SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qvr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 4qvr UNCHARACTERIZED
HYPOTHETICAL PROTEIN
FTT_1539C
(Francisella
tularensis) 		5 / 12 GLN A 311
ARG A 295
GLY A 310
ALA A 121
GLN A 126
 None
 1.10A 3v3oA-4qvrA:
undetectable		 3v3oA-4qvrA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4qvr UNCHARACTERIZED
HYPOTHETICAL PROTEIN
FTT_1539C
(Francisella
tularensis) 		4 / 8 GLY A 244
LEU A  74
VAL A  77
TYR A  81
 None
 0.45A 4fgzB-4qvrA:
undetectable		 4fgzB-4qvrA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4qvr UNCHARACTERIZED
HYPOTHETICAL PROTEIN
FTT_1539C
(Francisella
tularensis) 		4 / 5 ILE A 381
LEU A 385
GLU A 128
VAL A 245
 None
 1.03A 4nkxB-4qvrA:
undetectable		 4nkxB-4qvrA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_B_NOVB2000_1
(DNA GYRASE SUBUNIT B)		 4qvr UNCHARACTERIZED
HYPOTHETICAL PROTEIN
FTT_1539C
(Francisella
tularensis) 		5 / 12 SER A 361
ILE A 381
GLN A 126
ILE A 130
SER A 134
 None
 1.32A 4uroB-4qvrA:
undetectable		 4uroB-4qvrA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 4qvr UNCHARACTERIZED
HYPOTHETICAL PROTEIN
FTT_1539C
(Francisella
tularensis) 		3 / 3 ALA A 336
ASN A 339
LEU A 340
 None
 0.33A 5i1nB-4qvrA:
undetectable		 5i1nB-4qvrA:
5.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4qvr UNCHARACTERIZED
HYPOTHETICAL PROTEIN
FTT_1539C
(Francisella
tularensis) 		4 / 6 LEU A 217
SER A 216
ILE A 130
PHE A 221
 None
 0.99A 5jw1A-4qvrA:
undetectable		 5jw1A-4qvrA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4qvr UNCHARACTERIZED
HYPOTHETICAL PROTEIN
FTT_1539C
(Francisella
tularensis) 		3 / 3 SER A  69
ALA A  70
THR A 100
 None
 0.47A 5n0xB-4qvrA:
undetectable		 5n0xB-4qvrA:
22.40