SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qtq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA8_0
(GRAMICIDIN A)		 4qtq XAC2610 PROTEIN
(Xanthomonas
citri) 		4 / 4 GLY A 168
VAL A 198
TRP A 163
GLY A 165
 None
 1.35A 1ng8A-4qtqA:
undetectable		 1ng8A-4qtqA:
6.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB8_0
(GRAMICIDIN A)		 4qtq XAC2610 PROTEIN
(Xanthomonas
citri) 		4 / 4 GLY A 168
VAL A 198
TRP A 163
GLY A 165
 None
 1.35A 1ng8B-4qtqA:
undetectable		 1ng8B-4qtqA:
6.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_1
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 4qtq XAC2610 PROTEIN
(Xanthomonas
citri) 		4 / 4 SER A 192
SER A 194
LEU A 179
PHE A 189
 None
 1.25A 1r5lA-4qtqA:
undetectable		 1r5lA-4qtqA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAU_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 4qtq XAC2610 PROTEIN
(Xanthomonas
citri) 		5 / 12 ILE A  97
LEU A 123
ALA A 122
ILE A  74
LEU A  68
 None
 1.13A 3dauA-4qtqA:
undetectable		 3dauA-4qtqA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_C_VIBC223_1
(THIAMINE
PYROPHOSPHOKINASE)		 4qtq XAC2610 PROTEIN
(Xanthomonas
citri) 		4 / 8 TYR A 227
LEU A 229
LEU A 193
SER A 213
 None
 1.03A 3lm8A-4qtqA:
undetectable
3lm8C-4qtqA:
undetectable		 3lm8A-4qtqA:
21.81
3lm8C-4qtqA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 4qtq XAC2610 PROTEIN
(Xanthomonas
citri) 		5 / 12 SER A 192
VAL A 177
ILE A 152
ASP A 151
ASP A 159
 None
None
None
CA  A 301 (-3.2A)
CA  A 301 (-2.3A)
 1.49A 6bxnA-4qtqA:
undetectable		 6bxnA-4qtqA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 4qtq XAC2610 PROTEIN
(Xanthomonas
citri) 		5 / 12 ASP A 137
LEU A 179
ASP A 155
LEU A 193
LEU A 203
 None
None
CA  A 301 (-2.9A)
None
None
 1.17A 6ew0F-4qtqA:
undetectable		 6ew0F-4qtqA:
17.26