SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qrk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 4qrk HYPOTHETICAL PROTEIN
(Clostridium
sporogenes) 		4 / 6 LEU A 145
ILE A 235
TYR A 188
VAL A 155
 None
 1.05A 1db1A-4qrkA:
undetectable		 1db1A-4qrkA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 4qrk HYPOTHETICAL PROTEIN
(Clostridium
sporogenes) 		5 / 12 GLY A 180
GLY A 156
ILE A 235
VAL A 159
GLY A 160
 None
 0.88A 2qe6B-4qrkA:
undetectable		 2qe6B-4qrkA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_B_VD3B2001_1
(VITAMIN D
HYDROXYLASE)		 4qrk HYPOTHETICAL PROTEIN
(Clostridium
sporogenes) 		5 / 11 ILE A 122
LEU A 153
LEU A  56
ILE A 132
THR A  52
 None
 1.34A 3a50B-4qrkA:
undetectable		 3a50B-4qrkA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 4qrk HYPOTHETICAL PROTEIN
(Clostridium
sporogenes) 		4 / 6 ASN A 234
ILE A 244
ILE A 242
VAL A 206
 None
 0.98A 4olmA-4qrkA:
undetectable		 4olmA-4qrkA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 4qrk HYPOTHETICAL PROTEIN
(Clostridium
sporogenes) 		3 / 3 PHE A 141
THR A  52
LEU A 145
 None
 0.67A 4qztA-4qrkA:
undetectable		 4qztA-4qrkA:
20.96