SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qxf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HSG_B_MK1B902_2 (HIV-1 PROTEASE)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	GLY A 90 GLY A 45 PRO A 52 VAL A 51 ILE A 69	None	0.96A	1hsgB-4qxfA: undetectable	1hsgB-4qxfA: 16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIJ_B_NOVB444_2 (DNA GYRASE SUBUNIT B)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	3 / 3	ASP A 147 PHE A 149 VAL A 144	None	0.60A	1kijB-4qxfA: undetectable	1kijB-4qxfA: 19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TBF_A_VIAA501_1 (CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 9	LEU A 232 LEU A 216 VAL A 168 LEU A 182 PHE A 221	None	1.21A	1tbfA-4qxfA: undetectable	1tbfA-4qxfA: 24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZLQ_A_ACTA1502_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	4 / 5	PRO A 32 GLY A 47 ASN A 67 GLY A 45	None	0.96A	1zlqA-4qxfA: undetectable	1zlqA-4qxfA: 22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AOI_C_FRDC305_1 (POL POLYPROTEIN PEPTIDE INHIBITOR)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	4 / 5	GLY A 45 PRO A 52 VAL A 51 ILE A 69	None	0.83A	2aoiA-4qxfA: undetectable	2aoiA-4qxfA: 15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BM9_C_SAMC301_0 (CEPHALOSPORIN HYDROXYLASE CMCI)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	LEU A 62 LEU A 55 GLU A 53 ALA A 76 ALA A 100	None	1.06A	2bm9C-4qxfA: undetectable	2bm9C-4qxfA: 18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CDQ_A_SAMA1500_0 (ASPARTOKINASE)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	4 / 8	ILE A 64 SER A 44 ASP A 42 LEU A 62	None	0.96A	2cdqA-4qxfA: undetectable	2cdqA-4qxfA: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OIP_C_MTXC613_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	VAL A 120 LEU A 184 LEU A 173 PHE A 149 LEU A 155	None	1.25A	2oipC-4qxfA: undetectable	2oipC-4qxfA: 20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PYM_A_1UNA1001_1 (PROTEASE RETROPEPSIN)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	GLY A 90 GLY A 45 PRO A 52 VAL A 51 ILE A 69	None	0.83A	2pymA-4qxfA: undetectable	2pymA-4qxfA: 15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PYM_A_1UNA1001_2 (PROTEASE RETROPEPSIN)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	GLY A 90 GLY A 45 PRO A 52 VAL A 51 ILE A 69	None	0.85A	2pymB-4qxfA: undetectable	2pymB-4qxfA: 15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PYN_A_1UNA1001_1 (PROTEASE RETROPEPSIN)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	GLY A 90 GLY A 45 PRO A 52 VAL A 51 ILE A 69	None	0.85A	2pynA-4qxfA: undetectable	2pynA-4qxfA: 16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q83_B_ADNB2_1 (YTAA PROTEIN)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	4 / 6	ILE A 69 PRO A 121 LEU A 101 ILE A 96	None	0.91A	2q83B-4qxfA: undetectable	2q83B-4qxfA: 22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CYX_A_ROCA201_1 (HIV-1 PROTEASE)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	GLY A 90 GLY A 45 PRO A 52 VAL A 51 ILE A 69	None	0.76A	3cyxA-4qxfA: undetectable	3cyxA-4qxfA: 16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D1X_A_ROCA201_1 (HIV-1 PROTEASE)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	GLY A 90 GLY A 45 PRO A 52 VAL A 51 ILE A 69	None	0.82A	3d1xA-4qxfA: undetectable	3d1xA-4qxfA: 