SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qpv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_O_CLMO221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4qpv UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 11 PHE A 309
HIS A 278
VAL A 269
PHE A 266
VAL A 166
 None
 1.42A 3u9fM-4qpvA:
undetectable
3u9fO-4qpvA:
undetectable		 3u9fM-4qpvA:
20.07
3u9fO-4qpvA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 4qpv UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 8 LEU A 247
TYR A 197
LEU A 167
TYR A 176
 None
 1.12A 3v81C-4qpvA:
undetectable		 3v81C-4qpvA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 4qpv UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 8 LEU A 247
TYR A 197
LEU A 167
TYR A 176
 None
 1.08A 4pwdC-4qpvA:
undetectable		 4pwdC-4qpvA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)		 4qpv UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 PRO A 241
LEU A 199
VAL A 113
LEU A 160
TYR A 197
 None
 1.32A 6eliA-4qpvA:
3.0		 6eliA-4qpvA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H3D_A_DHIA601_0
(DUF2338
DOMAIN-CONTAINING
PROTEIN)		 4qpv UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 5 TYR A  49
ASN A 297
TYR A 298
PHE A 248
 None
 1.41A 6h3dA-4qpvA:
undetectable		 6h3dA-4qpvA:
21.06