SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qv9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR K   1
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.63A 2f162-4qv9K:
28.9		 2f162-4qv9K:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   2
THR K   1
SER K 174
GLY K 173
ALA K 165
 None
 0.99A 2f162-4qv9K:
28.9		 2f162-4qv9K:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR K   1
ALA K  27
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.49A 2f16H-4qv9K:
29.1
2f16I-4qv9K:
21.2		 2f16H-4qv9K:
29.57
2f16I-4qv9K:
27.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 10 ALA K  20
ALA K  22
ALA K  27
VAL K  31
GLY K  48
 None
 0.63A 2f16K-4qv9K:
38.2
2f16L-4qv9K:
23.4		 2f16K-4qv9K:
99.53
2f16L-4qv9K:
21.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		9 / 10 THR K   1
ALA K  20
THR K  21
ALA K  22
ALA K  27
VAL K  31
LYS K  33
GLY K  47
ALA K  49
 None
 0.48A 2f16K-4qv9K:
38.2
2f16L-4qv9K:
23.4		 2f16K-4qv9K:
99.53
2f16L-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR K   1
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.62A 2f16N-4qv9K:
28.9		 2f16N-4qv9K:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   2
THR K   1
SER K 174
GLY K 173
ALA K 165
 None
 0.98A 2f16N-4qv9K:
28.9		 2f16N-4qv9K:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR K   1
ALA K  27
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.50A 2f16V-4qv9K:
29.1
2f16W-4qv9K:
25.6		 2f16V-4qv9K:
29.57
2f16W-4qv9K:
27.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 10 ALA K  20
ALA K  22
ALA K  27
VAL K  31
GLY K  48
 None
 0.62A 2f16Y-4qv9K:
38.2
2f16Z-4qv9K:
23.2		 2f16Y-4qv9K:
99.53
2f16Z-4qv9K:
21.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		9 / 10 THR K   1
ALA K  20
THR K  21
ALA K  22
ALA K  27
VAL K  31
LYS K  33
GLY K  47
ALA K  49
 None
 0.48A 2f16Y-4qv9K:
38.2
2f16Z-4qv9K:
23.2		 2f16Y-4qv9K:
99.53
2f16Z-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 12 THR K   1
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.62A 3mg02-4qv9K:
28.8
3mg0V-4qv9K:
29.2		 3mg02-4qv9K:
27.18
3mg0V-4qv9K:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR K   2
THR K   1
SER K 174
GLY K 173
ALA K 165
 None
 0.95A 3mg02-4qv9K:
28.8
3mg0V-4qv9K:
29.2		 3mg02-4qv9K:
27.18
3mg0V-4qv9K:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR K   1
THR K  21
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.50A 3mg0H-4qv9K:
29.2
3mg0I-4qv9K:
25.6		 3mg0H-4qv9K:
29.57
3mg0I-4qv9K:
27.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		10 / 11 THR K   1
ALA K  20
THR K  21
ALA K  27
VAL K  31
LYS K  33
ALA K  46
GLY K  47
ALA K  49
SER K 131
 None
 0.52A 3mg0K-4qv9K:
38.3
3mg0L-4qv9K:
23.5		 3mg0K-4qv9K:
99.53
3mg0L-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR K   1
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.62A 3mg0N-4qv9K:
28.8		 3mg0N-4qv9K:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   2
THR K   1
SER K 174
GLY K 173
ALA K 165
 None
 0.92A 3mg0N-4qv9K:
28.8		 3mg0N-4qv9K:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR K   1
ALA K  27
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.57A 3mg0V-4qv9K:
29.2
3mg0W-4qv9K:
25.6		 3mg0V-4qv9K:
29.57
3mg0W-4qv9K:
27.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 ALA K  20
ALA K  22
ALA K  27
VAL K  31
GLY K  48
 None
 0.65A 3mg0Y-4qv9K:
23.3
3mg0Z-4qv9K:
23.1		 3mg0Y-4qv9K:
99.53
3mg0Z-4qv9K:
21.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		11 / 12 THR K   1