15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D1Y_A_ROCA201_1 (HIV-1 PROTEASE)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	GLY A 90 GLY A 45 PRO A 52 VAL A 51 ILE A 69	None	0.86A	3d1yA-4qxfA: undetectable	3d1yA-4qxfA: 15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EM4_A_DR7A100_1 (PROTEASE)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 11	GLY A 90 GLY A 45 PRO A 52 VAL A 51 ILE A 69	None	0.93A	3em4A-4qxfA: undetectable	3em4A-4qxfA: 17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K4V_D_ROCD201_3 (HIV-1 PROTEASE)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	GLY A 90 GLY A 45 PRO A 52 VAL A 51 ILE A 69	None	0.85A	3k4vD-4qxfA: undetectable	3k4vD-4qxfA: 15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDT_D_ROCD100_2 (PROTEASE)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	GLY A 90 GLY A 45 PRO A 52 VAL A 51 ILE A 69	None	0.85A	3ndtD-4qxfA: undetectable	3ndtD-4qxfA: 15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDU_A_ROCA101_1 (PROTEASE)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	GLY A 90 GLY A 45 PRO A 52 VAL A 51 ILE A 69	None	0.90A	3nduA-4qxfA: undetectable	3nduA-4qxfA: 15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDU_A_ROCA101_2 (PROTEASE)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	GLY A 90 GLY A 45 PRO A 52 VAL A 51 ILE A 69	None	0.89A	3nduB-4qxfA: undetectable	3nduB-4qxfA: 15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDU_D_ROCD100_2 (PROTEASE)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	GLY A 90 GLY A 45 PRO A 52 VAL A 51 ILE A 69	None	0.85A	3nduD-4qxfA: undetectable	3nduD-4qxfA: 15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NT1_B_NPSB4_1 (PROSTAGLANDIN-ENDOPE ROXIDE SYNTHASE 2)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	LEU A 104 LEU A 88 GLY A 75 ALA A 76 LEU A 72	None	1.06A	3nt1B-4qxfA: undetectable	3nt1B-4qxfA: 21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PWR_A_ROCA401_1 (PROTEASE)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	GLY A 90 GLY A 45 PRO A 52 VAL A 51 ILE A 69	None	0.86A	3pwrA-4qxfA: undetectable	3pwrA-4qxfA: 15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TKG_B_ROCB801_1 (PROTEASE)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	GLY A 90 GLY A 45 PRO A 52 VAL A 51 ILE A 69	None	0.91A	3tkgA-4qxfA: undetectable	3tkgA-4qxfA: 16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TKG_B_ROCB801_2 (PROTEASE)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	GLY A 90 GLY A 45 PRO A 52 VAL A 51 ILE A 69	None	0.92A	3tkgB-4qxfA: undetectable	3tkgB-4qxfA: 16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TKG_C_ROCC901_1 (PROTEASE)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	GLY A 90 GLY A 45 PRO A 52 VAL A 51 ILE A 69	None	0.88A	3tkgC-4qxfA: undetectable	3tkgC-4qxfA: 16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EJ1_B_FOLB201_0 (DIHYDROFOLATE REDUCTASE)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	ILE A 267 ALA A 243 LEU A 237 PHE A 240 LEU A 279	None	1.10A	4ej1B-4qxfA: undetectable	4ej1B-4qxfA: 18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GKH_C_KANC301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 11	GLN A 113 ARG A 135 ASN A 187 ASP A 161 HIS A 140	None	1.46A	4gkhC-4qxfA: 0.0 4gkhD-4qxfA: 0.0	4gkhC-4qxfA: 22.15 4gkhD-4qxfA: 22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4N09_A_ADNA401_2 (ADENOSINE KINASE)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	4 / 4	LEU A 152 SER A 148 LEU A 158 LEU A 128	None	1.08A	4n09A-4qxfA: undetectable	4n09A-4qxfA: 22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YIA_B_IMNB401_1 (THYROXINE-BINDING GLOBULIN)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 10	SER A 215 LEU A 206 LEU A 184 SER A 191 LEU A 173	None	1.19A	4yiaA-4qxfA: undetectable	4yiaA-4qxfA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EAJ_B_FOLB201_0 (DIHYDROFOLATE REDUCTASE)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	PHE A 77 ILE A 69 LEU A 72 PRO A 73 THR A 59	None	1.09A	5eajB-4qxfA: undetectable	5eajB-4qxfA: 18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L8D_B_ACTB601_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	3 / 3	THR A 119 PRO A 145 ASP A 147	None	0.91A	5l8dB-4qxfA: undetectable	5l8dB-4qxfA: 22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MWU_B_ACTB601_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	3 / 3	THR A 119 PRO A 145 ASP A 147	None	0.91A	5mwuB-4qxfA: undetectable	5mwuB-4qxfA: 22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1F_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	4 / 6	LEU A 160 ARG A 156 THR A 178 LEU A 176	None	1.06A	5x1fA-4qxfA: undetectable 5x1fJ-4qxfA: undetectable	5x1fA-4qxfA: 19.16 5x1fJ-4qxfA: 11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_F_TA1F502_1 (TUBULIN BETA CHAIN)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	LEU A 93 ALA A 124 LEU A 117 GLN A 113 LEU A 134	None	1.20A	6ew0F-4qxfA: undetectable	6ew0F-4qxfA: 14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_G_TA1G501_1 (TUBULIN BETA CHAIN)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	5 / 12	LEU A 93 ALA A 124 LEU A 117 GLN A 113 LEU A 134	None	1.20A	6ew0G-4qxfA: undetectable	6ew0G-4qxfA: 14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F88_A_STRA502_1 (CYTOCHROME P450 CYP260A1)	4qxf	LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B (Eptatretus burgeri; Homo sapiens)	4 / 6	PHE A 77 LEU A 101 ALA A 100 ASN A 91	None	1.01A	6f88A-4qxfA: undetectable	6f88A-4qxfA: 13.06

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1HSG_B_MK1B902_2","HIV-1 PROTEASE","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"GLY A  90;GLY A  45;PRO A  52;VAL A  51;ILE A  69","None","0.96A","1hsgB-4qxfA:undetectable","1hsgB-4qxfA:16.06"],["1KIJ_B_NOVB444_2","DNA GYRASE SUBUNIT B","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",3,"ASP A 147;PHE A 149;VAL A 144","None","0.60A","1kijB-4qxfA:undetectable","1kijB-4qxfA:19.29"],["1TBF_A_VIAA501_1","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"LEU A 232;LEU A 216;VAL A 168;LEU A 182;PHE A 221","None","1.21A","1tbfA-4qxfA:undetectable","1tbfA-4qxfA:24.32"],["1ZLQ_A_ACTA1502_0","NICKEL-BINDING PERIPLASMIC PROTEIN","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",4,"PRO A  32;GLY A  47;ASN A  67;GLY A  45","None","0.96A","1zlqA-4qxfA:undetectable","1zlqA-4qxfA:22.24"],["2AOI_C_FRDC305_1","POL POLYPROTEIN;PEPTIDE INHIBITOR","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",4,"GLY A  45;PRO A  52;VAL A  51;ILE A  69","None","0.83A","2aoiA-4qxfA:undetectable","2aoiA-4qxfA:15.33"],["2BM9_C_SAMC301_0","CEPHALOSPORIN HYDROXYLASE CMCI","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"LEU A  62;LEU A  