SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qqv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)		 4qqv INTERLEUKIN-3
RECEPTOR CLASS 2
SUBUNIT BETA
(Mus
musculus) 		3 / 3 GLU A 268
ALA A 266
SER A 263
 None
 0.59A 1errB-4qqvA:
undetectable		 1errB-4qqvA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 4qqv INTERLEUKIN-3
RECEPTOR CLASS 2
SUBUNIT BETA
(Mus
musculus) 		3 / 3 PHE A 233
SER A 243
GLN A 231
 None
 0.91A 3smtA-4qqvA:
undetectable		 3smtA-4qqvA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C66_A_H4CA1168_0
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4qqv INTERLEUKIN-3
RECEPTOR CLASS 2
SUBUNIT BETA
(Mus
musculus) 		5 / 9 PRO A 116
GLN A 114
VAL A 113
LEU A 198
LEU A 204
 None
 1.26A 4c66A-4qqvA:
undetectable		 4c66A-4qqvA:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qqv INTERLEUKIN-3
RECEPTOR CLASS 2
SUBUNIT BETA
(Mus
musculus) 		4 / 7 TRP A 164
GLU A 165
SER A 163
ARG A 195
 None
 1.28A 4k5jA-4qqvA:
undetectable
4k5jB-4qqvA:
undetectable		 4k5jA-4qqvA:
21.31
4k5jB-4qqvA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6V_E_RBFE201_1
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT B
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT E)		 4qqv INTERLEUKIN-3
RECEPTOR CLASS 2
SUBUNIT BETA
(Mus
musculus) 		4 / 5 HIS A 216
VAL A 215
GLU A 214
LYS A 158
 None
 1.32A 4p6vB-4qqvA:
undetectable
4p6vE-4qqvA:
undetectable		 4p6vB-4qqvA:
18.01
4p6vE-4qqvA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_C_URFC301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 4qqv INTERLEUKIN-3
RECEPTOR CLASS 2
SUBUNIT BETA
(Mus
musculus) 		3 / 3 ARG A 195
HIS A 171
ARG A 197
 None
 1.01A 5iaoC-4qqvA:
undetectable		 5iaoC-4qqvA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_F_URFF301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 4qqv INTERLEUKIN-3
RECEPTOR CLASS 2
SUBUNIT BETA
(Mus
musculus) 		3 / 3 ARG A 195
HIS A 171
ARG A 197
 None
 1.01A 5iaoF-4qqvA:
undetectable		 5iaoF-4qqvA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qqv INTERLEUKIN-3
RECEPTOR CLASS 2
SUBUNIT BETA
(Mus
musculus) 		4 / 7 TRP A 164
GLU A 165
SER A 163
ARG A 195
 None
 1.21A 5vv7A-4qqvA:
undetectable
5vv7B-4qqvA:
undetectable		 5vv7A-4qqvA:
21.31
5vv7B-4qqvA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qqv INTERLEUKIN-3
RECEPTOR CLASS 2
SUBUNIT BETA
(Mus
musculus) 		4 / 7 SER A 163
ARG A 195
TRP A 164
GLU A 165
 None
 1.20A 6av6A-4qqvA:
undetectable
6av6B-4qqvA:
undetectable		 6av6A-4qqvA:
13.48
6av6B-4qqvA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qqv INTERLEUKIN-3
RECEPTOR CLASS 2
SUBUNIT BETA
(Mus
musculus) 		4 / 7 TRP A 164
GLU A 165
SER A 163
ARG A 195
 None
 1.17A 6av6C-4qqvA:
undetectable
6av6D-4qqvA:
undetectable		 6av6C-4qqvA:
13.48
6av6D-4qqvA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		 4qqv INTERLEUKIN-3
RECEPTOR CLASS 2
SUBUNIT BETA
(Mus
musculus) 		4 / 5 PHE A 153
VAL A 113
PRO A 117
VAL A 194
 None
 1.37A 6ekzA-4qqvA:
undetectable		 6ekzA-4qqvA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_A_TKTA508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4qqv INTERLEUKIN-3
RECEPTOR CLASS 2
SUBUNIT BETA
(Mus
musculus) 		4 / 8 ASP A 402
ILE A 398
ASN A 371
TRP A 405
 None
 1.25A 6hisA-4qqvA:
undetectable
6hisB-4qqvA:
undetectable		 6hisA-4qqvA:
11.27
6hisB-4qqvA:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_B_TKTB508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4qqv INTERLEUKIN-3
RECEPTOR CLASS 2
SUBUNIT BETA
(Mus
musculus) 		4 / 8 ASP A 402
ILE A 398
ASN A 371
TRP A 405
 None
 1.23A 6hisB-4qqvA:
undetectable
6hisC-4qqvA:
undetectable		 6hisB-4qqvA:
11.27
6hisC-4qqvA:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_C_TKTC508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4qqv INTERLEUKIN-3
RECEPTOR CLASS 2
SUBUNIT BETA
(Mus
musculus) 		4 / 8 ASP A 402
ILE A 398
ASN A 371
TRP A 405
 None
 1.22A 6hisC-4qqvA:
undetectable
6hisD-4qqvA:
undetectable		 6hisC-4qqvA:
11.27
6hisD-4qqvA:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4qqv INTERLEUKIN-3
RECEPTOR CLASS 2
SUBUNIT BETA
(Mus
musculus) 		4 / 8 ASP A 402
ILE A 398
ASN A 371
TRP A 405
 None
 1.24A 6hisD-4qqvA:
undetectable
6hisE-4qqvA:
undetectable		 6hisD-4qqvA:
11.27
6hisE-4qqvA:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_E_TKTE501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4qqv INTERLEUKIN-3
RECEPTOR CLASS 2
SUBUNIT BETA
(Mus
musculus) 		4 / 8 ASN A 371
TRP A 405
ASP A 402
ILE A 398
 None
 1.21A 6hisA-4qqvA:
undetectable
6hisE-4qqvA:
undetectable		 6hisA-4qqvA:
11.27
6hisE-4qqvA:
11.27