ALA K  20
THR K  21
ALA K  22
ALA K  27
VAL K  31
LYS K  33
ALA K  46
GLY K  47
ALA K  49
SER K 131
 None
 0.50A 3mg0Y-4qv9K:
23.3
3mg0Z-4qv9K:
23.1		 3mg0Y-4qv9K:
99.53
3mg0Z-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.50A 4qvlV-4qv9K:
29.2
4qvlb-4qv9K:
28.9		 4qvlV-4qv9K:
29.29
4qvlb-4qv9K:
27.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
 None
 0.83A 4qvlK-4qv9K:
39.1
4qvlL-4qv9K:
23.6		 4qvlK-4qv9K:
99.53
4qvlL-4qv9K:
21.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 11 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.51A 4qvlK-4qv9K:
39.1
4qvlL-4qv9K:
23.6		 4qvlK-4qv9K:
99.53
4qvlL-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.50A 4qvlH-4qv9K:
27.5
4qvlN-4qv9K:
28.9		 4qvlH-4qv9K:
29.29
4qvlN-4qv9K:
27.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
 None
 0.82A 4qvlY-4qv9K:
39.1
4qvlZ-4qv9K:
23.4		 4qvlY-4qv9K:
99.53
4qvlZ-4qv9K:
21.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 11 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.51A 4qvlY-4qv9K:
39.1
4qvlZ-4qv9K:
23.4		 4qvlY-4qv9K:
99.53
4qvlZ-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.51A 4qvmV-4qv9K:
29.2
4qvmb-4qv9K:
28.8		 4qvmV-4qv9K:
29.29
4qvmb-4qv9K:
27.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 9 ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
 None
 0.80A 4qvmK-4qv9K:
38.6
4qvmL-4qv9K:
23.5		 4qvmK-4qv9K:
99.06
4qvmL-4qv9K:
21.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 9 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.52A 4qvmK-4qv9K:
38.6
4qvmL-4qv9K:
23.5		 4qvmK-4qv9K:
99.06
4qvmL-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.52A 4qvmH-4qv9K:
27.5
4qvmN-4qv9K:
28.8		 4qvmH-4qv9K:
29.29
4qvmN-4qv9K:
27.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 10 ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
 None
 0.79A 4qvmY-4qv9K:
38.5
4qvmZ-4qv9K:
23.2		 4qvmY-4qv9K:
99.06
4qvmZ-4qv9K:
21.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 10 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.52A 4qvmY-4qv9K:
38.5
4qvmZ-4qv9K:
23.2		 4qvmY-4qv9K:
99.06
4qvmZ-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 12 THR K   1
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.58A 4qvnV-4qv9K:
29.2
4qvnb-4qv9K:
28.9		 4qvnV-4qv9K:
29.29
4qvnb-4qv9K:
27.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 9 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.52A 4qvnK-4qv9K:
38.7
4qvnL-4qv9K:
23.5		 4qvnK-4qv9K:
99.06
4qvnL-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 12 THR K   1
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.58A 4qvnH-4qv9K:
27.4
4qvnN-4qv9K:
28.9		 4qvnH-4qv9K:
29.29
4qvnN-4qv9K:
27.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 9 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.50A 4qvnY-4qv9K:
38.7
4qvnZ-4qv9K:
23.3		 4qvnY-4qv9K:
99.06
4qvnZ-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.51A 4qvpV-4qv9K:
29.2
4qvpb-4qv9K:
28.9		 4qvpV-4qv9K:
29.29
4qvpb-4qv9K:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.36A 4qvpH-4qv9K:
27.5
4qvpI-4qv9K:
25.6		 4qvpH-4qv9K:
29.29
4qvpI-4qv9K:
27.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 10 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.54A 4qvpK-4qv9K:
38.7
4qvpL-4qv9K:
23.2		 4qvpK-4qv9K:
99.06
4qvpL-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.50A 4qvpH-4qv9K:
27.5
4qvpN-4qv9K:
28.9		 4qvpH-4qv9K:
29.29
4qvpN-4qv9K:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.35A 4qvpV-4qv9K:
