SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qsl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_1
(HIV-1 PROTEASE)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		5 / 12 GLY H 275
ALA H 274
VAL H 311
GLY H  84
ILE H 310
 None
 0.77A 1hxbA-4qslH:
undetectable		 1hxbA-4qslH:
6.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ISM_B_NCAB305_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		4 / 7 HIS H 741
LEU H 546
SER H 545
ASP H 541
 None
 1.21A 1ismB-4qslH:
undetectable		 1ismB-4qslH:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_1
(PROTEASE RETROPEPSIN)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		6 / 12 ARG H 723
ASP H 760
VAL H 759
GLY H 708
ILE H 673
ILE H 725
 None
 1.47A 1rl8A-4qslH:
undetectable		 1rl8A-4qslH:
6.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_1
(PROTEASE RETROPEPSIN)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		6 / 12 ASP H 760
VAL H 759
GLY H 708
ILE H 673
ALA H 721
ILE H 725
 None
 1.40A 1rl8A-4qslH:
undetectable		 1rl8A-4qslH:
6.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		4 / 6 SER H 770
ALA H 765
SER H 777
ASN H 803
 None
 1.17A 1yvpB-4qslH:
3.6		 1yvpB-4qslH:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_1
(HIV-1 PROTEASE)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		5 / 12 GLY H  77
ALA H  78
ASP H  79
ILE H  28
ALA H  32
 None
 0.90A 2b7zA-4qslH:
undetectable		 2b7zA-4qslH:
6.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_2
(HIV-1 PROTEASE)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		5 / 12 GLY H  77
ALA H  78
ASP H  79
ILE H  28
ALA H  32
 None
 0.88A 2b7zB-4qslH:
undetectable		 2b7zB-4qslH:
6.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		5 / 10 TYR H 287
ILE H 289
ILE H 258
GLU H 278
ILE H 212
 None
 1.35A 2dm6A-4qslH:
5.3
2dm6B-4qslH:
5.4		 2dm6A-4qslH:
13.80
2dm6B-4qslH:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_A_NCAA1501_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		4 / 7 ARG H 644
ALA H 542
ARG H 540
ASP H 763
 None
 1.09A 2e5dA-4qslH:
2.6
2e5dB-4qslH:
2.5		 2e5dA-4qslH:
19.27
2e5dB-4qslH:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		4 / 7 ARG H 644
TYR H 751
ASP H 541
GLU H 574
 None
 1.16A 2qebA-4qslH:
undetectable		 2qebA-4qslH:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_A_PRLA1188_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		4 / 8 ILE H 870
TYR H 692
ASP H 869
ARG H 684
 None
 1.10A 2v57A-4qslH:
undetectable		 2v57A-4qslH:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_C_PRLC1187_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		4 / 8 ILE H 870
TYR H 692
ASP H 869
ARG H 684
 None
 1.10A 2v57C-4qslH:
undetectable		 2v57C-4qslH:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_F_CSCF1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		3 / 3 LEU H 612
MET H 610
MET H 712
 None
 0.78A 2vavF-4qslH:
undetectable		 2vavF-4qslH:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_D_X2ND1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		5 / 12 ILE H 484
PHE H 573
ALA H 564
ALA H 562
MET H 769
 None
 1.34A 2x2nD-4qslH:
undetectable		 2x2nD-4qslH:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		5 / 12 ILE H  17
GLU H  14
HIS H 299
SER H 313
LEU H  26
 None
 1.34A 2xkwB-4qslH:
undetectable		 2xkwB-4qslH:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_D_TC9D1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		4 / 8 THR H 538
ILE H 556
ASP H 536
SER H 766
 None
 1.09A 2xytE-4qslH:
