SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qxz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FKF_A_FK5A108_1 (FK506 BINDING PROTEIN)	4qxz	UNCHARACTERIZED PROTEIN (Staphylococcus aureus)	5 / 11	ILE A 11 TYR A 21 HIS A 48 ILE A 44 PHE A 96	None	1.39A	1fkfA-4qxzA: undetectable	1fkfA-4qxzA: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FKJ_A_FK5A108_1 (FK506 BINDING PROTEIN)	4qxz	UNCHARACTERIZED PROTEIN (Staphylococcus aureus)	5 / 11	ILE A 11 TYR A 21 HIS A 48 ILE A 44 PHE A 96	None	1.37A	1fkjA-4qxzA: undetectable	1fkjA-4qxzA: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FKE_A_FK5A108_1 (FK506 BINDING PROTEIN)	4qxz	UNCHARACTERIZED PROTEIN (Staphylococcus aureus)	5 / 11	ILE A 11 TYR A 21 HIS A 48 ILE A 44 PHE A 96	None	1.38A	2fkeA-4qxzA: undetectable	2fkeA-4qxzA: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FXD_A_DR7A102_1 (POL PROTEIN)	4qxz	UNCHARACTERIZED PROTEIN (Staphylococcus aureus)	5 / 11	GLY A 26 ALA A 6 ILE A 29 PHE A 78 VAL A 66	None	0.87A	2fxdA-4qxzA: undetectable	2fxdA-4qxzA: 18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MZR_C_PFLC409_1 (PROTON-GATED ION CHANNEL)	4qxz	UNCHARACTERIZED PROTEIN (Staphylococcus aureus)	5 / 10	TYR A 55 ILE A 94 ILE A 85 MET A 92 THR A 51	None	1.41A	5mzrC-4qxzA: undetectable	5mzrC-4qxzA: 18.67

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FKF_A_FK5A108_1","FK506 BINDING PROTEIN","4qxz","UNCHARACTERIZED PROTEIN","Staphylococcus aureus",5,"ILE A  11;TYR A  21;HIS A  48;ILE A  44;PHE A  96","None","1.39A","1fkfA-4qxzA:undetectable","1fkfA-4qxzA:21.95"],["1FKJ_A_FK5A108_1","FK506 BINDING PROTEIN","4qxz","UNCHARACTERIZED PROTEIN","Staphylococcus aureus",5,"ILE A  11;TYR A  21;HIS A  48;ILE A  44;PHE A  96","None","1.37A","1fkjA-4qxzA:undetectable","1fkjA-4qxzA:21.95"],["2FKE_A_FK5A108_1","FK506 BINDING PROTEIN","4qxz","UNCHARACTERIZED PROTEIN","Staphylococcus aureus",5,"ILE A  11;TYR A  21;HIS A  48;ILE A  44;PHE A  96","None","1.38A","2fkeA-4qxzA:undetectable","2fkeA-4qxzA:21.95"],["2FXD_A_DR7A102_1","POL PROTEIN","4qxz","UNCHARACTERIZED PROTEIN","Staphylococcus aureus",5,"GLY A  26;ALA A   6;ILE A  29;PHE A  78;VAL A  66","None","0.87A","2fxdA-4qxzA:undetectable","2fxdA-4qxzA:18.42"],["5MZR_C_PFLC409_1","PROTON-GATED ION CHANNEL","4qxz","UNCHARACTERIZED PROTEIN","Staphylococcus aureus",5,"TYR A  55;ILE A  94;ILE A  85;MET A  92;THR A  51","None","1.41A","5mzrC-4qxzA:undetectable","5mzrC-4qxzA:18.67"]]