SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qrj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 4qrj PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Bacteroides
uniformis) 		4 / 8 ILE A 237
PHE A 320
LEU A 282
VAL A 244
 None
 0.85A 1fslB-4qrjA:
undetectable		 1fslB-4qrjA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA734_1
(ALPHA AMYLASE)		 4qrj PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Bacteroides
uniformis) 		4 / 6 ASN A  87
HIS A 172
TYR A 133
GLY A 135
 None
 1.43A 1mxdA-4qrjA:
undetectable		 1mxdA-4qrjA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4qrj PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Bacteroides
uniformis) 		4 / 8 PRO A 163
ASP A 193
THR A 259
ASP A 219
 None
 1.13A 1p7lC-4qrjA:
undetectable		 1p7lC-4qrjA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4qrj PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Bacteroides
uniformis) 		4 / 8 PRO A 163
ASP A 193
THR A 259
ASP A 219
 None
 1.12A 1p7lD-4qrjA:
undetectable		 1p7lD-4qrjA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4qrj PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Bacteroides
uniformis) 		4 / 8 PRO A 163
ASP A 193
THR A 259
ASP A 219
 None
 1.11A 1rg9A-4qrjA:
undetectable		 1rg9A-4qrjA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4qrj PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Bacteroides
uniformis) 		4 / 8 PRO A 163
ASP A 193
THR A 259
ASP A 219
 None
 1.11A 1rg9B-4qrjA:
undetectable		 1rg9B-4qrjA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4qrj PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Bacteroides
uniformis) 		4 / 8 PRO A 163
ASP A 193
THR A 259
ASP A 219
 None
 1.12A 1rg9C-4qrjA:
undetectable		 1rg9C-4qrjA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 4qrj PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Bacteroides
uniformis) 		4 / 8 PRO A 163
ASP A 193
THR A 259
ASP A 219
 None
 1.11A 1rg9D-4qrjA:
undetectable		 1rg9D-4qrjA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 4qrj PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Bacteroides
uniformis) 		4 / 7 ASN A 319
ARG A 223
HIS A 224
VAL A 121
 None
 1.14A 1wu8A-4qrjA:
undetectable
1wu8C-4qrjA:
undetectable		 1wu8A-4qrjA:
22.91
1wu8C-4qrjA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_A_SALA1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4qrj PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Bacteroides
uniformis) 		5 / 9 THR A 137
ILE A 173
GLY A 136
TYR A 133
GLY A 115
 None
 1.43A 2y7wA-4qrjA:
undetectable		 2y7wA-4qrjA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE503_1
(PHOSPHOLIPASE A2)		 4qrj PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Bacteroides
uniformis) 		5 / 11 GLY A  35
ILE A  45
PRO A  68
PRO A  66
SER A  84
 None
None
None
PEG  A 402 (-4.1A)
PEG  A 402 (-3.5A)
 1.30A 3bjwE-4qrjA:
undetectable		 3bjwE-4qrjA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 4qrj PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Bacteroides
uniformis) 		5 / 12 GLY A  35
ILE A  45
PRO A  68
PRO A  66
SER A  84
 None
None
None
PEG  A 402 (-4.1A)
PEG  A 402 (-3.5A)
 1.23A 3bjwF-4qrjA:
undetectable		 3bjwF-4qrjA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 4qrj PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Bacteroides
uniformis) 		5 / 9 VAL A 308
GLY A 309
ILE A 293
TYR A 283
GLY A 349
 None
 1.50A 3csjB-4qrjA:
undetectable		 3csjB-4qrjA:
25.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 4qrj PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Bacteroides
uniformis) 		5 / 11 ILE A  45
ALA A  63
GLU A 104
VAL A  80
PRO A  73
 None
 0.96A 3tmzA-4qrjA:
undetectable		 3tmzA-4qrjA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4qrj PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Bacteroides
uniformis) 		4 / 6 ILE A 206
MET A 138
THR A 130
LEU A 129
 None
 1.03A 3wg7N-4qrjA:
undetectable
3wg7W-4qrjA:
undetectable		 3wg7N-4qrjA:
22.86
3wg7W-4qrjA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 4qrj PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Bacteroides
uniformis) 		4 / 7 ILE A 358
LEU A 330
ALA A  57
VAL A  58
 None
 0.75A 4g77A-4qrjA:
undetectable		 4g77A-4qrjA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_G_FOLG703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4qrj PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Bacteroides
uniformis) 		5 / 11 VAL A  83
ALA A  91
THR A  38
ARG A 318
THR A 113
 None
 1.35A 4kyaG-4qrjA:
undetectable		 4kyaG-4qrjA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 4qrj PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Bacteroides
uniformis) 		5 / 12 ASP A 357
ILE A 358
PRO A 363
HIS A 274
ASN A 321
 None
 1.25A 5k7uA-4qrjA:
undetectable		 5k7uA-4qrjA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZ0_A_ZLDA301_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ETHR)		 4qrj PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Bacteroides
uniformis) 		5 / 12 GLY A  35
ILE A  45
TYR A  37
THR A  38
LEU A  96
 None
 1.45A 5nz0A-4qrjA:
undetectable		 5nz0A-4qrjA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 4qrj PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Bacteroides
uniformis) 		4 / 8 PRO A 163
ASP A 193
THR A 259
ASP A 219
 None
 1.20A 5t8sB-4qrjA:
undetectable		 5t8sB-4qrjA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_1
(OXAC)		 4qrj PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Bacteroides
uniformis) 		4 / 5 HIS A 174
ASP A 117
ASP A  88
ARG A 167
 None
 1.48A 5w7pA-4qrjA:
undetectable		 5w7pA-4qrjA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4qrj PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Bacteroides
uniformis) 		4 / 6 ILE A 206
MET A 138
THR A 130
LEU A 129
 None
 1.03A 5z86N-4qrjA:
undetectable
5z86W-4qrjA:
undetectable		 5z86N-4qrjA:
22.86
5z86W-4qrjA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_0
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 4qrj PUTATIVE
6-PHOSPHOGLUCONOLACT
ONASE
(Bacteroides
uniformis) 		5 / 12 PRO A 317
ALA A 271
ALA A 284
ALA A 294
PHE A 296
 None
 0.92A 5zw4A-4qrjA:
undetectable		 5zw4A-4qrjA:
20.61