55;GLU A  53;ALA A  76;ALA A 100","None","1.06A","2bm9C-4qxfA:undetectable","2bm9C-4qxfA:18.99"],["2CDQ_A_SAMA1500_0","ASPARTOKINASE","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",4,"ILE A  64;SER A  44;ASP A  42;LEU A  62","None","0.96A","2cdqA-4qxfA:undetectable","2cdqA-4qxfA:21.43"],["2OIP_C_MTXC613_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"VAL A 120;LEU A 184;LEU A 173;PHE A 149;LEU A 155","None","1.25A","2oipC-4qxfA:undetectable","2oipC-4qxfA:20.11"],["2PYM_A_1UNA1001_1","PROTEASE RETROPEPSIN","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"GLY A  90;GLY A  45;PRO A  52;VAL A  51;ILE A  69","None","0.83A","2pymA-4qxfA:undetectable","2pymA-4qxfA:15.69"],["2PYM_A_1UNA1001_2","PROTEASE RETROPEPSIN;PROTEASE RETROPEPSIN","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"GLY A  90;GLY A  45;PRO A  52;VAL A  51;ILE A  69","None","0.85A","2pymB-4qxfA:undetectable","2pymB-4qxfA:15.69"],["2PYN_A_1UNA1001_1","PROTEASE RETROPEPSIN","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"GLY A  90;GLY A  45;PRO A  52;VAL A  51;ILE A  69","None","0.85A","2pynA-4qxfA:undetectable","2pynA-4qxfA:16.06"],["2Q83_B_ADNB2_1","YTAA PROTEIN","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",4,"ILE A  69;PRO A 121;LEU A 101;ILE A  96","None","0.91A","2q83B-4qxfA:undetectable","2q83B-4qxfA:22.31"],["3CYX_A_ROCA201_1","HIV-1 PROTEASE","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"GLY A  90;GLY A  45;PRO A  52;VAL A  51;ILE A  69","None","0.76A","3cyxA-4qxfA:undetectable","3cyxA-4qxfA:16.36"],["3D1X_A_ROCA201_1","HIV-1 PROTEASE","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"GLY A  90;GLY A  45;PRO A  52;VAL A  51;ILE A  69","None","0.82A","3d1xA-4qxfA:undetectable","3d1xA-4qxfA:15.33"],["3D1Y_A_ROCA201_1","HIV-1 PROTEASE","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"GLY A  90;GLY A  45;PRO A  52;VAL A  51;ILE A  69","None","0.86A","3d1yA-4qxfA:undetectable","3d1yA-4qxfA:15.69"],["3EM4_A_DR7A100_1","PROTEASE","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"GLY A  90;GLY A  45;PRO A  52;VAL A  51;ILE A  69","None","0.93A","3em4A-4qxfA:undetectable","3em4A-4qxfA:17.45"],["3K4V_D_ROCD201_3","HIV-1 PROTEASE","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"GLY A  90;GLY A  45;PRO A  52;VAL A  51;ILE A  69","None","0.85A","3k4vD-4qxfA:undetectable","3k4vD-4qxfA:15.33"],["3NDT_D_ROCD100_2","PROTEASE","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"GLY A  90;GLY A  45;PRO A  52;VAL A  51;ILE A  69","None","0.85A","3ndtD-4qxfA:undetectable","3ndtD-4qxfA:15.22"],["3NDU_A_ROCA101_1","PROTEASE","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"GLY A  90;GLY A  45;PRO A  52;VAL A  51;ILE A  69","None","0.90A","3nduA-4qxfA:undetectable","3nduA-4qxfA:15.22"],["3NDU_A_ROCA101_2","PROTEASE;PROTEASE","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"GLY A  90;GLY A  45;PRO A  52;VAL A  51;ILE A  69","None","0.89A","3nduB-4qxfA:undetectable","3nduB-4qxfA:15.22"],["3NDU_D_ROCD100_2","PROTEASE","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"GLY A  90;GLY A  45;PRO A  52;VAL A  51;ILE A  69","None","0.85A","3nduD-4qxfA:undetectable","3nduD-4qxfA:15.22"],["3NT1_B_NPSB4_1","PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE 2","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"LEU A 104;LEU A  88;GLY A  75;ALA A  76;LEU A  