SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qwo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4qwo PROFILIN
(Monkeypox
virus) 		5 / 12 VAL A  23
ALA A  21
LEU A  84
ILE A  96
GLY A  63
 None
 0.76A 5hieA-4qwoA:
undetectable		 5hieA-4qwoA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4qwo PROFILIN
(Monkeypox
virus) 		5 / 11 VAL A 128
THR A  99
ASP A  24
ILE A  22
ALA A  33
 None
 1.03A 5lg3A-4qwoA:
undetectable		 5lg3A-4qwoA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 4qwo PROFILIN
(Monkeypox
virus) 		4 / 7 PRO A  60
ILE A  94
ILE A  96
ILE A  43
 None
 0.85A 5murB-4qwoA:
undetectable		 5murB-4qwoA:
20.00