29.2
4qvpW-4qv9K:
25.6		 4qvpV-4qv9K:
29.29
4qvpW-4qv9K:
27.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 10 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.54A 4qvpY-4qv9K:
38.7
4qvpZ-4qv9K:
23.3		 4qvpY-4qv9K:
99.06
4qvpZ-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.54A 4qvqV-4qv9K:
29.2
4qvqb-4qv9K:
28.8		 4qvqV-4qv9K:
29.29
4qvqb-4qv9K:
27.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 9 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.52A 4qvqK-4qv9K:
38.3
4qvqL-4qv9K:
23.5		 4qvqK-4qv9K:
99.06
4qvqL-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.53A 4qvqH-4qv9K:
27.4
4qvqN-4qv9K:
28.8		 4qvqH-4qv9K:
29.29
4qvqN-4qv9K:
27.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 9 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.50A 4qvqY-4qv9K:
38.3
4qvqZ-4qv9K:
23.2		 4qvqY-4qv9K:
99.06
4qvqZ-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR K   1
THR K  21
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.52A 4qvvH-4qv9K:
27.5		 4qvvH-4qv9K:
29.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVV_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 8 THR K   1
THR K  21
LYS K  33
GLY K  47
GLY K  48
 None
 0.49A 4qvvK-4qv9K:
38.9
4qvvL-4qv9K:
23.4		 4qvvK-4qv9K:
99.06
4qvvL-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR K   1
THR K  21
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.51A 4qvvV-4qv9K:
29.2		 4qvvV-4qv9K:
29.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVV_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 8 THR K   1
THR K  21
LYS K  33
GLY K  47
GLY K  48
 None
 0.48A 4qvvY-4qv9K:
38.9
4qvvZ-4qv9K:
23.2		 4qvvY-4qv9K:
99.06
4qvvZ-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.52A 4qvwV-4qv9K:
29.3
4qvwb-4qv9K:
28.9		 4qvwV-4qv9K:
29.29
4qvwb-4qv9K:
27.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 11 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
 None
 0.50A 4qvwK-4qv9K:
39.1
4qvwL-4qv9K:
23.5		 4qvwK-4qv9K:
99.06
4qvwL-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.51A 4qvwH-4qv9K:
27.5
4qvwN-4qv9K:
28.9		 4qvwH-4qv9K:
29.29
4qvwN-4qv9K:
27.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 11 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
 None
 0.50A 4qvwY-4qv9K:
39.1
4qvwZ-4qv9K:
23.3		 4qvwY-4qv9K:
99.06
4qvwZ-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR K   1
THR K  21
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.50A 4qvyH-4qv9K:
27.5		 4qvyH-4qv9K:
29.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 10 ALA K  20
THR K  21
ALA K  22
ALA K  27
VAL K  31
LYS K  33
GLY K  47
 None
 0.81A 4qvyK-4qv9K:
39.5
4qvyL-4qv9K:
23.5		 4qvyK-4qv9K:
99.06
4qvyL-4qv9K:
21.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 10 THR K   1
ALA K  20
THR K  21
ALA K  22
ALA K  27
VAL K  31
LYS K  33
GLY K  48
 None
 0.41A 4qvyK-4qv9K:
39.5
4qvyL-4qv9K:
23.5		 4qvyK-4qv9K:
99.06
4qvyL-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.36A 4qvyV-4qv9K:
29.3
4qvyW-4qv9K:
25.6		 4qvyV-4qv9K:
29.29
4qvyW-4qv9K:
27.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 10 ALA K  20
THR K  21
ALA K  22
ALA K  27
VAL K  31
LYS K  33
GLY K  47
 None
 0.81A 4qvyY-4qv9K:
39.5
4qvyZ-4qv9K:
23.3		 4qvyY-4qv9K:
99.06
4qvyZ-4qv9K:
21.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 10 THR K   1
ALA K  20
THR K  21
ALA K  22
ALA K  27
VAL K  31
LYS K  33
GLY K  48
 None
 0.42A 4qvyY-4qv9K:
39.5
4qvyZ-4qv9K:
23.3		 4qvyY-4qv9K:
