SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qyb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 4qyb UNCHARACTERIZED
PROTEIN
(Burkholderia
cenocepacia) 		4 / 6 LEU A  98
ALA A 102
SER A  94
THR A 105
 None
 1.06A 1ictB-4qybA:
undetectable		 1ictB-4qybA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4qyb UNCHARACTERIZED
PROTEIN
(Burkholderia
cenocepacia) 		4 / 7 ILE A  56
LEU A  60
PHE A  62
ARG A 104
 None
 0.94A 3ag2N-4qybA:
undetectable
3ag2W-4qybA:
undetectable		 3ag2N-4qybA:
14.50
3ag2W-4qybA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4qyb UNCHARACTERIZED
PROTEIN
(Burkholderia
cenocepacia) 		4 / 7 ILE A  56
LEU A  60
PHE A  62
ARG A 104
 None
 1.01A 3ag4N-4qybA:
undetectable
3ag4W-4qybA:
undetectable		 3ag4N-4qybA:
14.50
3ag4W-4qybA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_A_TCWA1126_1
(TRANSTHYRETIN)		 4qyb UNCHARACTERIZED
PROTEIN
(Burkholderia
cenocepacia) 		4 / 6 LEU A  98
ALA A 102
SER A  94
THR A 105
 None
 0.88A 4d7bB-4qybA:
undetectable		 4d7bB-4qybA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 4qyb UNCHARACTERIZED
PROTEIN
(Burkholderia
cenocepacia) 		4 / 6 LEU A  98
ALA A 102
SER A  94
THR A 105
 None
 0.94A 4i89A-4qybA:
undetectable		 4i89A-4qybA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_J_SASJ804_1
(SEPIAPTERIN
REDUCTASE)		 4qyb UNCHARACTERIZED
PROTEIN
(Burkholderia
cenocepacia) 		5 / 12 LEU A 118
PHE A 111
TRP A  14
TYR A  13
ASP A 113
 None
 1.28A 4j7xJ-4qybA:
undetectable		 4j7xJ-4qybA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 4qyb UNCHARACTERIZED
PROTEIN
(Burkholderia
cenocepacia) 		4 / 7 LEU A  98
ALA A 102
SER A  94
THR A 105
 None
 0.81A 4pwjB-4qybA:
undetectable		 4pwjB-4qybA:
27.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4qyb UNCHARACTERIZED
PROTEIN
(Burkholderia
cenocepacia) 		4 / 6 ILE A  56
LEU A  60
PHE A  62
ARG A 104
 None
 1.00A 5b1aN-4qybA:
undetectable
5b1aW-4qybA:
undetectable		 5b1aN-4qybA:
14.50
5b1aW-4qybA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_B_4TXB201_1
(TRANSTHYRETIN)		 4qyb UNCHARACTERIZED
PROTEIN
(Burkholderia
cenocepacia) 		4 / 7 LEU A  98
ALA A 102
SER A  94
THR A 105
 None
 0.86A 5bojB-4qybA:
undetectable		 5bojB-4qybA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 4qyb UNCHARACTERIZED
PROTEIN
(Burkholderia
cenocepacia) 		4 / 6 LEU A  98
ALA A 102
SER A  94
THR A 105
 None
 0.92A 5l4iA-4qybA:
undetectable		 5l4iA-4qybA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_B_6J3B201_0
(TRANSTHYRETIN)		 4qyb UNCHARACTERIZED
PROTEIN
(Burkholderia
cenocepacia) 		4 / 6 LEU A  98
ALA A 102
SER A  94
THR A 105
 None
 0.88A 5l4iB-4qybA:
undetectable		 5l4iB-4qybA:
23.57