SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qrl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q97_B_ADNB486_1 (SR PROTEIN KINASE)	4qrl	HYPOTHETICAL PROTEIN (Bacteroides uniformis)	4 / 4	VAL A 50 ALA A 61 LEU A 88 PHE A 73	None	1.06A	1q97B-4qrlA: undetectable	1q97B-4qrlA: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C8A_B_NCAB1246_0 (MONO-ADP-RIBOSYLTRAN SFERASE C3)	4qrl	HYPOTHETICAL PROTEIN (Bacteroides uniformis)	4 / 7	GLY A 75 SER A 92 PHE A 74 GLU A 91	None	0.99A	2c8aB-4qrlA: undetectable	2c8aB-4qrlA: 21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C8A_D_NCAD1247_0 (MONO-ADP-RIBOSYLTRAN SFERASE C3)	4qrl	HYPOTHETICAL PROTEIN (Bacteroides uniformis)	4 / 7	GLY A 75 SER A 92 PHE A 74 GLU A 91	None	1.02A	2c8aD-4qrlA: undetectable	2c8aD-4qrlA: 21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OU6_A_SAMA300_0 (SAM-DEPENDENT METHYLTRANSFERASE)	4qrl	HYPOTHETICAL PROTEIN (Bacteroides uniformis)	5 / 12	TYR A 118 GLY A 26 ASP A 115 LEU A 121 TRP A 32	None	1.03A	3ou6A-4qrlA: undetectable	3ou6A-4qrlA: 17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OU7_A_SAMA300_0 (SAM-DEPENDENT METHYLTRANSFERASE)	4qrl	HYPOTHETICAL PROTEIN (Bacteroides uniformis)	5 / 12	TYR A 118 GLY A 26 ASP A 115 LEU A 121 TRP A 32	None	1.00A	3ou7A-4qrlA: undetectable	3ou7A-4qrlA: 17.29

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1Q97_B_ADNB486_1","SR PROTEIN KINASE","4qrl","HYPOTHETICAL PROTEIN","Bacteroides uniformis",4,"VAL A  50;ALA A  61;LEU A  88;PHE A  73","None","1.06A","1q97B-4qrlA:undetectable","1q97B-4qrlA:16.67"],["2C8A_B_NCAB1246_0","MONO-ADP-RIBOSYLTRANSFERASE C3","4qrl","HYPOTHETICAL PROTEIN","Bacteroides uniformis",4,"GLY A  75;SER A  92;PHE A  74;GLU A  91","None","0.99A","2c8aB-4qrlA:undetectable","2c8aB-4qrlA:21.33"],["2C8A_D_NCAD1247_0","MONO-ADP-RIBOSYLTRANSFERASE C3","4qrl","HYPOTHETICAL PROTEIN","Bacteroides uniformis",4,"GLY A  75;SER A  92;PHE A  74;GLU A  91","None","1.02A","2c8aD-4qrlA:undetectable","2c8aD-4qrlA:21.33"],["3OU6_A_SAMA300_0","SAM-DEPENDENT METHYLTRANSFERASE","4qrl","HYPOTHETICAL PROTEIN","Bacteroides uniformis",5,"TYR A 118;GLY A  26;ASP A 115;LEU A 121;TRP A  32","None","1.03A","3ou6A-4qrlA:undetectable","3ou6A-4qrlA:17.29"],["3OU7_A_SAMA300_0","SAM-DEPENDENT METHYLTRANSFERASE","4qrl","HYPOTHETICAL PROTEIN","Bacteroides uniformis",5,"TYR A 118;GLY A  26;ASP A 115;LEU A 121;TRP A  32","None","1.00A","3ou7A-4qrlA:undetectable","3ou7A-4qrlA:17.29"]]