SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qt9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD6_0
(GRAMICIDIN A)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		3 / 3 TRP A 143
ALA A  75
VAL A  92
 None
 0.99A 1av2C-4qt9A:
undetectable
1av2D-4qt9A:
undetectable		 1av2C-4qt9A:
3.38
1av2D-4qt9A:
3.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		5 / 12 GLY A 451
SER A 246
MET A 443
LEU A 299
LEU A 214
 None
 1.35A 1fm6D-4qt9A:
undetectable		 1fm6D-4qt9A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		5 / 12 THR A 379
TYR A 382
ILE A 328
GLU A 273
ALA A 286
 None
 1.26A 1jtxA-4qt9A:
undetectable		 1jtxA-4qt9A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		5 / 12 ASP A 147
GLY A 146
ALA A  68
PHE A 129
LEU A 130
 None
 1.27A 1nw3A-4qt9A:
undetectable		 1nw3A-4qt9A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_1
(HISTONE
METHYLTRANSFERASE
DOT1L)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		4 / 4 THR A 370
GLN A 293
GLU A 235
ASP A 162
 None
None
ACT  A 502 ( 2.9A)
None
 1.45A 1nw3A-4qt9A:
undetectable		 1nw3A-4qt9A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		3 / 3 GLU A 285
THR A 284
LEU A 319
 None
 0.70A 1v8bC-4qt9A:
undetectable		 1v8bC-4qt9A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		3 / 3 ALA A  75
VAL A  92
TRP A 143
 None
 0.95A 2izqA-4qt9A:
undetectable
2izqB-4qt9A:
undetectable		 2izqA-4qt9A:
3.38
2izqB-4qt9A:
3.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A600_1
(ORF12)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		5 / 11 SER A  98
TYR A  63
ALA A  68
GLY A  73
SER A  72
 None
 1.33A 2xf3A-4qt9A:
undetectable		 2xf3A-4qt9A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_B_J01B600_1
(ORF12)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		5 / 11 SER A  98
TYR A  63
ALA A  68
GLY A  73
SER A  72
 None
 1.33A 2xf3B-4qt9A:
undetectable		 2xf3B-4qt9A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A600_1
(ORF12)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		5 / 10 SER A  98
TYR A  63
ALA A  68
GLY A  73
SER A  72
 None
 1.37A 2xfsA-4qt9A:
0.6		 2xfsA-4qt9A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_B_J01B600_1
(ORF12)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		5 / 11 SER A  98
TYR A  63
ALA A  68
GLY A  73
SER A  72
 None
 1.38A 2xfsB-4qt9A:
undetectable		 2xfsB-4qt9A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		5 / 12 PHE A 168
GLU A 165
ALA A 346
PHE A 290
TYR A 294
 None
ACT  A 501 (-4.1A)
None
ACT  A 501 ( 4.9A)
None
 1.27A 3apwB-4qt9A:
undetectable		 3apwB-4qt9A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		4 / 4 LEU A 455
ARG A 207
LEU A 214
ALA A 254
 None
 1.15A 3b9mA-4qt9A:
1.3		 3b9mA-4qt9A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		4 / 7 LEU A 106
ARG A 116
SER A 444
GLY A 183
 None
 1.08A 3hcrB-4qt9A:
undetectable		 3hcrB-4qt9A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		3 / 3 TRP A 143
ALA A  75
VAL A  92
 None
 0.92A 3l8lA-4qt9A:
undetectable
3l8lB-4qt9A:
undetectable		 3l8lA-4qt9A:
3.38
3l8lB-4qt9A:
3.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LMY_B_CP6B563_1
(BETA-HEXOSAMINIDASE
SUBUNIT BETA)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		5 / 12 ASP A 158
ASP A 162
GLU A 165
TRP A 216
GLU A  77
 None
None
ACT  A 501 (-4.1A)
None
None
 1.42A 3lmyB-4qt9A:
undetectable		 3lmyB-4qt9A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_A_GLYA510_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		4 / 6 GLU A 285
GLU A 273
ALA A 286
ASN A 359
 None
 1.08A 3pgyA-4qt9A:
undetectable
3pgyB-4qt9A:
undetectable		 3pgyA-4qt9A:
19.48
3pgyB-4qt9A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		4 / 8 LEU A 299
PHE A 457
TYR A 312
TYR A 233
 None
 1.30A 3po7A-4qt9A:
undetectable		 3po7A-4qt9A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		4 / 4 PHE A 290
TYR A 281
ILE A 376
LEU A 373
 ACT  A 501 ( 4.9A)
None
None
None
 1.37A 3sudA-4qt9A:
undetectable		 3sudA-4qt9A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		4 / 5 PHE A 290
TYR A 281
ILE A 376
LEU A 373
 ACT  A 501 ( 4.9A)
None
None
None
 1.28A 3sueC-4qt9A:
undetectable		 3sueC-4qt9A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UPR_A_1KXA277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		5 / 10 TYR A 179
TYR A 180
ILE A 190
VAL A 176
ILE A 126
 None
 1.44A 3uprA-4qt9A:
undetectable		 3uprA-4qt9A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		5 / 12 SER A 408
GLY A 352
ASP A 351
GLY A 365
ASP A 411
 None
 1.03A 4pevB-4qt9A:
undetectable		 4pevB-4qt9A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		4 / 8 GLY A 146
SER A  72
PHE A 129
ASN A  71
 None
 0.98A 4wryA-4qt9A:
undetectable		 4wryA-4qt9A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		4 / 8 GLY A 146
SER A  72
PHE A 129
ASN A  71
 None
 1.01A 4wrzA-4qt9A:
undetectable		 4wrzA-4qt9A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		4 / 7 GLY A 146
SER A  72
PHE A 129
ASN A  71
 None
 0.99A 4ws0A-4qt9A:
undetectable		 4ws0A-4qt9A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		4 / 8 GLY A 146
SER A  72
PHE A 129
ASN A  71
 None
 0.99A 4ws1A-4qt9A:
undetectable		 4ws1A-4qt9A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		5 / 9 ALA A 175
LEU A 297
GLY A 298
LEU A 438
LEU A 106
 None
 0.99A 5dqfA-4qt9A:
undetectable		 5dqfA-4qt9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ENT_C_MIYC901_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		5 / 9 GLN A 171
PHE A 168
GLY A  96
SER A  98
ILE A 421
 None
None
None
None
ACT  A 501 ( 4.7A)
 1.35A 5entC-4qt9A:
undetectable		 5entC-4qt9A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U98_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 4qt9 PUTATIVE
GLUCOAMYLASE
(Bacteroides
caccae) 		5 / 10 TYR A 179
TYR A 180
ILE A 190
VAL A 176
ILE A 126
 None
 1.46A 5u98A-4qt9A:
undetectable		 5u98A-4qt9A:
21.02