99.06
4qvyZ-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.50A 4qw0V-4qv9K:
29.2
4qw0b-4qv9K:
28.9		 4qw0V-4qv9K:
29.29
4qw0b-4qv9K:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.36A 4qw0H-4qv9K:
27.5
4qw0I-4qv9K:
25.4		 4qw0H-4qv9K:
29.29
4qw0I-4qv9K:
27.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 7 THR K   1
ALA K  20
THR K  21
ALA K  22
LYS K  33
 None
 0.22A 4qw0K-4qv9K:
39.4		 4qw0K-4qv9K:
98.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.50A 4qw0H-4qv9K:
27.5
4qw0N-4qv9K:
28.9		 4qw0H-4qv9K:
29.29
4qw0N-4qv9K:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.34A 4qw0V-4qv9K:
29.2
4qw0W-4qv9K:
25.5		 4qw0V-4qv9K:
29.29
4qw0W-4qv9K:
27.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 7 THR K   1
ALA K  20
THR K  21
ALA K  22
LYS K  33
 None
 0.24A 4qw0Y-4qv9K:
39.4		 4qw0Y-4qv9K:
98.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.54A 4qw1V-4qv9K:
29.2
4qw1b-4qv9K:
28.9		 4qw1V-4qv9K:
29.29
4qw1b-4qv9K:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.36A 4qw1H-4qv9K:
27.5
4qw1I-4qv9K:
25.6		 4qw1H-4qv9K:
29.29
4qw1I-4qv9K:
27.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
 None
 0.82A 4qw1K-4qv9K:
39.2
4qw1L-4qv9K:
23.6		 4qw1K-4qv9K:
99.06
4qw1L-4qv9K:
21.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 11 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.54A 4qw1K-4qv9K:
39.2
4qw1L-4qv9K:
23.6		 4qw1K-4qv9K:
99.06
4qw1L-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.54A 4qw1H-4qv9K:
27.5
4qw1N-4qv9K:
28.9		 4qw1H-4qv9K:
29.29
4qw1N-4qv9K:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.36A 4qw1V-4qv9K:
29.2
4qw1W-4qv9K:
25.6		 4qw1V-4qv9K:
29.29
4qw1W-4qv9K:
27.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 10 ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
 None
 0.81A 4qw1Y-4qv9K:
39.2
4qw1Z-4qv9K:
23.3		 4qw1Y-4qv9K:
99.06
4qw1Z-4qv9K:
21.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 10 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.53A 4qw1Y-4qv9K:
39.2
4qw1Z-4qv9K:
23.3		 4qw1Y-4qv9K:
99.06
4qw1Z-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.51A 4qw3V-4qv9K:
29.2
4qw3b-4qv9K:
28.9		 4qw3V-4qv9K:
29.29
4qw3b-4qv9K:
27.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 10 ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
 None
 0.80A 4qw3K-4qv9K:
38.3
4qw3L-4qv9K:
23.4		 4qw3K-4qv9K:
100.00
4qw3L-4qv9K:
21.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 10 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.52A 4qw3K-4qv9K:
38.3
4qw3L-4qv9K:
23.4		 4qw3K-4qv9K:
100.00
4qw3L-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.51A 4qw3H-4qv9K:
27.4
4qw3N-4qv9K:
28.8		 4qw3H-4qv9K:
29.29
4qw3N-4qv9K:
27.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 10 ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
 None
 0.80A 4qw3Y-4qv9K:
38.3
4qw3Z-4qv9K:
23.1		 4qw3Y-4qv9K:
100.00
4qw3Z-4qv9K:
21.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 10 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.52A 4qw3Y-4qv9K:
38.3
4qw3Z-4qv9K:
23.1		 4qw3Y-4qv9K:
100.00
4qw3Z-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.55A 4qwuV-4qv9K:
29.2
4qwub-4qv9K:
28.9		 4qwuV-4qv9K:
29.29
4qwub-4qv9K:
27.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QWU_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 9 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
 None
 0.48A 4qwuK-4qv9K:
38.6
4qwuL-4qv9K:
23.4		 4qwuK-4qv9K:
99.06
