SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qpc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		 4qpc 10-FORMYLTETRAHYDROF
OLATE DEHYDROGENASE
(Danio
rerio) 		6 / 12 LEU A 278
LEU A 293
ALA A 233
ILE A 224
ILE A 211
ALA A 235
 None
 1.46A 2bxcA-4qpcA:
undetectable		 2bxcA-4qpcA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 4qpc 10-FORMYLTETRAHYDROF
OLATE DEHYDROGENASE
(Danio
rerio) 		3 / 3 GLU A 201
HIS A 125
THR A 199
 None
 0.75A 3hkuA-4qpcA:
undetectable		 3hkuA-4qpcA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4qpc 10-FORMYLTETRAHYDROF
OLATE DEHYDROGENASE
(Danio
rerio) 		5 / 12 HIS A  24
ILE A   3
VAL A  82
ILE A 103
ILE A 183
 None
 1.22A 3kpbC-4qpcA:
undetectable		 3kpbC-4qpcA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 4qpc 10-FORMYLTETRAHYDROF
OLATE DEHYDROGENASE
(Danio
rerio) 		4 / 5 VAL A 290
LEU A 280
LEU A 288
ILE A 211
 None
 0.95A 4a9jA-4qpcA:
undetectable		 4a9jA-4qpcA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4qpc 10-FORMYLTETRAHYDROF
OLATE DEHYDROGENASE
(Danio
rerio) 		5 / 12 ALA A 267
ALA A 233
ILE A 211
LEU A 288
GLY A 282
 None
 1.10A 4r38C-4qpcA:
undetectable		 4r38C-4qpcA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_B_SALB203_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 4qpc 10-FORMYLTETRAHYDROF
OLATE DEHYDROGENASE
(Danio
rerio) 		4 / 6 PRO A  84
TYR A 105
LEU A  19
VAL A   5
 None
 0.89A 5x80A-4qpcA:
undetectable
5x80B-4qpcA:
undetectable		 5x80A-4qpcA:
19.02
5x80B-4qpcA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DK1_A_GM4A301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 4qpc 10-FORMYLTETRAHYDROF
OLATE DEHYDROGENASE
(Danio
rerio) 		5 / 11 ALA A 267
TRP A 213
TYR A 306
LEU A 293
ALA A 271
 None
 1.38A 6dk1A-4qpcA:
undetectable		 6dk1A-4qpcA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DK1_B_GM4B301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 4qpc 10-FORMYLTETRAHYDROF
OLATE DEHYDROGENASE
(Danio
rerio) 		5 / 11 ALA A 267
TRP A 213
TYR A 306
LEU A 293
ALA A 271
 None
 1.33A 6dk1B-4qpcA:
undetectable		 6dk1B-4qpcA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DK1_C_GM4C301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 4qpc 10-FORMYLTETRAHYDROF
OLATE DEHYDROGENASE
(Danio
rerio) 		5 / 11 ALA A 267
TRP A 213
TYR A 306
LEU A 293
ALA A 271
 None
 1.35A 6dk1C-4qpcA:
undetectable		 6dk1C-4qpcA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_A_BEZA701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 4qpc 10-FORMYLTETRAHYDROF
OLATE DEHYDROGENASE
(Danio
rerio) 		5 / 11 LEU A 262
ALA A 271
TRP A 213
PHE A 244
ALA A 267
 None
 1.38A 6qgbA-4qpcA:
undetectable		 6qgbA-4qpcA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_E_BEZE701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 4qpc 10-FORMYLTETRAHYDROF
OLATE DEHYDROGENASE
(Danio
rerio) 		5 / 11 LEU A 262
ALA A 271
TRP A 213
PHE A 244
ALA A 267
 None
 1.37A 6qgbE-4qpcA:
undetectable		 6qgbE-4qpcA:
17.41