SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4r03'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 4r03 UNCHARACTERIZED
PROTEIN
(Parabacteroides
distasonis) 		3 / 3 ALA A  76
VAL A  87
TRP A  86
 None
None
PO4  A 203 (-3.9A)
 0.93A 1grmA-4r03A:
undetectable		 1grmA-4r03A:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 4r03 UNCHARACTERIZED
PROTEIN
(Parabacteroides
distasonis) 		3 / 3 ALA A  76
VAL A  87
TRP A  86
 None
None
PO4  A 203 (-3.9A)
 0.94A 1grmB-4r03A:
undetectable		 1grmB-4r03A:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 4r03 UNCHARACTERIZED
PROTEIN
(Parabacteroides
distasonis) 		4 / 8 GLU A  73
TYR A  94
TYR A 107
ILE A  42
 None
 1.07A 3jz0B-4r03A:
undetectable		 3jz0B-4r03A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5V_A_ACTA511_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4r03 UNCHARACTERIZED
PROTEIN
(Parabacteroides
distasonis) 		4 / 4 ASN A 116
PHE A 117
SER A 118
GLN A  91
 None
 1.37A 3v5vA-4r03A:
undetectable		 3v5vA-4r03A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_1
(FK506-BINDING
PROTEIN 1)		 4r03 UNCHARACTERIZED
PROTEIN
(Parabacteroides
distasonis) 		3 / 3 ILE A 126
PRO A 127
ILE A 103
 None
 0.46A 5hw8F-4r03A:
undetectable		 5hw8F-4r03A:
20.17