4qwuL-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.56A 4qwuH-4qv9K:
27.4
4qwuN-4qv9K:
28.9		 4qwuH-4qv9K:
29.29
4qwuN-4qv9K:
27.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QWU_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 9 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
 None
 0.53A 4qwuY-4qv9K:
38.6
4qwuZ-4qv9K:
23.4		 4qwuY-4qv9K:
99.06
4qwuZ-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.50A 5bxnV-4qv9K:
29.1
5bxnb-4qv9K:
28.9		 5bxnV-4qv9K:
28.87
5bxnb-4qv9K:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.35A 5bxnH-4qv9K:
28.9
5bxnI-4qv9K:
25.7		 5bxnH-4qv9K:
28.87
5bxnI-4qv9K:
27.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
 None
 0.80A 5bxnK-4qv9K:
38.8
5bxnL-4qv9K:
23.3		 5bxnK-4qv9K:
99.53
5bxnL-4qv9K:
21.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 11 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.51A 5bxnK-4qv9K:
38.8
5bxnL-4qv9K:
23.3		 5bxnK-4qv9K:
99.53
5bxnL-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.50A 5bxnH-4qv9K:
28.9
5bxnN-4qv9K:
28.9		 5bxnH-4qv9K:
28.87
5bxnN-4qv9K:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR K   1
THR K  21
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.52A 5bxnV-4qv9K:
29.1
5bxnW-4qv9K:
25.7		 5bxnV-4qv9K:
28.87
5bxnW-4qv9K:
27.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
 None
 0.80A 5bxnY-4qv9K:
38.8
5bxnZ-4qv9K:
23.3		 5bxnY-4qv9K:
99.53
5bxnZ-4qv9K:
21.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 11 THR K   1
ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.52A 5bxnY-4qv9K:
38.8
5bxnZ-4qv9K:
23.3		 5bxnY-4qv9K:
99.53
5bxnZ-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.53A 5cz7H-4qv9K:
27.5
5cz7N-4qv9K:
28.9		 5cz7H-4qv9K:
29.29
5cz7N-4qv9K:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.35A 5cz7V-4qv9K:
29.3
5cz7W-4qv9K:
25.6		 5cz7V-4qv9K:
29.29
5cz7W-4qv9K:
27.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.51A 5d0xV-4qv9K:
29.2
5d0xb-4qv9K:
28.8		 5d0xV-4qv9K:
29.29
5d0xb-4qv9K:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR K   1
THR K  21
LYS K  33
ALA K  46
ALA K  49
 None
 0.53A 5d0xH-4qv9K:
27.5
5d0xI-4qv9K:
25.5		 5d0xH-4qv9K:
29.29
5d0xI-4qv9K:
27.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 9 ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
 None
 0.81A 5d0xK-4qv9K:
38.6
5d0xL-4qv9K:
23.5		 5d0xK-4qv9K:
99.06
5d0xL-4qv9K:
21.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 9 ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.51A 5d0xK-4qv9K:
38.6
5d0xL-4qv9K:
23.5		 5d0xK-4qv9K:
99.06
5d0xL-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.50A 5d0xH-4qv9K:
27.5
5d0xN-4qv9K:
28.8		 5d0xH-4qv9K:
29.29
5d0xN-4qv9K:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR K   1
THR K  21
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.52A 5d0xV-4qv9K:
29.2		 5d0xV-4qv9K:
29.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 9 ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
 None
 0.81A 5d0xY-4qv9K:
38.6
5d0xZ-4qv9K:
23.3		 5d0xY-4qv9K:
99.06
5d0xZ-4qv9K:
21.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 9 ALA K  20
THR K  21
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.51A 5d0xY-4qv9K:
38.6
5d0xZ-4qv9K:
23.3		 5d0xY-4qv9K:
99.06
5d0xZ-4qv9K:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 LEU K  59
THR K  99
GLY K  43
ILE K 101
GLY K 130
 None
 1.01A 5d4uC-4qv9K:
undetectable		 5d4uC-4qv9K:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 LEU K  59
THR K  99