72","None","1.06A","3nt1B-4qxfA:undetectable","3nt1B-4qxfA:21.55"],["3PWR_A_ROCA401_1","PROTEASE","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"GLY A  90;GLY A  45;PRO A  52;VAL A  51;ILE A  69","None","0.86A","3pwrA-4qxfA:undetectable","3pwrA-4qxfA:15.33"],["3TKG_B_ROCB801_1","PROTEASE;PROTEASE","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"GLY A  90;GLY A  45;PRO A  52;VAL A  51;ILE A  69","None","0.91A","3tkgA-4qxfA:undetectable","3tkgA-4qxfA:16.10"],["3TKG_B_ROCB801_2","PROTEASE","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"GLY A  90;GLY A  45;PRO A  52;VAL A  51;ILE A  69","None","0.92A","3tkgB-4qxfA:undetectable","3tkgB-4qxfA:16.10"],["3TKG_C_ROCC901_1","PROTEASE","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"GLY A  90;GLY A  45;PRO A  52;VAL A  51;ILE A  69","None","0.88A","3tkgC-4qxfA:undetectable","3tkgC-4qxfA:16.10"],["4EJ1_B_FOLB201_0","DIHYDROFOLATE REDUCTASE","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"ILE A 267;ALA A 243;LEU A 237;PHE A 240;LEU A 279","None","1.10A","4ej1B-4qxfA:undetectable","4ej1B-4qxfA:18.94"],["4GKH_C_KANC301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB;AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"GLN A 113;ARG A 135;ASN A 187;ASP A 161;HIS A 140","None","1.46A","4gkhC-4qxfA:0.0;4gkhD-4qxfA:0.0","4gkhC-4qxfA:22.15;4gkhD-4qxfA:22.15"],["4N09_A_ADNA401_2","ADENOSINE KINASE","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",4,"LEU A 152;SER A 148;LEU A 158;LEU A 128","None","1.08A","4n09A-4qxfA:undetectable","4n09A-4qxfA:22.42"],["4YIA_B_IMNB401_1","THYROXINE-BINDING GLOBULIN;THYROXINE-BINDING GLOBULIN","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"SER A 215;LEU A 206;LEU A 184;SER A 191;LEU A 173","None","1.19A","4yiaA-4qxfA:undetectable","4yiaA-4qxfA:22.22"],["5EAJ_B_FOLB201_0","DIHYDROFOLATE REDUCTASE","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"PHE A  77;ILE A  69;LEU A  72;PRO A  73;THR A  59","None","1.09A","5eajB-4qxfA:undetectable","5eajB-4qxfA:18.60"],["5L8D_B_ACTB601_0","NICKEL-BINDING PERIPLASMIC PROTEIN","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",3,"THR A 119;PRO A 145;ASP A 147","None","0.91A","5l8dB-4qxfA:undetectable","5l8dB-4qxfA:22.24"],["5MWU_B_ACTB601_0","NICKEL-BINDING PERIPLASMIC PROTEIN","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",3,"THR A 119;PRO A 145;ASP A 147","None","0.91A","5mwuB-4qxfA:undetectable","5mwuB-4qxfA:22.24"],["5X1F_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",4,"LEU A 160;ARG A 156;THR A 178;LEU A 176","None","1.06A","5x1fA-4qxfA:undetectable;5x1fJ-4qxfA:undetectable","5x1fA-4qxfA:19.16;5x1fJ-4qxfA:11.60"],["6EW0_F_TA1F502_1","TUBULIN BETA CHAIN","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"LEU A  93;ALA A 124;LEU A 117;GLN A 113;LEU A 134","None","1.20A","6ew0F-4qxfA:undetectable","6ew0F-4qxfA:14.67"],["6EW0_G_TA1G501_1","TUBULIN BETA CHAIN","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",5,"LEU A  93;ALA A 124;LEU A 117;GLN A 113;LEU A 134","None","1.20A","6ew0G-4qxfA:undetectable","6ew0G-4qxfA:14.67"],["6F88_A_STRA502_1","CYTOCHROME P450 CYP260A1","4qxf","LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 4, VARIABLE LYMPHOCYTE RECEPTOR B","Eptatretus burgeri;Homo sapiens",4,"PHE A  77;LEU A 101;ALA A 100;ASN A  91","None","1.01A","6f88A-4qxfA:undetectable","6f88A-4qxfA:13.06"]]