SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qwp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OLT_A_SAMA501_0
(OXYGEN-INDEPENDENT
COPROPORPHYRINOGEN
III OXIDASE)		 4qwp CHITOSANASE
(Pseudomonas
sp.
A-01) 		5 / 12 THR A 206
ASP A 210
PHE A 144
TYR A 146
ALA A 129
 None
 1.24A 1oltA-4qwpA:
undetectable		 1oltA-4qwpA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 4qwp CHITOSANASE
(Pseudomonas
sp.
A-01) 		4 / 8 GLY A 154
HIS A 153
ILE A  52
HIS A 203
 GCS  A 301 (-3.3A)
None
None
GCS  A 303 ( 4.9A)
 0.94A 2x0pA-4qwpA:
undetectable		 2x0pA-4qwpA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)		 4qwp CHITOSANASE
(Pseudomonas
sp.
A-01) 		4 / 8 PHE A 189
ASP A 136
TYR A 185
LEU A 150
 None
 1.24A 3jq7B-4qwpA:
undetectable		 3jq7B-4qwpA:
22.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OLT_A_GCSA302_1
(CHITOSANASE)		 4qwp CHITOSANASE
(Pseudomonas
sp.
A-01) 		5 / 5 ARG A  45
THR A  55
THR A  58
ASP A  60
TYR A 125
 GCS  A 302 (-4.0A)
GCS  A 302 ( 4.2A)
GCS  A 302 ( 3.4A)
GCS  A 302 (-3.0A)
None
 0.14A 4oltA-4qwpA:
41.9		 4oltA-4qwpA:
99.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OLT_A_GCSA303_1
(CHITOSANASE)		 4qwp CHITOSANASE
(Pseudomonas
sp.
A-01) 		5 / 6 ILE A  41
ARG A  45
GLY A  53
VAL A 151
HIS A 203
 GCS  A 303 (-4.2A)
GCS  A 302 (-4.0A)
None
None
GCS  A 303 ( 4.9A)
 0.21A 4oltA-4qwpA:
41.9		 4oltA-4qwpA:
99.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OLT_A_GCSA304_1
(CHITOSANASE)		 4qwp CHITOSANASE
(Pseudomonas
sp.
A-01) 		4 / 4 TYR A  37
ILE A  41
THR A  48
TYR A 233
 GCS  A 303 (-4.7A)
GCS  A 303 (-4.2A)
GCS  A 303 ( 4.2A)
GCS  A 304 (-3.5A)
 0.09A 4oltA-4qwpA:
41.9		 4oltA-4qwpA:
99.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OLT_B_GCSB302_1
(CHITOSANASE)		 4qwp CHITOSANASE
(Pseudomonas
sp.
A-01) 		5 / 5 ARG A  45
THR A  55
THR A  58
ASP A  60
TYR A 125
 GCS  A 302 (-4.0A)
GCS  A 302 ( 4.2A)
GCS  A 302 ( 3.4A)
GCS  A 302 (-3.0A)
None
 0.11A 4oltB-4qwpA:
42.7		 4oltB-4qwpA:
99.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OLT_B_GCSB303_1
(CHITOSANASE)		 4qwp CHITOSANASE
(Pseudomonas
sp.
A-01) 		5 / 6 ILE A  41
ARG A  45
GLY A  53
VAL A 151
HIS A 203
 GCS  A 303 (-4.2A)
GCS  A 302 (-4.0A)
None
None
GCS  A 303 ( 4.9A)
 0.15A 4oltB-4qwpA:
42.7		 4oltB-4qwpA:
99.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OLT_B_GCSB304_1
(CHITOSANASE)		 4qwp CHITOSANASE
(Pseudomonas
sp.
A-01) 		5 / 5 TYR A  37
ILE A  41
THR A  48
HIS A 203
TYR A 233
 GCS  A 303 (-4.7A)
GCS  A 303 (-4.2A)
GCS  A 303 ( 4.2A)
GCS  A 303 ( 4.9A)
GCS  A 304 (-3.5A)
 0.13A 4oltB-4qwpA:
42.7		 4oltB-4qwpA:
99.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 4qwp CHITOSANASE
(Pseudomonas
sp.
A-01) 		4 / 8 ILE A  41
ARG A  45
GLY A  53
THR A  55
 GCS  A 303 (-4.2A)
GCS  A 302 (-4.0A)
None
GCS  A 302 ( 4.2A)
 0.20A 5hwaA-4qwpA:
10.7		 5hwaA-4qwpA:
26.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)		 4qwp CHITOSANASE
(Pseudomonas
sp.
A-01) 		5 / 7 ARG A  45
THR A  55
ASP A  60
TYR A 125
GLY A 154
 GCS  A 302 (-4.0A)
GCS  A 302 ( 4.2A)
GCS  A 302 (-3.0A)
None
GCS  A 301 (-3.3A)
 0.38A 5hwaA-4qwpA:
16.9		 5hwaA-4qwpA:
26.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)		 4qwp CHITOSANASE
(Pseudomonas
sp.
A-01) 		5 / 7 ARG A  45
THR A  58
ASP A  60
TYR A 125
GLY A 154
 GCS  A 302 (-4.0A)
GCS  A 302 ( 3.4A)
GCS  A 302 (-3.0A)
None
GCS  A 301 (-3.3A)
 1.40A 5hwaA-4qwpA:
16.9		 5hwaA-4qwpA:
26.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)		 4qwp CHITOSANASE
(Pseudomonas
sp.
A-01) 		5 / 11 PHE A  24
ARG A 193
ALA A 212
LEU A   8
ALA A 129
 None
 1.34A 6efnA-4qwpA:
undetectable		 6efnA-4qwpA:
19.18