SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qxl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OLS_A_ESTA600_1 (ESTROGEN RECEPTOR BETA)	4qxl	FLAGELLAR PROTEIN FLHE (Salmonella enterica)	5 / 12	LEU A 15 LEU A 98 ALA A 101 LEU A 54 GLY A 12	None	1.11A	3olsA-4qxlA: undetectable	3olsA-4qxlA: 19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QXV_D_MTXD2000_2 (ANTI-METHOTREXATE CDR1-4 GRAFT VHH)	4qxl	FLAGELLAR PROTEIN FLHE (Salmonella enterica)	3 / 3	LEU A 58 ARG A 30 ASN A 112	None	0.65A	3qxvD-4qxlA: undetectable	3qxvD-4qxlA: 23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EIL_C_FOLC703_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	4qxl	FLAGELLAR PROTEIN FLHE (Salmonella enterica)	5 / 11	VAL A 111 ALA A 29 SER A 60 LEU A 58 VAL A 109	None	1.45A	4eilC-4qxlA: undetectable	4eilC-4qxlA: 12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KYA_C_FOLC703_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	4qxl	FLAGELLAR PROTEIN FLHE (Salmonella enterica)	5 / 10	VAL A 111 ALA A 29 SER A 60 LEU A 58 VAL A 109	None	1.50A	4kyaC-4qxlA: undetectable	4kyaC-4qxlA: 12.32

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3OLS_A_ESTA600_1","ESTROGEN RECEPTOR BETA","4qxl","FLAGELLAR PROTEIN FLHE","Salmonella enterica",5,"LEU A  15;LEU A  98;ALA A 101;LEU A  54;GLY A  12","None","1.11A","3olsA-4qxlA:undetectable","3olsA-4qxlA:19.01"],["3QXV_D_MTXD2000_2","ANTI-METHOTREXATE CDR1-4 GRAFT VHH","4qxl","FLAGELLAR PROTEIN FLHE","Salmonella enterica",3,"LEU A  58;ARG A  30;ASN A 112","None","0.65A","3qxvD-4qxlA:undetectable","3qxvD-4qxlA:23.66"],["4EIL_C_FOLC703_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","4qxl","FLAGELLAR PROTEIN FLHE","Salmonella enterica",5,"VAL A 111;ALA A  29;SER A  60;LEU A  58;VAL A 109","None","1.45A","4eilC-4qxlA:undetectable","4eilC-4qxlA:12.32"],["4KYA_C_FOLC703_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","4qxl","FLAGELLAR PROTEIN FLHE","Salmonella enterica",5,"VAL A 111;ALA A  29;SER A  60;LEU A  58;VAL A 109","None","1.50A","4kyaC-4qxlA:undetectable","4kyaC-4qxlA:12.32"]]