GLY K  43
ILE K 101
GLY K 130
 None
 0.97A 5d4uD-4qv9K:
undetectable		 5d4uD-4qv9K:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		4 / 4 LEU K  42
ILE K  12
GLY K  43
ILE K 112
 None
 0.80A 5dzk3-4qv9K:
undetectable
5dzkm-4qv9K:
undetectable		 5dzk3-4qv9K:
4.76
5dzkm-4qv9K:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		4 / 5 ILE K  12
GLY K  43
ILE K 112
LEU K  42
 None
 0.72A 5dzkB-4qv9K:
undetectable
5dzkI-4qv9K:
undetectable
5dzkW-4qv9K:
undetectable		 5dzkB-4qv9K:
22.40
5dzkI-4qv9K:
22.13
5dzkW-4qv9K:
4.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		4 / 5 ILE K  12
GLY K  43
ILE K 112
LEU K  42
 None
 0.71A 5dzki-4qv9K:
undetectable
5dzkj-4qv9K:
undetectable
5dzkx-4qv9K:
undetectable		 5dzki-4qv9K:
22.13
5dzkj-4qv9K:
22.13
5dzkx-4qv9K:
4.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		4 / 5 ILE K  12
GLY K  43
ILE K 112
LEU K  42
 None
 0.75A 5dzkd-4qv9K:
undetectable
5dzkk-4qv9K:
undetectable
5dzky-4qv9K:
undetectable		 5dzkd-4qv9K:
22.40
5dzkk-4qv9K:
22.13
5dzky-4qv9K:
4.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		4 / 4 ILE K  12
GLY K  43
ILE K 112
LEU K  42
 None
 0.78A 5dzkl-4qv9K:
undetectable
5dzkz-4qv9K:
undetectable		 5dzkl-4qv9K:
22.13
5dzkz-4qv9K:
4.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_B_010B607_0
(HNL ISOENZYME 5)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 10 ALA K 163
ALA K 165
VAL K 193
LEU K   4
VAL K 175
 None
 1.36A 5eb5B-4qv9K:
undetectable		 5eb5B-4qv9K:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_C_ACTC1740_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		4 / 4 VAL K  76
GLU K 108
GLY K 103
LEU K  41
 None
 1.22A 5g5gC-4qv9K:
undetectable		 5g5gC-4qv9K:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.33A 5l5fH-4qv9K:
27.5
5l5fI-4qv9K:
25.6		 5l5fH-4qv9K:
29.29
5l5fI-4qv9K:
27.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.32A 5l5fV-4qv9K:
29.3
5l5fW-4qv9K:
25.6		 5l5fV-4qv9K:
29.29
5l5fW-4qv9K:
27.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.51A 5l5zV-4qv9K:
29.3
5l5zb-4qv9K:
28.8		 5l5zV-4qv9K:
29.29
5l5zb-4qv9K:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR K   2
THR K   1
SER K 174
GLY K 173
ALA K 165
 None
 0.95A 5l5zV-4qv9K:
29.3
5l5zb-4qv9K:
28.8		 5l5zV-4qv9K:
29.29
5l5zb-4qv9K:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 12 THR K   1
THR K  21
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.52A 5l5zH-4qv9K:
27.5
5l5zI-4qv9K:
25.7		 5l5zH-4qv9K:
29.29
5l5zI-4qv9K:
27.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 9 ALA K  20
THR K  21
ALA K  22
ALA K  27
GLY K  48
 None
 0.90A 5l5zK-4qv9K:
38.2
5l5zL-4qv9K:
23.3		 5l5zK-4qv9K:
82.08
5l5zL-4qv9K:
23.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 9 THR K   1
ALA K  20
THR K  21
ALA K  22
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.47A 5l5zK-4qv9K:
38.2
5l5zL-4qv9K:
23.3		 5l5zK-4qv9K:
82.08
5l5zL-4qv9K:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.51A 5l5zH-4qv9K:
27.5
5l5zN-4qv9K:
28.8		 5l5zH-4qv9K:
29.29
5l5zN-4qv9K:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR K   2
THR K   1
SER K 174
GLY K 173
ALA K 165
 None
 0.95A 5l5zH-4qv9K:
27.5
5l5zN-4qv9K:
28.8		 5l5zH-4qv9K:
29.29
5l5zN-4qv9K:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 12 THR K   1
THR K  21
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.51A 5l5zV-4qv9K:
29.3
5l5zW-4qv9K:
25.7		 5l5zV-4qv9K:
29.29
5l5zW-4qv9K:
27.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 9 ALA K  20