undetectable		 2xytE-4qslH:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		4 / 8 THR H 538
ILE H 556
ASP H 536
SER H 766
 None
 1.06A 2xytH-4qslH:
undetectable		 2xytH-4qslH:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		4 / 7 THR H 538
ILE H 556
ASP H 536
SER H 766
 None
 1.07A 2xytI-4qslH:
undetectable		 2xytI-4qslH:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		4 / 7 TYR H 623
VAL H 618
TYR H 620
TYR H 979
 None
 1.32A 2xz5B-4qslH:
undetectable
2xz5E-4qslH:
undetectable		 2xz5B-4qslH:
11.06
2xz5E-4qslH:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		4 / 7 TYR H 623
VAL H 618
TYR H 620
TYR H 979
 None
 1.32A 2xz5D-4qslH:
undetectable
2xz5E-4qslH:
undetectable		 2xz5D-4qslH:
11.06
2xz5E-4qslH:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		4 / 8 HIS H  43
GLY H  13
TYR H 391
ARG H  12
 None
 1.36A 3ccfA-4qslH:
4.1		 3ccfA-4qslH:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_2
(PROTEASE)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		6 / 10 ASP H 760
VAL H 759
GLY H 708
ILE H 673
ALA H 721
ILE H 725
 None
 1.40A 3ekpB-4qslH:
undetectable		 3ekpB-4qslH:
6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_2
(PROTEASE)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		6 / 9 ASP H 760
VAL H 759
GLY H 708
ILE H 673
ALA H 721
ILE H 725
 None
 1.39A 3ektB-4qslH:
undetectable		 3ektB-4qslH:
6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_2
(HIV-1 PROTEASE)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		4 / 4 GLY H 758
ASP H 760
GLY H 708
THR H 740
 None
 1.02A 3k4vC-4qslH:
undetectable		 3k4vC-4qslH:
6.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		5 / 12 ASP H1037
VAL H1041
ILE H1042
ASN H 479
ILE H1055
 None
 1.13A 3kpdB-4qslH:
undetectable		 3kpdB-4qslH:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		3 / 3 TYR H 828
GLY H 714
ASP H 711
 None
 0.71A 3ou6C-4qslH:
undetectable		 3ou6C-4qslH:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA1_A_08YA600_1
(CYTOCHROME P450 3A4)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		5 / 12 ASP H 763
ILE H 556
THR H 535
ALA H 584
ALA H 579
 None
 1.32A 3ua1A-4qslH:
undetectable		 3ua1A-4qslH:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQT_C_C5EC301_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		4 / 8 TYR H 623
VAL H 618
TYR H 620
TYR H 979
 None
 1.27A 4bqtC-4qslH:
undetectable
4bqtD-4qslH:
undetectable		 4bqtC-4qslH:
11.15
4bqtD-4qslH:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_2
(MEMBRANE LIPOPROTEIN
TPN38(B))		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		4 / 8 ASN H 273
PRO H 108
GLN H 215
ILE H 224
 None
 1.06A 4iilA-4qslH:
4.0		 4iilA-4qslH:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		4 / 8 ARG H  18
GLN H 215
GLY H 275
THR H 276
 None
 0.88A 4k87A-4qslH:
3.2		 4k87A-4qslH:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMU_H_RFPH1401_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		5 / 12 GLN H 775
ASP H 711
HIS H 739
SER H 545
LEU H 546
 None
 1.43A 4kmuH-4qslH:
undetectable		 4kmuH-4qslH:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		5 / 12 LEU H 611
GLU H 574
ASP H 763
GLY H 708
HIS H 737
 None
 1.33A 4lvcC-4qslH:
2.7		 4lvcC-4qslH:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MV7_A_PPFA501_1
(BIOTIN CARBOXYLASE)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		5 / 7 ASN H 292
ARG H 294
GLN H 296
VAL H 297
GLU H 298
 None
 0.69A 4mv7A-4qslH:
54.9		 4mv7A-4qslH:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_2
(PROTEASE)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		6 / 11 ARG H 723
