SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qxw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_O_TRPO1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	4qxw	CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 1 (Homo sapiens)	5 / 9	GLY A 14 GLN A 80 ILE A 75 VAL A 17 VAL A 11	None	1.46A	3fi0O-4qxwA: undetectable	3fi0O-4qxwA: 15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GSS_B_EAAB211_1 (GLUTATHIONE S-TRANSFERASE P1-1)	4qxw	CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 1 (Homo sapiens)	4 / 7	VAL A 78 ILE A 45 TYR A 86 THR A 87	None	0.98A	3gssB-4qxwA: undetectable	3gssB-4qxwA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JAY_A_SAMA1101_0 (STRUCTURAL PROTEIN VP3)	4qxw	CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 1 (Homo sapiens)	5 / 12	ASN A 61 SER A 62 ARG A 43 ASP A 82 ASN A 81	None None MLA A 201 (-2.8A) None None	1.41A	3jayA-4qxwA: undetectable	3jayA-4qxwA: 7.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JB3_A_SAMA1101_0 (STRUCTURAL PROTEIN VP3)	4qxw	CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 1 (Homo sapiens)	5 / 12	ASN A 61 SER A 62 ARG A 43 ASP A 82 ASN A 81	None None MLA A 201 (-2.8A) None None	1.42A	3jb3A-4qxwA: undetectable	3jb3A-4qxwA: 7.37

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3FI0_O_TRPO1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","4qxw","CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 1","Homo sapiens",5,"GLY A  14;GLN A  80;ILE A  75;VAL A  17;VAL A  11","None","1.46A","3fi0O-4qxwA:undetectable","3fi0O-4qxwA:15.34"],["3GSS_B_EAAB211_1","GLUTATHIONE S-TRANSFERASE P1-1","4qxw","CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 1","Homo sapiens",4,"VAL A  78;ILE A  45;TYR A  86;THR A  87","None","0.98A","3gssB-4qxwA:undetectable","3gssB-4qxwA:20.00"],["3JAY_A_SAMA1101_0","STRUCTURAL PROTEIN VP3","4qxw","CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 1","Homo sapiens",5,"ASN A  61;SER A  62;ARG A  43;ASP A  82;ASN A  81","None;None;MLA A 201 (-2.8A);None;None","1.41A","3jayA-4qxwA:undetectable","3jayA-4qxwA:7.37"],["3JB3_A_SAMA1101_0","STRUCTURAL PROTEIN VP3","4qxw","CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 1","Homo sapiens",5,"ASN A  61;SER A  62;ARG A  43;ASP A  82;ASN A  81","None;None;MLA A 201 (-2.8A);None;None","1.42A","3jb3A-4qxwA:undetectable","3jb3A-4qxwA:7.37"]]