SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qtk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 4qtk WHITE-OPAQUE
REGULATOR 1
(Candida
albicans) 		4 / 5 HIS A 255
LEU A  32
SER A 259
LEU A 262
 None
 1.11A 1a4lB-4qtkA:
undetectable		 1a4lB-4qtkA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 4qtk WHITE-OPAQUE
REGULATOR 1
(Candida
albicans) 		5 / 11 ILE A  14
LEU A 231
ILE A  24
PRO A 248
LEU A 253
 None
 1.19A 3a51A-4qtkA:
undetectable		 3a51A-4qtkA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1N_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4qtk WHITE-OPAQUE
REGULATOR 1
(Candida
albicans) 		5 / 11 ILE A 258
ALA A  20
LEU A 211
LEU A 218
THR A  17
 None
 1.37A 4i1nA-4qtkA:
undetectable		 4i1nA-4qtkA:
18.25