THR K  21
ALA K  22
ALA K  27
GLY K  48
 None
 0.90A 5l5zY-4qv9K:
38.2
5l5zZ-4qv9K:
23.3		 5l5zY-4qv9K:
82.08
5l5zZ-4qv9K:
23.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 9 THR K   1
ALA K  20
THR K  21
ALA K  22
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.48A 5l5zY-4qv9K:
38.2
5l5zZ-4qv9K:
23.3		 5l5zY-4qv9K:
82.08
5l5zZ-4qv9K:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.49A 5l66V-4qv9K:
29.2
5l66b-4qv9K:
28.9		 5l66V-4qv9K:
29.29
5l66b-4qv9K:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.32A 5l66H-4qv9K:
27.5
5l66I-4qv9K:
25.7		 5l66H-4qv9K:
29.29
5l66I-4qv9K:
27.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 10 THR K   1
ALA K  20
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.40A 5l66K-4qv9K:
37.7
5l66L-4qv9K:
23.6		 5l66K-4qv9K:
77.36
5l66L-4qv9K:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.50A 5l66H-4qv9K:
27.5
5l66N-4qv9K:
28.9		 5l66H-4qv9K:
29.29
5l66N-4qv9K:
27.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR K   1
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.32A 5l66V-4qv9K:
29.2
5l66W-4qv9K:
25.7		 5l66V-4qv9K:
29.29
5l66W-4qv9K:
27.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 10 THR K   1
ALA K  20
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.41A 5l66Y-4qv9K:
37.7
5l66Z-4qv9K:
23.3		 5l66Y-4qv9K:
77.36
5l66Z-4qv9K:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.65A 5lf3b-4qv9K:
28.6		 5lf3b-4qv9K:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR K   2
THR K   1
SER K 174
GLY K 173
ALA K 165
 None
 0.97A 5lf3b-4qv9K:
28.6		 5lf3b-4qv9K:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 10 THR K   1
ALA K  20
THR K  21
ALA K  46
GLY K  47
ALA K  49
 None
 0.57A 5lf3H-4qv9K:
30.2
5lf3I-4qv9K:
25.4		 5lf3H-4qv9K:
28.09
5lf3I-4qv9K:
25.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		9 / 11 THR K   1
ALA K  20
THR K  21
ALA K  22
LYS K  33
GLY K  47
GLY K  48
ALA K  49
TYR K 170
 None
 0.63A 5lf3K-4qv9K:
35.2
5lf3L-4qv9K:
24.4		 5lf3K-4qv9K:
64.90
5lf3L-4qv9K:
26.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 11 THR K   1
ALA K  20
THR K  21
ALA K  22
LYS K  33
GLY K  47
TYR K 170
 None
 0.91A 5lf3K-4qv9K:
35.2
5lf3L-4qv9K:
24.4		 5lf3K-4qv9K:
64.90
5lf3L-4qv9K:
26.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR K   1
THR K  21
LYS K  33
GLY K  47
ALA K  49
 None
 0.64A 5lf3N-4qv9K:
28.6		 5lf3N-4qv9K:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR K   2
THR K   1
SER K 174
GLY K 173
ALA K 165
 None
 0.97A 5lf3N-4qv9K:
28.6		 5lf3N-4qv9K:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 10 THR K   1
ALA K  20
THR K  21
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.52A 5lf3V-4qv9K:
30.2
5lf3W-4qv9K:
25.4		 5lf3V-4qv9K:
28.09
5lf3W-4qv9K:
25.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		9 / 11 THR K   1
ALA K  20
THR K  21
ALA K  22
LYS K  33
GLY K  47
GLY K  48
ALA K  49
TYR K 170
 None
 0.62A 5lf3Y-4qv9K:
35.2
5lf3Z-4qv9K:
24.4		 5lf3Y-4qv9K:
64.90
5lf3Z-4qv9K:
26.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 11 THR K   1
ALA K  20
THR K  21
ALA K  22
LYS K  33
GLY K  47
TYR K 170
 None
 0.89A 5lf3Y-4qv9K:
35.2
5lf3Z-4qv9K:
24.4		 5lf3Y-4qv9K:
64.90
5lf3Z-4qv9K:
26.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 12 THR K   1
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.75A 5lf7V-4qv9K:
30.2
5lf7b-4qv9K:
28.7		 5lf7V-4qv9K:
28.09
5lf7b-4qv9K:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR K   2
