SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qq1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 4qq1 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 6 ALA A 452
SER A 414
TRP A 447
LEU A 519
 None
 1.13A 1gahA-4qq1A:
undetectable		 1gahA-4qq1A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 4qq1 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 7 ASN A 139
HIS A  58
PHE A  59
ILE A 134
 None
 1.42A 1tdnA-4qq1A:
undetectable		 1tdnA-4qq1A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_0
(HYPOTHETICAL PROTEIN)		 4qq1 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		5 / 12 ILE A 234
ILE A 261
GLY A 297
ALA A 263
VAL A 321
 None
 0.96A 2yvlC-4qq1A:
undetectable		 2yvlC-4qq1A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_B_VIAB901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 4qq1 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		5 / 11 LEU A 295
ALA A 324
VAL A 227
LEU A 160
PHE A 270
 None
 1.43A 3jwqB-4qq1A:
undetectable
3jwqC-4qq1A:
undetectable		 3jwqB-4qq1A:
19.78
3jwqC-4qq1A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_1
(HIV-1 PROTEASE)		 4qq1 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 7 GLY A 539
ASP A 503
VAL A 430
ILE A 344
 None
 0.75A 3t3cA-4qq1A:
undetectable		 3t3cA-4qq1A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 4qq1 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 6 GLN A 326
TYR A 167
PHE A 299
LEU A 160
 None
 1.39A 3tgvB-4qq1A:
undetectable		 3tgvB-4qq1A:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 4qq1 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 6 GLN A 326
TYR A 167
PHE A 299
LEU A 160
 None
 1.40A 3tgvD-4qq1A:
undetectable		 3tgvD-4qq1A:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4qq1 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 6 THR A 170
LEU A 198
LEU A 186
GLU A 203
 None
 1.16A 4nc3A-4qq1A:
undetectable		 4nc3A-4qq1A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_A_BRLA501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4qq1 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 5 GLY A 147
ILE A 102
LEU A 201
LEU A  70
 None
 0.80A 4o8fA-4qq1A:
undetectable		 4o8fA-4qq1A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_B_ACTB202_0
(RETINOL-BINDING
PROTEIN 2)		 4qq1 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 7 TYR A 126
LEU A 201
GLN A 110
ARG A 207
 None
 1.10A 4qzuB-4qq1A:
3.4		 4qzuB-4qq1A:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 4qq1 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 6 GLY A 153
TYR A 151
ALA A 308
ARG A 269
 None
 1.29A 4yshB-4qq1A:
undetectable		 4yshB-4qq1A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 4qq1 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		3 / 3 SER A 124
TYR A 151
TYR A 150
 None
 0.78A 5lakA-4qq1A:
undetectable
5lakI-4qq1A:
undetectable		 5lakA-4qq1A:
19.82
5lakI-4qq1A:
2.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 4qq1 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		3 / 3 SER A 124
TYR A 151
TYR A 150
 None
 0.76A 5lakC-4qq1A:
undetectable
5lakJ-4qq1A:
undetectable		 5lakC-4qq1A:
19.82
5lakJ-4qq1A:
2.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW5_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 4qq1 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 8 SER A 492
GLY A 513
GLY A 516
ALA A 518
 None
 0.71A 5vw5A-4qq1A:
undetectable		 5vw5A-4qq1A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AN0_A_HISA520_0
(HISTIDINOL
DEHYDROGENASE)		 4qq1 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 6 GLU A 179
GLU A  65
ALA A  57
LYS A  64
 None
 1.07A 6an0A-4qq1A:
undetectable		 6an0A-4qq1A:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_1
(TYROSINE-PROTEIN
KINASE ABL1)		 4qq1 TRANSFERRIN-BINDING
PROTEIN 2
(Neisseria
meningitidis) 		4 / 5 TYR A 541
VAL A 370
PHE A 570
GLY A 538
 None
 1.43A 6hd4A-4qq1A:
undetectable		 6hd4A-4qq1A:
8.94