SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qtt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1AV2_C_DVAC6_0 (GRAMICIDIN A)	4qtt	MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112 (Saccharomyces cerevisiae)	3 / 3	ALA A 64 VAL A 59 TRP A 56	None	0.80A	1av2C-4qttA: undetectable 1av2D-4qttA: undetectable	1av2C-4qttA: 5.83 1av2D-4qttA: 5.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1W5U_C_DVAC6_0 (GRAMICIDIN D)	4qtt	MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112 (Saccharomyces cerevisiae)	3 / 3	ALA A 64 VAL A 59 TRP A 56	None	0.77A	1w5uC-4qttA: undetectable 1w5uD-4qttA: undetectable	1w5uC-4qttA: 5.83 1w5uD-4qttA: 5.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IZQ_B_DVAB6_0 (GRAMICIDIN D)	4qtt	MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112 (Saccharomyces cerevisiae)	3 / 3	TRP A 56 ALA A 64 VAL A 59	None	0.84A	2izqA-4qttA: undetectable 2izqB-4qttA: undetectable	2izqA-4qttA: 5.83 2izqB-4qttA: 5.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L8L_A_DVAA6_0 (GRAMICIDIN D)	4qtt	MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112 (Saccharomyces cerevisiae)	3 / 3	ALA A 64 VAL A 59 TRP A 56	None	0.81A	3l8lA-4qttA: undetectable 3l8lB-4qttA: undetectable	3l8lA-4qttA: 5.83 3l8lB-4qttA: 6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L8L_C_DVAC6_0 (GRAMICIDIN D)	4qtt	MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112 (Saccharomyces cerevisiae)	3 / 3	ALA A 64 VAL A 59 TRP A 56	None	0.82A	3l8lC-4qttA: undetectable 3l8lD-4qttA: undetectable	3l8lC-4qttA: 5.83 3l8lD-4qttA: 6.67

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1AV2_C_DVAC6_0","GRAMICIDIN A","4qtt","MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112","Saccharomyces cerevisiae",3,"ALA A  64;VAL A  59;TRP A  56","None","0.80A","1av2C-4qttA:undetectable;1av2D-4qttA:undetectable","1av2C-4qttA:5.83;1av2D-4qttA:5.83"],["1W5U_C_DVAC6_0","GRAMICIDIN D","4qtt","MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112","Saccharomyces cerevisiae",3,"ALA A  64;VAL A  59;TRP A  56","None","0.77A","1w5uC-4qttA:undetectable;1w5uD-4qttA:undetectable","1w5uC-4qttA:5.83;1w5uD-4qttA:5.83"],["2IZQ_B_DVAB6_0","GRAMICIDIN D","4qtt","MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112","Saccharomyces cerevisiae",3,"TRP A  56;ALA A  64;VAL A  59","None","0.84A","2izqA-4qttA:undetectable;2izqB-4qttA:undetectable","2izqA-4qttA:5.83;2izqB-4qttA:5.83"],["3L8L_A_DVAA6_0","GRAMICIDIN D","4qtt","MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112","Saccharomyces cerevisiae",3,"ALA A  64;VAL A  59;TRP A  56","None","0.81A","3l8lA-4qttA:undetectable;3l8lB-4qttA:undetectable","3l8lA-4qttA:5.83;3l8lB-4qttA:6.67"],["3L8L_C_DVAC6_0","GRAMICIDIN D","4qtt","MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112","Saccharomyces cerevisiae",3,"ALA A  64;VAL A  59;TRP A  56","None","0.82A","3l8lC-4qttA:undetectable;3l8lD-4qttA:undetectable","3l8lC-4qttA:5.83;3l8lD-4qttA:6.67"]]