SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qq7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4qq7 PUTATIVE STRINGENT
STARVATION PROTEIN A
(Burkholderia
cenocepacia) 		5 / 10 GLU A 109
GLY A 167
ARG A 128
ILE A 127
MET A 178
 GSH  A 301 ( 4.6A)
None
None
None
None
 1.27A 3adsA-4qq7A:
undetectable		 3adsA-4qq7A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4qq7 PUTATIVE STRINGENT
STARVATION PROTEIN A
(Burkholderia
cenocepacia) 		5 / 11 MET A  25
VAL A  19
LEU A  79
ILE A  70
TYR A  69
 None
 1.48A 3elzB-4qq7A:
undetectable		 3elzB-4qq7A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP6_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 4qq7 PUTATIVE STRINGENT
STARVATION PROTEIN A
(Burkholderia
cenocepacia) 		5 / 12 PHE A  12
CYH A  10
VAL A  32
VAL A 105
TYR A 166
 GSH  A 301 (-3.7A)
GSH  A 301 (-3.4A)
None
None
None
 1.34A 3sp6A-4qq7A:
undetectable		 3sp6A-4qq7A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 4qq7 PUTATIVE STRINGENT
STARVATION PROTEIN A
(Burkholderia
cenocepacia) 		4 / 6 PHE A  12
ARG A  15
PRO A  51
SER A  63
 GSH  A 301 (-3.7A)
None
GSH  A 301 (-4.2A)
GSH  A 301 (-2.5A)
 0.36A 3vlnA-4qq7A:
21.0		 3vlnA-4qq7A:
29.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 4qq7 PUTATIVE STRINGENT
STARVATION PROTEIN A
(Burkholderia
cenocepacia) 		4 / 6 PHE A  12
PRO A  51
GLU A  62
SER A  63
 GSH  A 301 (-3.7A)
GSH  A 301 (-4.2A)
GSH  A 301 (-3.1A)
GSH  A 301 (-2.5A)
 0.81A 3vlnA-4qq7A:
21.0		 3vlnA-4qq7A:
29.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM2_A_ACTA605_0
(SALICYLATE-AMP
LIGASE)		 4qq7 PUTATIVE STRINGENT
STARVATION PROTEIN A
(Burkholderia
cenocepacia) 		3 / 3 THR A   8
THR A 195
ARG A  17
 None
 0.76A 5wm2A-4qq7A:
undetectable		 5wm2A-4qq7A:
16.01