THR K   1
SER K 174
GLY K 173
ALA K 165
 None
 0.97A 5lf7V-4qv9K:
30.2
5lf7b-4qv9K:
28.7		 5lf7V-4qv9K:
28.09
5lf7b-4qv9K:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR K   1
ALA K  20
THR K  21
ALA K  46
GLY K  47
ALA K  49
 None
 0.54A 5lf7H-4qv9K:
30.2
5lf7I-4qv9K:
25.4		 5lf7H-4qv9K:
28.09
5lf7I-4qv9K:
25.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		9 / 11 THR K   1
ALA K  20
THR K  21
ALA K  22
VAL K  31
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.69A 5lf7K-4qv9K:
35.1
5lf7L-4qv9K:
24.5		 5lf7K-4qv9K:
64.90
5lf7L-4qv9K:
26.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR K   1
ALA K  20
THR K  21
VAL K  31
LYS K  33
GLY K  47
 None
 0.94A 5lf7K-4qv9K:
35.1
5lf7L-4qv9K:
24.5		 5lf7K-4qv9K:
64.90
5lf7L-4qv9K:
26.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 12 THR K   1
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.75A 5lf7H-4qv9K:
30.2
5lf7N-4qv9K:
28.6		 5lf7H-4qv9K:
28.09
5lf7N-4qv9K:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR K   2
THR K   1
SER K 174
GLY K 173
ALA K 165
 None
 0.98A 5lf7H-4qv9K:
30.2
5lf7N-4qv9K:
28.6		 5lf7H-4qv9K:
28.09
5lf7N-4qv9K:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR K   1
ALA K  20
THR K  21
ALA K  46
GLY K  47
ALA K  49
 None
 0.53A 5lf7V-4qv9K:
30.2
5lf7W-4qv9K:
25.5		 5lf7V-4qv9K:
28.09
5lf7W-4qv9K:
25.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		9 / 11 THR K   1
ALA K  20
THR K  21
ALA K  22
VAL K  31
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.68A 5lf7Y-4qv9K:
35.1
5lf7Z-4qv9K:
24.5		 5lf7Y-4qv9K:
64.90
5lf7Z-4qv9K:
26.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR K   1
ALA K  20
THR K  21
VAL K  31
LYS K  33
GLY K  47
 None
 0.93A 5lf7Y-4qv9K:
35.1
5lf7Z-4qv9K:
24.5		 5lf7Y-4qv9K:
64.90
5lf7Z-4qv9K:
26.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 12 THR K   1
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.59A 6hwdV-4qv9K:
29.1
6hwdb-4qv9K:
28.8		 6hwdV-4qv9K:
21.43
6hwdb-4qv9K:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 12 THR K   1
ALA K  27
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.53A 6hwdH-4qv9K:
27.4
6hwdI-4qv9K:
25.6		 6hwdH-4qv9K:
21.43
6hwdI-4qv9K:
18.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		9 / 11 THR K   1
ALA K  20
THR K  21
ALA K  22
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.60A 6hwdK-4qv9K:
37.9
6hwdL-4qv9K:
23.6		 6hwdK-4qv9K:
98.75
6hwdL-4qv9K:
17.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR K   1
ALA K  20
THR K  21
ALA K  22
LYS K  33
GLY K  47
 None
 0.92A 6hwdK-4qv9K:
37.9
6hwdL-4qv9K:
23.6		 6hwdK-4qv9K:
98.75
6hwdL-4qv9K:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 12 THR K   1
THR K  21
ALA K  27
LYS K  33
GLY K  47
ALA K  49
 None
 0.59A 6hwdH-4qv9K:
27.4
6hwdN-4qv9K:
28.8		 6hwdH-4qv9K:
21.43
6hwdN-4qv9K:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR K   1
ALA K  27
LYS K  33
ALA K  46
GLY K  47
ALA K  49
 None
 0.52A 6hwdV-4qv9K:
29.1		 6hwdV-4qv9K:
21.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		9 / 11 THR K   1
ALA K  20
THR K  21
ALA K  22
ALA K  27
LYS K  33
GLY K  47
GLY K  48
ALA K  49
 None
 0.60A 6hwdY-4qv9K:
37.8
6hwdZ-4qv9K:
23.4		 6hwdY-4qv9K:
98.75
6hwdZ-4qv9K:
17.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 4qv9 PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR K   1
ALA K  20
THR K  21
ALA K  22
LYS K  33
GLY K  47
 None
 0.92A 6hwdY-4qv9K:
37.8
6hwdZ-4qv9K:
23.4		 6hwdY-4qv9K:
98.75
6hwdZ-4qv9K:
17.31