SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qus'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_B_NOVB2300_1
(TOPOISOMERASE IV
SUBUNIT B)		 4qus ACETYLTRANSFERASE
YPEA
(Escherichia
coli) 		5 / 12 ASP A  53
GLU A  49
ARG A   4
ALA A  86
ILE A  83
 None
 1.38A 1s14B-4qusA:
undetectable		 1s14B-4qusA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		 4qus ACETYLTRANSFERASE
YPEA
(Escherichia
coli) 		5 / 12 ILE A 105
LEU A  44
VAL A  58
GLU A  92
LEU A  91
 None
 1.34A 2bxfB-4qusA:
undetectable		 2bxfB-4qusA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 4qus ACETYLTRANSFERASE
YPEA
(Escherichia
coli) 		4 / 5 THR A  16
ILE A  15
GLU A  31
PHE A   6
 None
 1.28A 4ac9C-4qusA:
undetectable		 4ac9C-4qusA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4qus ACETYLTRANSFERASE
YPEA
(Escherichia
coli) 		4 / 5 THR A  16
ILE A  15
GLU A  31
PHE A   6
 None
 1.34A 4acaC-4qusA:
undetectable		 4acaC-4qusA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4qus ACETYLTRANSFERASE
YPEA
(Escherichia
coli) 		4 / 5 THR A  16
ILE A  15
GLU A  31
PHE A   6
 None
 1.26A 4acbC-4qusA:
undetectable		 4acbC-4qusA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4qus ACETYLTRANSFERASE
YPEA
(Escherichia
coli) 		4 / 8 LEU A  24
PRO A  76
VAL A  54
GLY A  56
 None
 0.98A 4klrB-4qusA:
undetectable		 4klrB-4qusA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 4qus ACETYLTRANSFERASE
YPEA
(Escherichia
coli) 		5 / 12 GLY A  60
ALA A  69
TYR A 123
ASN A  89
GLU A  92
 None
 1.24A 4pb1A-4qusA:
undetectable		 4pb1A-4qusA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 4qus ACETYLTRANSFERASE
YPEA
(Escherichia
coli) 		5 / 12 GLY A  60
TYR A 123
LEU A  72
ASN A  89
GLU A  92
 None
 1.23A 4pb1A-4qusA:
undetectable		 4pb1A-4qusA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 4qus ACETYLTRANSFERASE
YPEA
(Escherichia
coli) 		5 / 12 GLY A  60
ALA A  69
TYR A 123
ASN A  89
GLU A  92
 None
 1.23A 4pd5A-4qusA:
undetectable		 4pd5A-4qusA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 4qus ACETYLTRANSFERASE
YPEA
(Escherichia
coli) 		5 / 12 GLY A  60
TYR A 123
LEU A  72
ASN A  89
GLU A  92
 None
 1.24A 4pd5A-4qusA:
undetectable		 4pd5A-4qusA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H4D_A_BBIA403_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 4qus ACETYLTRANSFERASE
YPEA
(Escherichia
coli) 		4 / 6 ARG A   4
GLU A   2
GLU A  13
VAL A  55
 None
 1.33A 5h4dA-4qusA:
undetectable		 5h4dA-4qusA:
18.82