SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4quf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MI4_A_SPMA201_1 (SPERMIDINE N1-ACETYLTRANSFERASE)	4quf	RE36324P (Drosophila melanogaster)	4 / 6	ASN A 63 TYR A 24 GLU A 23 GLU A 22	None	1.28A	4mi4A-4qufA: undetectable	4mi4A-4qufA: 13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MI4_C_SPMC201_1 (SPERMIDINE N1-ACETYLTRANSFERASE)	4quf	RE36324P (Drosophila melanogaster)	4 / 7	ASN A 63 TYR A 24 GLU A 23 GLU A 22	None	1.28A	4mi4A-4qufA: undetectable 4mi4C-4qufA: undetectable	4mi4A-4qufA: 13.04 4mi4C-4qufA: 13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MJ8_C_SPMC201_1 (SPERMIDINE N1-ACETYLTRANSFERASE)	4quf	RE36324P (Drosophila melanogaster)	4 / 7	ASN A 63 TYR A 24 GLU A 23 GLU A 22	None	1.27A	4mj8C-4qufA: undetectable	4mj8C-4qufA: 14.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4X3U_B_SVRB101_1 (CHROMOBOX PROTEIN HOMOLOG 7)	4quf	RE36324P (Drosophila melanogaster)	5 / 9	ARG A 33 LEU A 42 TRP A 45 THR A 54 TRP A 55	None	0.23A	4x3uA-4qufA: 8.6	4x3uA-4qufA: 38.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4X3U_B_SVRB101_2 (CHROMOBOX PROTEIN HOMOLOG 7)	4quf	RE36324P (Drosophila melanogaster)	5 / 10	ARG A 33 LEU A 42 TRP A 45 THR A 54 TRP A 55	None	0.25A	4x3uB-4qufA: 9.1	4x3uB-4qufA: 38.81

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4MI4_A_SPMA201_1","SPERMIDINE N1-ACETYLTRANSFERASE","4quf","RE36324P","Drosophila melanogaster",4,"ASN A  63;TYR A  24;GLU A  23;GLU A  22","None","1.28A","4mi4A-4qufA:undetectable","4mi4A-4qufA:13.04"],["4MI4_C_SPMC201_1","SPERMIDINE N1-ACETYLTRANSFERASE;SPERMIDINE N1-ACETYLTRANSFERASE","4quf","RE36324P","Drosophila melanogaster",4,"ASN A  63;TYR A  24;GLU A  23;GLU A  22","None","1.28A","4mi4A-4qufA:undetectable;4mi4C-4qufA:undetectable","4mi4A-4qufA:13.04;4mi4C-4qufA:13.04"],["4MJ8_C_SPMC201_1","SPERMIDINE N1-ACETYLTRANSFERASE","4quf","RE36324P","Drosophila melanogaster",4,"ASN A  63;TYR A  24;GLU A  23;GLU A  22","None","1.27A","4mj8C-4qufA:undetectable","4mj8C-4qufA:14.72"],["4X3U_B_SVRB101_1","CHROMOBOX PROTEIN HOMOLOG 7;CHROMOBOX PROTEIN HOMOLOG 7","4quf","RE36324P","Drosophila melanogaster",5,"ARG A  33;LEU A  42;TRP A  45;THR A  54;TRP A  55","None","0.23A","4x3uA-4qufA:8.6","4x3uA-4qufA:38.81"],["4X3U_B_SVRB101_2","CHROMOBOX PROTEIN HOMOLOG 7","4quf","RE36324P","Drosophila melanogaster",5,"ARG A  33;LEU A  42;TRP A  45;THR A  54;TRP A  55","None","0.25A","4x3uB-4qufA:9.1","4x3uB-4qufA:38.81"]]