 ( 4.8A)
2CH  A 503 ( 4.6A)
 0.12A 4qopB-4qorA:
64.3		 4qopB-4qorA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QOP_C_HQEC503_1
(CATALASE)		 4qor CATALASE
(Bacillus
pumilus) 		8 / 8 ILE A  99
ASP A 110
PRO A 111
PHE A 136
LEU A 150
TYR A 164
LEU A 181
PHE A 182
 None
2CH  A 503 (-4.1A)
None
2CH  A 503 (-4.1A)
2CH  A 503 (-4.2A)
2CH  A 503 (-4.1A)
2CH  A 503 (-4.8A)
2CH  A 503 ( 4.8A)
 0.12A 4qopC-4qorA:
64.4		 4qopC-4qorA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QOP_D_HQED503_1
(CATALASE)		 4qor CATALASE
(Bacillus
pumilus) 		9 / 9 ILE A  99
ASP A 110
PRO A 111
LEU A 150
GLN A 159
TYR A 164
LEU A 181
PHE A 182
ASP A 447
 None
2CH  A 503 (-4.1A)
None
2CH  A 503 (-4.2A)
2CH  A 503 ( 4.5A)
2CH  A 503 (-4.1A)
2CH  A 503 (-4.8A)
2CH  A 503 ( 4.8A)
2CH  A 503 ( 4.6A)
 0.10A 4qopD-4qorA:
64.5		 4qopD-4qorA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_D_HISD302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 4qor CATALASE
(Bacillus
pumilus) 		5 / 10 SER A  83
LEU A  82
GLY A  86
THR A  89
VAL A  69
 None
 1.26A 4yb6A-4qorA:
undetectable
4yb6D-4qorA:
undetectable		 4yb6A-4qorA:
22.06
4yb6D-4qorA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4qor CATALASE
(Bacillus
pumilus) 		5 / 10 ASP A  90
VAL A  91
VAL A 116
LEU A 300
ALA A 258
 None
 1.31A 4yhaB-4qorA:
undetectable		 4yhaB-4qorA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_C_WJZC304_0
(BETA-LACTAMASE NDM-1)		 4qor CATALASE
(Bacillus
pumilus) 		4 / 7 MET A 194
HIS A  57
GLY A 129
ASN A 130
 None
HEM  A 501 ( 3.2A)
HEM  A 501 ( 3.8A)
HEM  A 502 ( 3.1A)
 1.33A 5a5zC-4qorA:
undetectable		 5a5zC-4qorA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_A_BEZA201_0
(HYDROXYNITRILE LYASE)		 4qor CATALASE
(Bacillus
pumilus) 		5 / 9 VAL A 295
PHE A  81
TYR A 125
TRP A 204
LEU A  82
 None
 1.31A 5e4dA-4qorA:
1.0		 5e4dA-4qorA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_A_ACTA601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4qor CATALASE
(Bacillus
pumilus) 		4 / 4 LYS A 437
ARG A 473
ASP A 467
ASP A 469
 None
 1.33A 5l8dA-4qorA:
0.0		 5l8dA-4qorA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_A_ACTA601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 4qor CATALASE
(Bacillus
pumilus) 		4 / 4 LYS A 437
ARG A 473
ASP A 467
ASP A 469
 None
 1.33A 5mwuA-4qorA:
0.0		 5mwuA-4qorA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_1
(REGULATORY PROTEIN
TETR)		 4qor CATALASE
(Bacillus
pumilus) 		4 / 8 GLY A 123
GLN A 344
TYR A 352
ASP A 126
 None
HEM  A 502 ( 3.7A)
None
None
 0.96A 5vlmB-4qorA:
undetectable		 5vlmB-4qorA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)		 4qor CATALASE
(Bacillus
pumilus) 		4 / 7 GLY A 123
GLN A 344
TYR A 352
ASP A 126
 None
HEM  A 502 ( 3.7A)
None
None
 0.83A 5vlmE-4qorA:
undetectable		 5vlmE-4qorA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 4qor CATALASE
(Bacillus
pumilus) 		4 / 7 GLY A 123
GLN A 344
TYR A 352
ASP A 126
 None
HEM  A 502 ( 3.7A)
None
None
 0.92A 5vlmG-4qorA:
undetectable		 5vlmG-4qorA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 4qor CATALASE
(Bacillus
pumilus) 		4 / 4 LEU A 332
ASP A 280
PRO A 281
ARG A 138
 HEM  A 502 ( 4.2A)
None
None
None
 1.14A 6fgdA-4qorA:
undetectable		 6fgdA-4qorA:
21.82