SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qxr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 4qxr STIMULATOR OF
INTERFERON GENES
PROTEIN
(Homo
sapiens) 		4 / 8 ASN A 242
SER A 241
VAL A 258
PHE A 221
 None
 1.26A 2wekB-4qxrA:
undetectable		 2wekB-4qxrA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 4qxr STIMULATOR OF
INTERFERON GENES
PROTEIN
(Homo
sapiens) 		4 / 8 ALA A 215
LEU A 212
ASP A 210
TYR A 261
 None
 0.94A 3qj7A-4qxrA:
undetectable
3qj7D-4qxrA:
undetectable		 3qj7A-4qxrA:
21.17
3qj7D-4qxrA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 4qxr STIMULATOR OF
INTERFERON GENES
PROTEIN
(Homo
sapiens) 		4 / 6 TYR A 240
LEU A 168
GLU A 260
LEU A 198
 None
 1.23A 5xooA-4qxrA:
undetectable		 5xooA-4qxrA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 4qxr STIMULATOR OF
INTERFERON GENES
PROTEIN
(Homo
sapiens) 		4 / 6 TYR A 240
LEU A 172
GLU A 260
LEU A 198
 None
 1.31A 5xooA-4qxrA:
undetectable		 5xooA-4qxrA:
17.47