ASP H 760
VAL H 759
GLY H 708
ILE H 673
ILE H 725
 None
 1.40A 4njvB-4qslH:
undetectable		 4njvB-4qslH:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_1
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		5 / 12 THR H 874
VAL H 873
THR H 580
VAL H 583
GLU H 574
 None
 1.41A 4s0vA-4qslH:
3.5		 4s0vA-4qslH:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE0_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		5 / 9 THR H 409
PHE H 405
ILE H 343
GLY H 443
LEU H 456
 None
 1.44A 4ze0A-4qslH:
undetectable		 4ze0A-4qslH:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		4 / 5 SER H 877
GLY H 578
THR H 537
GLU H 574
 None
 1.21A 5btiC-4qslH:
undetectable
5btiD-4qslH:
2.2		 5btiC-4qslH:
18.89
5btiD-4qslH:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		3 / 3 TYR H 966
TYR H 986
GLN H 987
 None
 1.13A 5jsdA-4qslH:
undetectable
5jsdB-4qslH:
1.4		 5jsdA-4qslH:
21.43
5jsdB-4qslH:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		3 / 3 TYR H 966
TYR H 986
GLN H 987
 None
 1.14A 5jsdB-4qslH:
1.5
5jsdC-4qslH:
undetectable		 5jsdB-4qslH:
21.43
5jsdC-4qslH:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_2
(TUBULIN BETA-2B
CHAIN)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		5 / 12 LEU H  88
LEU H   8
ALA H  10
ILE H  70
ALA H  73
 None
 1.17A 5nm5B-4qslH:
undetectable		 5nm5B-4qslH:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		4 / 7 VAL H 106
ILE H 104
VAL H   7
ALA H  80
 None
 0.52A 5osrA-4qslH:
0.1		 5osrA-4qslH:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		3 / 3 HIS H 741
SER H 774
ARG H 540
 None
 1.04A 5u63A-4qslH:
2.2		 5u63A-4qslH:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA402_0
(CYCLIN-G-ASSOCIATED
KINASE)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		5 / 11 SER H  89
HIS H 299
ASN H 292
ILE H 310
GLN H 314
 None
 1.33A 5y80A-4qslH:
1.3		 5y80A-4qslH:
5.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_B_LEVB801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		3 / 3 TYR H 783
LEU H 794
ASP H 536
 None
 0.49A 5zv2B-4qslH:
undetectable		 5zv2B-4qslH:
5.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		4 / 5 ASP H  38
ILE H  17
ASN H  68
TYR H  63
 None
 1.20A 6a93B-4qslH:
undetectable		 6a93B-4qslH:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		5 / 12 LEU H 611
GLU H 574
ASP H 763
GLY H 708
HIS H 737
 None
 1.38A 6aphA-4qslH:
2.5		 6aphA-4qslH:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		5 / 12 ASN H 798
PRO H 568
VAL H 606
ILE H 801
ILE H 603
 None
 1.47A 6j20A-4qslH:
undetectable		 6j20A-4qslH:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_A_LLLA301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		4 / 6 ASP H 392
GLU H  14
CYH H 399
GLU H 243
 None
 1.32A 6mn5A-4qslH:
undetectable		 6mn5A-4qslH:
5.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_C_LLLC301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		4 / 6 ASP H 392
GLU H  14
CYH H 399
GLU H 243
 None
 1.37A 6mn5C-4qslH:
undetectable		 6mn5C-4qslH:
5.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_D_LLLD301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		4 / 6 ASP H 392
GLU H  14
CYH H 399
GLU H 243
 None
 1.30A 6mn5D-4qslH:
undetectable		 6mn5D-4qslH:
5.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_E_LLLE301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4qsl PYRUVATE CARBOXYLASE
(Listeria
monocytogenes) 		4 / 7 ARG H  18
GLU H  14
ASP H 377
CYH H 399
 None
 1.09A 6mn5E-4qslH:
undetectable		 6mn5E-4qslH:
5.29